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Journal Abstract Search

216 related items for PubMed ID: 16061414

  • 1. Catalytic mechanism of S-adenosylhomocysteine hydrolase: roles of His 54, Asp130, Glu155, Lys185, and Aspl89.
    Yamada T, Takata Y, Komoto J, Gomi T, Ogawa H, Fujioka M, Takusagawa F.
    Int J Biochem Cell Biol; 2005 Nov; 37(11):2417-35. PubMed ID: 16061414
    [Abstract] [Full Text] [Related]

  • 2. Crystal structure of S-adenosylhomocysteine hydrolase from rat liver.
    Hu Y, Komoto J, Huang Y, Gomi T, Ogawa H, Takata Y, Fujioka M, Takusagawa F.
    Biochemistry; 1999 Jun 29; 38(26):8323-33. PubMed ID: 10387078
    [Abstract] [Full Text] [Related]

  • 3. Catalytic mechanism of S-adenosylhomocysteine hydrolase. Site-directed mutagenesis of Asp-130, Lys-185, Asp-189, and Asn-190.
    Takata Y, Yamada T, Huang Y, Komoto J, Gomi T, Ogawa H, Fujioka M, Takusagawa F.
    J Biol Chem; 2002 Jun 21; 277(25):22670-6. PubMed ID: 11927587
    [Abstract] [Full Text] [Related]

  • 4. Catalytic strategy of S-adenosyl-L-homocysteine hydrolase: transition-state stabilization and the avoidance of abortive reactions.
    Yang X, Hu Y, Yin DH, Turner MA, Wang M, Borchardt RT, Howell PL, Kuczera K, Schowen RL.
    Biochemistry; 2003 Feb 25; 42(7):1900-9. PubMed ID: 12590576
    [Abstract] [Full Text] [Related]

  • 5. A single mutation at Tyr143 of human S-adenosylhomocysteine hydrolase renders the enzyme thermosensitive and affects the oxidation state of bound cofactor nicotinamide-adenine dinucleotide.
    Beluzić R, Cuk M, Pavkov T, Fumić K, Barić I, Mudd SH, Jurak I, Vugrek O.
    Biochem J; 2006 Dec 01; 400(2):245-53. PubMed ID: 16872278
    [Abstract] [Full Text] [Related]

  • 6. Crystal structure of the S-adenosylmethionine synthetase ternary complex: a novel catalytic mechanism of S-adenosylmethionine synthesis from ATP and Met.
    Komoto J, Yamada T, Takata Y, Markham GD, Takusagawa F.
    Biochemistry; 2004 Feb 24; 43(7):1821-31. PubMed ID: 14967023
    [Abstract] [Full Text] [Related]

  • 7. Copper ions inhibit S-adenosylhomocysteine hydrolase by causing dissociation of NAD+ cofactor.
    Li M, Li Y, Chen J, Wei W, Pan X, Liu J, Liu Q, Leu W, Zhang L, Yang X, Lu J, Wang K.
    Biochemistry; 2007 Oct 16; 46(41):11451-8. PubMed ID: 17892301
    [Abstract] [Full Text] [Related]

  • 8. S-Adenosylhomocysteine hydrolase (AdoHcyase) deficiency: enzymatic capabilities of human AdoHcyase are highly effected by changes to codon 89 and its surrounding residues.
    Beluzić R, Cuk M, Pavkov T, Barić I, Vugrek O.
    Biochem Biophys Res Commun; 2008 Mar 28; 368(1):30-6. PubMed ID: 18211827
    [Abstract] [Full Text] [Related]

  • 9. Mechanisms for auto-inhibition and forced product release in glycine N-methyltransferase: crystal structures of wild-type, mutant R175K and S-adenosylhomocysteine-bound R175K enzymes.
    Huang Y, Komoto J, Konishi K, Takata Y, Ogawa H, Gomi T, Fujioka M, Takusagawa F.
    J Mol Biol; 2000 Apr 21; 298(1):149-62. PubMed ID: 10756111
    [Abstract] [Full Text] [Related]

  • 10. Effects of ligand binding and oxidation on hinge-bending motions in S-adenosyl-L-homocysteine hydrolase.
    Wang M, Unruh JR, Johnson CK, Kuczera K, Schowen RL, Borchardt RT.
    Biochemistry; 2006 Jun 27; 45(25):7778-86. PubMed ID: 16784229
    [Abstract] [Full Text] [Related]

