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224 related items for PubMed ID: 16034090

  • 1. Specific role of phosphodiesterase 4B in lipopolysaccharide-induced signaling in mouse macrophages.
    Jin SL, Lan L, Zoudilova M, Conti M.
    J Immunol; 2005 Aug 01; 175(3):1523-31. PubMed ID: 16034090
    [Abstract] [Full Text] [Related]

  • 2. Nonredundant function of phosphodiesterases 4D and 4B in neutrophil recruitment to the site of inflammation.
    Ariga M, Neitzert B, Nakae S, Mottin G, Bertrand C, Pruniaux MP, Jin SL, Conti M.
    J Immunol; 2004 Dec 15; 173(12):7531-8. PubMed ID: 15585880
    [Abstract] [Full Text] [Related]

  • 3. Induction of the cyclic nucleotide phosphodiesterase PDE4B is essential for LPS-activated TNF-alpha responses.
    Jin SL, Conti M.
    Proc Natl Acad Sci U S A; 2002 May 28; 99(11):7628-33. PubMed ID: 12032334
    [Abstract] [Full Text] [Related]

  • 4. Phosphodiesterase 4B negatively regulates endotoxin-activated interleukin-1 receptor antagonist responses in macrophages.
    Yang JX, Hsieh KC, Chen YL, Lee CK, Conti M, Chuang TH, Wu CP, Jin SC.
    Sci Rep; 2017 Apr 06; 7():46165. PubMed ID: 28383060
    [Abstract] [Full Text] [Related]

  • 5. Suppression of human inflammatory cell function by subtype-selective PDE4 inhibitors correlates with inhibition of PDE4A and PDE4B.
    Manning CD, Burman M, Christensen SB, Cieslinski LB, Essayan DM, Grous M, Torphy TJ, Barnette MS.
    Br J Pharmacol; 1999 Dec 06; 128(7):1393-8. PubMed ID: 10602317
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of PDE3B augments PDE4 inhibitor-induced apoptosis in a subset of patients with chronic lymphocytic leukemia.
    Moon E, Lee R, Near R, Weintraub L, Wolda S, Lerner A.
    Clin Cancer Res; 2002 Feb 06; 8(2):589-95. PubMed ID: 11839681
    [Abstract] [Full Text] [Related]

  • 7. Regulation of phosphodiesterase-4 (PDE4) expression in mouse brain by repeated antidepressant treatment: comparison with rolipram.
    Dlaboga D, Hajjhussein H, O'Donnell JM.
    Brain Res; 2006 Jun 22; 1096(1):104-12. PubMed ID: 16730340
    [Abstract] [Full Text] [Related]

  • 8. Anti-inflammatory and utero-relaxant effects in human myometrium of new generation phosphodiesterase 4 inhibitors.
    Oger S, Méhats C, Barnette MS, Ferré F, Cabrol D, Leroy MJ.
    Biol Reprod; 2004 Feb 22; 70(2):458-64. PubMed ID: 14561639
    [Abstract] [Full Text] [Related]

  • 9. Antidepressant-like profile and reduced sensitivity to rolipram in mice deficient in the PDE4D phosphodiesterase enzyme.
    Zhang HT, Huang Y, Jin SL, Frith SA, Suvarna N, Conti M, O'Donnell JM.
    Neuropsychopharmacology; 2002 Oct 22; 27(4):587-95. PubMed ID: 12377395
    [Abstract] [Full Text] [Related]

  • 10. Interleukin-10 does not mediate the inhibitory effect of PDE-4 inhibitors and other cAMP-elevating drugs on lipopolysaccharide-induced tumors necrosis factor-alpha generation from human peripheral blood monocytes.
    Seldon PM, Barnes PJ, Giembycz MA.
    Cell Biochem Biophys; 1998 Oct 22; 29(1-2):179-201. PubMed ID: 9631245
    [Abstract] [Full Text] [Related]

  • 11. Evidence for a role of phosphodiesterase 4 in lipopolysaccharide-stimulated prostaglandin E2 production and matrix metalloproteinase-9 activity in human amniochorionic membranes.
    Oger S, Méhats C, Dallot E, Cabrol D, Leroy MJ.
    J Immunol; 2005 Jun 15; 174(12):8082-9. PubMed ID: 15944316
    [Abstract] [Full Text] [Related]

