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407 related items for PubMed ID: 16026644

  • 1. Interactive effects of HDAC inhibitors and TRAIL on apoptosis are associated with changes in mitochondrial functions and expressions of cell cycle regulatory genes in multiple myeloma.
    Fandy TE, Shankar S, Ross DD, Sausville E, Srivastava RK.
    Neoplasia; 2005 Jul; 7(7):646-57. PubMed ID: 16026644
    [Abstract] [Full Text] [Related]

  • 2. Interactive effects of histone deacetylase inhibitors and TRAIL on apoptosis in human leukemia cells: involvement of both death receptor and mitochondrial pathways.
    Shankar S, Singh TR, Fandy TE, Luetrakul T, Ross DD, Srivastava RK.
    Int J Mol Med; 2005 Dec; 16(6):1125-38. PubMed ID: 16273296
    [Abstract] [Full Text] [Related]

  • 3. Simultaneous activation of the intrinsic and extrinsic pathways by histone deacetylase (HDAC) inhibitors and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) synergistically induces mitochondrial damage and apoptosis in human leukemia cells.
    Rosato RR, Almenara JA, Dai Y, Grant S.
    Mol Cancer Ther; 2003 Dec; 2(12):1273-84. PubMed ID: 14707268
    [Abstract] [Full Text] [Related]

  • 4. Synergistic induction of oxidative injury and apoptosis in human multiple myeloma cells by the proteasome inhibitor bortezomib and histone deacetylase inhibitors.
    Pei XY, Dai Y, Grant S.
    Clin Cancer Res; 2004 Jun 01; 10(11):3839-52. PubMed ID: 15173093
    [Abstract] [Full Text] [Related]

  • 5. Cotreatment with histone deacetylase inhibitor LAQ824 enhances Apo-2L/tumor necrosis factor-related apoptosis inducing ligand-induced death inducing signaling complex activity and apoptosis of human acute leukemia cells.
    Guo F, Sigua C, Tao J, Bali P, George P, Li Y, Wittmann S, Moscinski L, Atadja P, Bhalla K.
    Cancer Res; 2004 Apr 01; 64(7):2580-9. PubMed ID: 15059915
    [Abstract] [Full Text] [Related]

  • 6. Potent antileukemic interactions between flavopiridol and TRAIL/Apo2L involve flavopiridol-mediated XIAP downregulation.
    Rosato RR, Dai Y, Almenara JA, Maggio SC, Grant S.
    Leukemia; 2004 Nov 01; 18(11):1780-8. PubMed ID: 15385934
    [Abstract] [Full Text] [Related]

  • 7. Histone deacetylase inhibitors strongly sensitise neuroblastoma cells to TRAIL-induced apoptosis by a caspases-dependent increase of the pro- to anti-apoptotic proteins ratio.
    Mühlethaler-Mottet A, Flahaut M, Bourloud KB, Auderset K, Meier R, Joseph JM, Gross N.
    BMC Cancer; 2006 Aug 24; 6():214. PubMed ID: 16930472
    [Abstract] [Full Text] [Related]

  • 8. Trichostatin A sensitizes TRAIL-resistant myeloma cells by downregulation of the antiapoptotic Bcl-2 proteins.
    Fandy TE, Srivastava RK.
    Cancer Chemother Pharmacol; 2006 Oct 24; 58(4):471-7. PubMed ID: 16435155
    [Abstract] [Full Text] [Related]

  • 9. Histone deacetylase inhibitors upregulate death receptor 5/TRAIL-R2 and sensitize apoptosis induced by TRAIL/APO2-L in human malignant tumor cells.
    Nakata S, Yoshida T, Horinaka M, Shiraishi T, Wakada M, Sakai T.
    Oncogene; 2004 Aug 19; 23(37):6261-71. PubMed ID: 15208660
    [Abstract] [Full Text] [Related]

  • 10. The histone deacetylase inhibitor, suberoylanilide hydroxamic acid, overcomes resistance of human breast cancer cells to Apo2L/TRAIL.
    Butler LM, Liapis V, Bouralexis S, Welldon K, Hay S, Thai le M, Labrinidis A, Tilley WD, Findlay DM, Evdokiou A.
    Int J Cancer; 2006 Aug 15; 119(4):944-54. PubMed ID: 16550602
    [Abstract] [Full Text] [Related]

