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Journal Abstract Search

90 related items for PubMed ID: 1606632

  • 1. Renin inhibitors. I. Synthesis and structure-activity relationships of transition-state inhibitors containing homostatine analogues at the scissile bond.
    Atsuumi S, Nakano M, Koike Y, Tanaka S, Matsuyama K, Nakano M, Morishima H.
    Chem Pharm Bull (Tokyo); 1992 Feb; 40(2):364-70. PubMed ID: 1606632
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  • 2. Renin inhibitors based on novel dipeptide analogues. Incorporation of the dehydrohydroxyethylene isostere at the scissile bond.
    Kempf DJ, de Lara E, Stein HH, Cohen J, Plattner JJ.
    J Med Chem; 1987 Nov; 30(11):1978-83. PubMed ID: 3312604
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  • 3. Renin inhibitors. Dipeptide analogues of angiotensinogen utilizing a dihydroxyethylene transition-state mimic at the scissile bond to impart greater inhibitory potency.
    Luly JR, BaMaung N, Soderquist J, Fung AK, Stein H, Kleinert HD, Marcotte PA, Egan DA, Bopp B, Merits I.
    J Med Chem; 1988 Dec; 31(12):2264-76. PubMed ID: 3143009
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  • 5. Orally potent human renin inhibitors derived from angiotensinogen transition state: design, synthesis, and mode of interaction.
    Iizuka K, Kamijo T, Harada H, Akahane K, Kubota T, Umeyama H, Ishida T, Kiso Y.
    J Med Chem; 1990 Oct; 33(10):2707-14. PubMed ID: 2120440
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  • 7. Synthesis of human renin inhibitory peptides, angiotensinogen transition-state analogs containing a retro-inverso amide bond.
    Harada H, Iizuka K, Kamijo T, Akahane K, Yamamoto R, Nakano Y, Tsubaki A, Kubota T, Shimaoka I, Umeyama H.
    Chem Pharm Bull (Tokyo); 1990 Nov; 38(11):3042-7. PubMed ID: 2085885
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  • 10. Design and synthesis of renin inhibitors: incorporation of transition-state isostere side chains that span from the S1 to the S3 binding pockets and examination of P3-modified renin inhibitors.
    Plummer MS, Shahripour A, Kaltenbronn JS, Lunney EA, Steinbaugh BA, Hamby JM, Hamilton HW, Sawyer TK, Humblet C, Doherty AM.
    J Med Chem; 1995 Jul 21; 38(15):2893-905. PubMed ID: 7636850
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  • 11. Renin inhibitors. Design of angiotensinogen transition-state analogues containing novel. (2R,3R,4R,5S)-5-amino-3,4-dihydroxy-2-isopropyl-7-methyloctanoic acid.
    Thaisrivongs S, Pals DT, Kroll LT, Turner SR, Han FS.
    J Med Chem; 1987 Jun 21; 30(6):976-82. PubMed ID: 3295239
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  • 16. Synthesis and renin inhibitory activity of angiotensinogen analogues having dehydrostatine, Leu psi [CH2S]Val, or Leu psi [CH2SO]Val at the P1-P1' cleavage site.
    Smith CW, Saneii HH, Sawyer TK, Pals DT, Scahill TA, Kamdar BV, Lawson JA.
    J Med Chem; 1988 Jul 21; 31(7):1377-82. PubMed ID: 3290486
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