  • 12. Challenge of human Jurkat T-cells with the adenylate cyclase activator forskolin elicits major changes in cAMP phosphodiesterase (PDE) expression by up-regulating PDE3 and inducing PDE4D1 and PDE4D2 splice variants as well as down-regulating a novel PDE4A splice variant.
    Erdogan S, Houslay MD.
    Biochem J; 1997 Jan 01; 321 ( Pt 1)(Pt 1):165-75. PubMed ID: 9003416
    [Abstract] [Full Text] [Related]

  • 13. Characterization of the rolipram-sensitive, cyclic AMP-specific phosphodiesterases: identification and differential expression of immunologically distinct forms in the rat brain.
    Iona S, Cuomo M, Bushnik T, Naro F, Sette C, Hess M, Shelton ER, Conti M.
    Mol Pharmacol; 1998 Jan 01; 53(1):23-32. PubMed ID: 9443929
    [Abstract] [Full Text] [Related]

  • 14. Deletion of phosphodiesterase 4D in mice shortens alpha(2)-adrenoceptor-mediated anesthesia, a behavioral correlate of emesis.
    Robichaud A, Stamatiou PB, Jin SL, Lachance N, MacDonald D, Laliberté F, Liu S, Huang Z, Conti M, Chan CC.
    J Clin Invest; 2002 Oct 01; 110(7):1045-52. PubMed ID: 12370283
    [Abstract] [Full Text] [Related]

  • 15. Ferulic acid prevents LPS-induced up-regulation of PDE4B and stimulates the cAMP/CREB signaling pathway in PC12 cells.
    Huang H, Hong Q, Tan HL, Xiao CR, Gao Y.
    Acta Pharmacol Sin; 2016 Dec 01; 37(12):1543-1554. PubMed ID: 27665850
    [Abstract] [Full Text] [Related]

  • 16. Action of rolipram on specific PDE4 cAMP phosphodiesterase isoforms and on the phosphorylation of cAMP-response-element-binding protein (CREB) and p38 mitogen-activated protein (MAP) kinase in U937 monocytic cells.
    MacKenzie SJ, Houslay MD.
    Biochem J; 2000 Apr 15; 347(Pt 2):571-8. PubMed ID: 10749688
    [Abstract] [Full Text] [Related]

  • 17. Prolonged beta adrenoceptor stimulation up-regulates cAMP phosphodiesterase activity in human monocytes by increasing mRNA and protein for phosphodiesterases 4A and 4B.
    Manning CD, McLaughlin MM, Livi GP, Cieslinski LB, Torphy TJ, Barnette MS.
    J Pharmacol Exp Ther; 1996 Feb 15; 276(2):810-8. PubMed ID: 8632354
    [Abstract] [Full Text] [Related]

  • 18. Differential expression and function of phosphodiesterase 4 (PDE4) subtypes in human primary CD4+ T cells: predominant role of PDE4D.
    Peter D, Jin SL, Conti M, Hatzelmann A, Zitt C.
    J Immunol; 2007 Apr 15; 178(8):4820-31. PubMed ID: 17404263
    [Abstract] [Full Text] [Related]

  • 19. Effects of ciclamilast, a new PDE 4 PDE4 inhibitor, on airway hyperresponsiveness, PDE4D expression and airway inflammation in a murine model of asthma.
    Deng YM, Xie QM, Tang HF, Sun JG, Deng JF, Chen JQ, Yang SY.
    Eur J Pharmacol; 2006 Oct 10; 547(1-3):125-35. PubMed ID: 16956605
    [Abstract] [Full Text] [Related]

  • 20. Suppression of lipopolysaccharide-induced tumor necrosis factor-alpha generation from human peripheral blood monocytes by inhibitors of phosphodiesterase 4: interaction with stimulants of adenylyl cyclase.
    Seldon PM, Barnes PJ, Meja K, Giembycz MA.
    Mol Pharmacol; 1995 Oct 10; 48(4):747-57. PubMed ID: 7476903
    [Abstract] [Full Text] [Related]

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