  • 11. Effects of site-directed mutagenesis on structure and function of recombinant rat liver S-adenosylhomocysteine hydrolase. Crystal structure of D244E mutant enzyme.
    Komoto J, Huang Y, Gomi T, Ogawa H, Takata Y, Fujioka M, Takusagawa F.
    J Biol Chem; 2000 Oct 13; 275(41):32147-56. PubMed ID: 10913437
    [Abstract] [Full Text] [Related]

  • 12. Substrate binding stabilizes S-adenosylhomocysteine hydrolase in a closed conformation.
    Yin D, Yang X, Hu Y, Kuczera K, Schowen RL, Borchardt RT, Squier TC.
    Biochemistry; 2000 Aug 15; 39(32):9811-8. PubMed ID: 10933798
    [Abstract] [Full Text] [Related]

  • 13. Domain motions and the open-to-closed conformational transition of an enzyme: a normal mode analysis of S-adenosyl-L-homocysteine hydrolase.
    Wang M, Borchardt RT, Schowen RL, Kuczera K.
    Biochemistry; 2005 May 17; 44(19):7228-39. PubMed ID: 15882061
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of S-adenosylhomocysteine hydrolase by acyclic sugar adenosine analogue D-eritadenine. Crystal structure of S-adenosylhomocysteine hydrolase complexed with D-eritadenine.
    Huang Y, Komoto J, Takata Y, Powell DR, Gomi T, Ogawa H, Fujioka M, Takusagawa F.
    J Biol Chem; 2002 Mar 01; 277(9):7477-82. PubMed ID: 11741948
    [Abstract] [Full Text] [Related]

  • 15. Adenosine binding sites at S-adenosylhomocysteine hydrolase are controlled by the NAD+/NADH ratio of the enzyme.
    Kloor D, Lüdtke A, Stoeva S, Osswald H.
    Biochem Pharmacol; 2003 Dec 01; 66(11):2117-23. PubMed ID: 14609736
    [Abstract] [Full Text] [Related]

  • 16. Catalytic mechanism of guanidinoacetate methyltransferase: crystal structures of guanidinoacetate methyltransferase ternary complexes.
    Komoto J, Yamada T, Takata Y, Konishi K, Ogawa H, Gomi T, Fujioka M, Takusagawa F.
    Biochemistry; 2004 Nov 16; 43(45):14385-94. PubMed ID: 15533043
    [Abstract] [Full Text] [Related]

  • 17. NMR docking of the competitive inhibitor thymidine 3',5'-diphosphate into the X-ray structure of staphylococcal nuclease.
    Weber DJ, Serpersu EH, Gittis AG, Lattman EE, Mildvan AS.
    Proteins; 1993 Sep 16; 17(1):20-35. PubMed ID: 8234242
    [Abstract] [Full Text] [Related]

  • 18. S-adenosylhomocysteine hydrolase from the archaeon Pyrococcus furiosus: biochemical characterization and analysis of protein structure by comparative molecular modeling.
    Porcelli M, Moretti MA, Concilio L, Forte S, Merlino A, Graziano G, Cacciapuoti G.
    Proteins; 2005 Mar 01; 58(4):815-25. PubMed ID: 15645450
    [Abstract] [Full Text] [Related]

  • 19. The mechanism of inactivation of human placental S-adenosylhomocysteine hydrolase by (E)-4',5'-didehydro-5'-methoxyadenosine and adenosine 5'-carboxaldehyde oxime.
    Huang H, Yuan CS, Wnuk SF, Robins MJ, Borchardt RT.
    Arch Biochem Biophys; 1997 Jul 01; 343(1):109-17. PubMed ID: 9210652
    [Abstract] [Full Text] [Related]

  • 20. Kinetic and structural studies on the catalytic role of the aspartic acid residue conserved in copper amine oxidase.
    Chiu YC, Okajima T, Murakawa T, Uchida M, Taki M, Hirota S, Kim M, Yamaguchi H, Kawano Y, Kamiya N, Kuroda S, Hayashi H, Yamamoto Y, Tanizawa K.
    Biochemistry; 2006 Apr 04; 45(13):4105-20. PubMed ID: 16566584
    [Abstract] [Full Text] [Related]

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