  • 11. The histone deacetylase inhibitor suberic bishydroxamate: a potential sensitizer of melanoma to TNF-related apoptosis-inducing ligand (TRAIL) induced apoptosis.
    Zhang XD, Gillespie SK, Borrow JM, Hersey P.
    Biochem Pharmacol; 2003 Oct 15; 66(8):1537-45. PubMed ID: 14555232
    [Abstract] [Full Text] [Related]

  • 12. Cooperative cytotoxicity of proteasome inhibitors and tumor necrosis factor-related apoptosis-inducing ligand in chemoresistant Bcl-2-overexpressing cells.
    Nencioni A, Wille L, Dal Bello G, Boy D, Cirmena G, Wesselborg S, Belka C, Brossart P, Patrone F, Ballestrero A.
    Clin Cancer Res; 2005 Jun 01; 11(11):4259-65. PubMed ID: 15930365
    [Abstract] [Full Text] [Related]

  • 13. 4-Hydroxytamoxifen inhibits proliferation of multiple myeloma cells in vitro through down-regulation of c-Myc, up-regulation of p27Kip1, and modulation of Bcl-2 family members.
    Gauduchon J, Gouilleux F, Maillard S, Marsaud V, Renoir JM, Sola B.
    Clin Cancer Res; 2005 Mar 15; 11(6):2345-54. PubMed ID: 15788686
    [Abstract] [Full Text] [Related]

  • 14. Requirement of p53 targets in chemosensitization of colonic carcinoma to death ligand therapy.
    Wang S, El-Deiry WS.
    Proc Natl Acad Sci U S A; 2003 Dec 09; 100(25):15095-100. PubMed ID: 14645705
    [Abstract] [Full Text] [Related]

  • 15. Transforming growth factor-beta1 inhibits all-trans retinoic acid-induced apoptosis.
    Soucek K, Pacherník J, Kubala L, Vondrácek J, Hofmanová J, Kozubík A.
    Leuk Res; 2006 May 09; 30(5):607-23. PubMed ID: 16242776
    [Abstract] [Full Text] [Related]

  • 16. TNF-related apoptosis-inducing ligand-induced apoptosis of melanoma is associated with changes in mitochondrial membrane potential and perinuclear clustering of mitochondria.
    Thomas WD, Zhang XD, Franco AV, Nguyen T, Hersey P.
    J Immunol; 2000 Nov 15; 165(10):5612-20. PubMed ID: 11067917
    [Abstract] [Full Text] [Related]

  • 17. Proteasome inhibitor MG132 upregulates death receptor 5 and cooperates with Apo2L/TRAIL to induce apoptosis in Bax-proficient and -deficient cells.
    He Q, Huang Y, Sheikh MS.
    Oncogene; 2004 Apr 01; 23(14):2554-8. PubMed ID: 14691451
    [Abstract] [Full Text] [Related]

  • 18. Histone deacetylase inhibitors activate INK4d gene through Sp1 site in its promoter.
    Yokota T, Matsuzaki Y, Miyazawa K, Zindy F, Roussel MF, Sakai T.
    Oncogene; 2004 Jul 08; 23(31):5340-9. PubMed ID: 15107822
    [Abstract] [Full Text] [Related]

  • 19. Pediatric rhabdomyosarcoma cell lines are resistant to Fas-induced apoptosis and highly sensitive to TRAIL-induced apoptosis.
    Petak I, Douglas L, Tillman DM, Vernes R, Houghton JA.
    Clin Cancer Res; 2000 Oct 08; 6(10):4119-27. PubMed ID: 11051265
    [Abstract] [Full Text] [Related]

  • 20. Differential roles of RelA (p65) and c-Rel subunits of nuclear factor kappa B in tumor necrosis factor-related apoptosis-inducing ligand signaling.
    Chen X, Kandasamy K, Srivastava RK.
    Cancer Res; 2003 Mar 01; 63(5):1059-66. PubMed ID: 12615723
    [Abstract] [Full Text] [Related]

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