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Journal Abstract Search

573 related items for PubMed ID: 16055722

  • 1. A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons.
    Tasaki T, Mulder LC, Iwamatsu A, Lee MJ, Davydov IV, Varshavsky A, Muesing M, Kwon YT.
    Mol Cell Biol; 2005 Aug; 25(16):7120-36. PubMed ID: 16055722
    [Abstract] [Full Text] [Related]

  • 2. The substrate recognition domains of the N-end rule pathway.
    Tasaki T, Zakrzewska A, Dudgeon DD, Jiang Y, Lazo JS, Kwon YT.
    J Biol Chem; 2009 Jan 16; 284(3):1884-95. PubMed ID: 19008229
    [Abstract] [Full Text] [Related]

  • 3. Biochemical and genetic studies of UBR3, a ubiquitin ligase with a function in olfactory and other sensory systems.
    Tasaki T, Sohr R, Xia Z, Hellweg R, Hörtnagl H, Varshavsky A, Kwon YT.
    J Biol Chem; 2007 Jun 22; 282(25):18510-18520. PubMed ID: 17462990
    [Abstract] [Full Text] [Related]

  • 4. Impaired neurogenesis and cardiovascular development in mice lacking the E3 ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway.
    An JY, Seo JW, Tasaki T, Lee MJ, Varshavsky A, Kwon YT.
    Proc Natl Acad Sci U S A; 2006 Apr 18; 103(16):6212-7. PubMed ID: 16606826
    [Abstract] [Full Text] [Related]

  • 5. UBR box N-recognin-4 (UBR4), an N-recognin of the N-end rule pathway, and its role in yolk sac vascular development and autophagy.
    Tasaki T, Kim ST, Zakrzewska A, Lee BE, Kang MJ, Yoo YD, Cha-Molstad HJ, Hwang J, Soung NK, Sung KS, Kim SH, Nguyen MD, Sun M, Yi EC, Kim BY, Kwon YT.
    Proc Natl Acad Sci U S A; 2013 Mar 05; 110(10):3800-5. PubMed ID: 23431188
    [Abstract] [Full Text] [Related]

  • 6. The N-recognin UBR4 of the N-end rule pathway is required for neurogenesis and homeostasis of cell surface proteins.
    Kim ST, Lee YJ, Tasaki T, Hwang J, Kang MJ, Yi EC, Kim BY, Kwon YT.
    PLoS One; 2018 Mar 05; 13(8):e0202260. PubMed ID: 30157281
    [Abstract] [Full Text] [Related]

  • 7. The ATF3 Transcription Factor Is a Short-Lived Substrate of the Arg/N-Degron Pathway.
    Vu TTM, Varshavsky A.
    Biochemistry; 2020 Aug 04; 59(30):2796-2812. PubMed ID: 32692156
    [Abstract] [Full Text] [Related]

  • 8. The N-end rule and retroviral infection: no effect on integrase.
    Boso G, Tasaki T, Kwon YT, Somia NV.
    Virol J; 2013 Jul 13; 10():233. PubMed ID: 23849394
    [Abstract] [Full Text] [Related]

  • 9. UBR2 of the N-end rule pathway is required for chromosome stability via histone ubiquitylation in spermatocytes and somatic cells.
    An JY, Kim E, Zakrzewska A, Yoo YD, Jang JM, Han DH, Lee MJ, Seo JW, Lee YJ, Kim TY, de Rooij DG, Kim BY, Kwon YT.
    PLoS One; 2012 Jul 13; 7(5):e37414. PubMed ID: 22616001
    [Abstract] [Full Text] [Related]

  • 10. Signaling Pathways Regulated by UBR Box-Containing E3 Ligases.
    Kim JG, Shin HC, Seo T, Nawale L, Han G, Kim BY, Kim SJ, Cha-Molstad H.
    Int J Mol Sci; 2021 Aug 03; 22(15):. PubMed ID: 34361089
    [Abstract] [Full Text] [Related]

