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251 related items for PubMed ID: 16041196

  • 1. A mechanism for the potential proarrhythmic effect of acidosis, bradycardia, and hypokalemia on the blockade of human ether-a-go-go-related gene (HERG) channels.
    Lin C, Cvetanovic I, Ke X, Ranade V, Somberg J.
    Am J Ther; 2005; 12(4):328-36. PubMed ID: 16041196
    [Abstract] [Full Text] [Related]

  • 2. Acidification alters antiarrhythmic drug blockade of the ether-a-go-go-related Gene (HERG) Channels.
    Dong DL, Li Z, Wang HZ, Du ZM, Song WH, Yang BF.
    Basic Clin Pharmacol Toxicol; 2004 May; 94(5):209-12. PubMed ID: 15125690
    [Abstract] [Full Text] [Related]

  • 3. Extracellular acidification and hyperkalemia induce changes in HERG inhibition by ibutilide.
    Lin C, Ke X, Ranade V, Somberg J.
    Cardiology; 2008 May; 110(3):209-16. PubMed ID: 18057887
    [Abstract] [Full Text] [Related]

  • 4. Modulation of HERG potassium channels by extracellular magnesium and quinidine.
    Po SS, Wang DW, Yang IC, Johnson JP, Nie L, Bennett PB.
    J Cardiovasc Pharmacol; 1999 Feb; 33(2):181-5. PubMed ID: 10028924
    [Abstract] [Full Text] [Related]

  • 5. The influence of extracellular acidosis on the effect of IKr blockers.
    Lin C, Ke X, Cvetanovic I, Ranade V, Somberg J.
    J Cardiovasc Pharmacol Ther; 2005 Mar; 10(1):67-76. PubMed ID: 15821840
    [Abstract] [Full Text] [Related]

  • 6. Pharmacological inhibition of the hERG potassium channel is modulated by extracellular but not intracellular acidosis.
    DU CY, El Harchi A, Zhang YH, Orchard CH, Hancox JC.
    J Cardiovasc Electrophysiol; 2011 Oct; 22(10):1163-70. PubMed ID: 21489024
    [Abstract] [Full Text] [Related]

  • 7. The effect of high extracellular potassium on IKr inhibition by anti-arrhythmic agents.
    Lin C, Ke X, Cvetanovic I, Ranade V, Somberg J.
    Cardiology; 2007 Oct; 108(1):18-27. PubMed ID: 16960444
    [Abstract] [Full Text] [Related]

  • 8. Enhanced inhibitory effect of acidosis on hERG potassium channels that incorporate the hERG1b isoform.
    Du CY, El Harchi A, McPate MJ, Orchard CH, Hancox JC.
    Biochem Biophys Res Commun; 2011 Feb 11; 405(2):222-7. PubMed ID: 21219869
    [Abstract] [Full Text] [Related]

  • 9. Effect of azelastine on cardiac repolarization of guinea-pig cardiomyocytes, hERG K⁺ channel, and human L-type and T-type Ca²⁺ channel.
    Park MH, Lee SH, Chu DH, Won KH, Choi BH, Choe H, Jo SH.
    J Pharmacol Sci; 2013 Sep 20; 123(1):67-77. PubMed ID: 24005046
    [Abstract] [Full Text] [Related]

  • 10. The cardiac hERG/IKr potassium channel as pharmacological target: structure, function, regulation, and clinical applications.
    Thomas D, Karle CA, Kiehn J.
    Curr Pharm Des; 2006 Sep 20; 12(18):2271-83. PubMed ID: 16787254
    [Abstract] [Full Text] [Related]

  • 11. Block of HERG human K(+) channel and IKr of guinea pig cardiomyocytes by chlorpromazine.
    Lee SY, Choi SY, Youm JB, Ho WK, Earm YE, Lee CO, Jo SH.
    J Cardiovasc Pharmacol; 2004 May 20; 43(5):706-14. PubMed ID: 15071359
    [Abstract] [Full Text] [Related]

  • 12. Extracellular potassium dependency of block of HERG by quinidine and cisapride is primarily determined by the permeant ion and not by inactivation.
    Barrows B, Cheung K, Bialobrzeski T, Foster J, Schulze J, Miller A.
    Channels (Austin); 2009 May 20; 3(4):239-48. PubMed ID: 19617705
    [Abstract] [Full Text] [Related]

  • 13. The additive effects of the active component of grapefruit juice (naringenin) and antiarrhythmic drugs on HERG inhibition.
    Lin C, Ke X, Ranade V, Somberg J.
    Cardiology; 2008 May 20; 110(3):145-52. PubMed ID: 18057881
    [Abstract] [Full Text] [Related]

  • 14. The Susceptibilities of Human Ether-à-Go-Go-Related Gene Channel with the G487R Mutation to Arrhythmogenic Factors.
    Hisajima N, Hata Y, Kinoshita K, Fukushima T, Nishida N, Kano M, Tabata T.
    Biol Pharm Bull; 2015 May 20; 38(5):781-4. PubMed ID: 25947924
    [Abstract] [Full Text] [Related]

  • 15. Blockade of HERG human K+ channels and IKr of guinea-pig cardiomyocytes by the antipsychotic drug clozapine.
    Lee SY, Kim YJ, Kim KT, Choe H, Jo SH.
    Br J Pharmacol; 2006 Jun 20; 148(4):499-509. PubMed ID: 16633353
    [Abstract] [Full Text] [Related]

  • 16. Blockade of HERG human K+ channel and IKr of guinea pig cardiomyocytes by prochlorperazine.
    Kim MD, Eun SY, Jo SH.
    Eur J Pharmacol; 2006 Aug 21; 544(1-3):82-90. PubMed ID: 16860311
    [Abstract] [Full Text] [Related]

  • 17. A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel.
    Sanguinetti MC, Jiang C, Curran ME, Keating MT.
    Cell; 1995 Apr 21; 81(2):299-307. PubMed ID: 7736582
    [Abstract] [Full Text] [Related]

  • 18. In vitro modulation of HERG channels by organochlorine solvent trichlormethane as potential explanation for proarrhythmic effects of chloroform.
    Scholz EP, Alter M, Zitron E, Kiesecker C, Kathöfer S, Thomas D, Kreye VA, Kreuzer J, Becker R, Katus HA, Greten J, Karle CA.
    Toxicol Lett; 2006 Aug 20; 165(2):156-66. PubMed ID: 16647228
    [Abstract] [Full Text] [Related]

  • 19. Blockade of the human ether-a-go-go-related gene potassium channel by ketamine.
    Zhang P, Xing J, Luo A, Feng J, Liu Z, Gao C, Ma J.
    J Pharm Pharmacol; 2013 Sep 20; 65(9):1321-8. PubMed ID: 23927470
    [Abstract] [Full Text] [Related]

  • 20. Protriptyline block of the human ether-à-go-go-related gene (HERG) K+ channel.
    Jo SH, Hong HK, Chong SH, Choe H.
    Life Sci; 2008 Jan 30; 82(5-6):331-40. PubMed ID: 18191158
    [Abstract] [Full Text] [Related]

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