  • 11. Structural basis of substrate recognition and specificity in the N-end rule pathway.
    Matta-Camacho E, Kozlov G, Li FF, Gehring K.
    Nat Struct Mol Biol; 2010 Oct 03; 17(10):1182-7. PubMed ID: 20835242
    [Abstract] [Full Text] [Related]

  • 12. The N-recognin UBR4 of the N-end rule pathway is targeted to and required for the biogenesis of the early endosome.
    Kim ST, Lee YJ, Tasaki T, Mun SR, Hwang J, Kang MJ, Ganipisetti S, Yi EC, Kim BY, Kwon YT.
    J Cell Sci; 2018 Sep 10; 131(17):. PubMed ID: 30111582
    [Abstract] [Full Text] [Related]

  • 13. Synthetic heterovalent inhibitors targeting recognition E3 components of the N-end rule pathway.
    Lee MJ, Pal K, Tasaki T, Roy S, Jiang Y, An JY, Banerjee R, Kwon YT.
    Proc Natl Acad Sci U S A; 2008 Jan 08; 105(1):100-5. PubMed ID: 18162545
    [Abstract] [Full Text] [Related]

  • 14. The UBR-box and its relationship to binuclear RING-like treble clef zinc fingers.
    Kaur G, Subramanian S.
    Biol Direct; 2015 Jul 17; 10():36. PubMed ID: 26185100
    [Abstract] [Full Text] [Related]

  • 15. Pairs of dipeptides synergistically activate the binding of substrate by ubiquitin ligase through dissociation of its autoinhibitory domain.
    Du F, Navarro-Garcia F, Xia Z, Tasaki T, Varshavsky A.
    Proc Natl Acad Sci U S A; 2002 Oct 29; 99(22):14110-5. PubMed ID: 12391316
    [Abstract] [Full Text] [Related]

  • 16. Role of N-end rule ubiquitin ligases UBR1 and UBR2 in regulating the leucine-mTOR signaling pathway.
    Kume K, Iizumi Y, Shimada M, Ito Y, Kishi T, Yamaguchi Y, Handa H.
    Genes Cells; 2010 Apr 01; 15(4):339-49. PubMed ID: 20298436
    [Abstract] [Full Text] [Related]

  • 17. Female lethality and apoptosis of spermatocytes in mice lacking the UBR2 ubiquitin ligase of the N-end rule pathway.
    Kwon YT, Xia Z, An JY, Tasaki T, Davydov IV, Seo JW, Sheng J, Xie Y, Varshavsky A.
    Mol Cell Biol; 2003 Nov 01; 23(22):8255-71. PubMed ID: 14585983
    [Abstract] [Full Text] [Related]

  • 18. UBR7 functions with UBR5 in the Notch signaling pathway and is involved in a neurodevelopmental syndrome with epilepsy, ptosis, and hypothyroidism.
    Li C, Beauregard-Lacroix E, Kondratev C, Rousseau J, Heo AJ, Neas K, Graham BH, Rosenfeld JA, Bacino CA, Wagner M, Wenzel M, Al Mutairi F, Al Deiab H, Gleeson JG, Stanley V, Zaki MS, Kwon YT, Leroux MR, Campeau PM.
    Am J Hum Genet; 2021 Jan 07; 108(1):134-147. PubMed ID: 33340455
    [Abstract] [Full Text] [Related]

  • 19. Insights into the recognition mechanism in the UBR box of UBR4 for its specific substrates.
    Jeong DE, Lee HS, Ku B, Kim CH, Kim SJ, Shin HC.
    Commun Biol; 2023 Nov 29; 6(1):1214. PubMed ID: 38030679
    [Abstract] [Full Text] [Related]

  • 20. Substrate-binding sites of UBR1, the ubiquitin ligase of the N-end rule pathway.
    Xia Z, Webster A, Du F, Piatkov K, Ghislain M, Varshavsky A.
    J Biol Chem; 2008 Aug 29; 283(35):24011-28. PubMed ID: 18566452
    [Abstract] [Full Text] [Related]

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