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Journal Abstract Search

203 related items for PubMed ID: 16075413

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  • 2. O6-(4-bromothenyl)guanine reverses temozolomide resistance in human breast tumour MCF-7 cells and xenografts.
    Clemons M, Kelly J, Watson AJ, Howell A, McElhinney RS, McMurry TB, Margison GP.
    Br J Cancer; 2005 Nov 14; 93(10):1152-6. PubMed ID: 16278661
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  • 8. Characterization of the P140K, PVP(138-140)MLK, and G156A O6-methylguanine-DNA methyltransferase mutants: implications for drug resistance gene therapy.
    Davis BM, Roth JC, Liu L, Xu-Welliver M, Pegg AE, Gerson SL.
    Hum Gene Ther; 1999 Nov 20; 10(17):2769-78. PubMed ID: 10584923
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  • 9. Sensitization of pancreatic tumor xenografts to carmustine and temozolomide by inactivation of their O6-Methylguanine-DNA methyltransferase with O6-benzylguanine or O6-benzyl-2'-deoxyguanosine.
    Kokkinakis DM, Ahmed MM, Chendil D, Moschel RC, Pegg AE.
    Clin Cancer Res; 2003 Sep 01; 9(10 Pt 1):3801-7. PubMed ID: 14506174
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  • 11. Dual agent chemoprotection by retroviral co-expression of either MDR1 or MRP1 with the P140K mutant of O6-methylguanine-DNA-methyl transferase.
    Southgate TD, Garside E, Margison GP, Fairbairn LJ.
    J Gene Med; 2006 Aug 01; 8(8):972-9. PubMed ID: 16733832
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  • 14. Mitochondrial targeting of human O6-methylguanine DNA methyltransferase protects against cell killing by chemotherapeutic alkylating agents.
    Cai S, Xu Y, Cooper RJ, Ferkowicz MJ, Hartwell JR, Pollok KE, Kelley MR.
    Cancer Res; 2005 Apr 15; 65(8):3319-27. PubMed ID: 15833865
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  • 17. Protection and in vivo selection of hematopoietic stem cells using temozolomide, O6-benzylguanine, and an alkyltransferase-expressing retroviral vector.
    Sawai N, Zhou S, Vanin EF, Houghton P, Brent TP, Sorrentino BP.
    Mol Ther; 2001 Jan 15; 3(1):78-87. PubMed ID: 11162314
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  • 18. Nuclear-localizing O6-benzylguanine-resistant GFP-MGMT fusion protein as a novel in vivo selection marker.
    Choi U, DeRavin SS, Yamashita K, Whiting-Theobald N, Linton GF, Loktionova NA, Pegg AE, Malech HL.
    Exp Hematol; 2004 Aug 15; 32(8):709-19. PubMed ID: 15308322
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  • 19. O6-methylguanine-DNA methyltransferase, O6-benzylguanine, and resistance to clinical alkylators in pediatric primary brain tumor cell lines.
    Bobola MS, Silber JR, Ellenbogen RG, Geyer JR, Blank A, Goff RD.
    Clin Cancer Res; 2005 Apr 01; 11(7):2747-55. PubMed ID: 15814657
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  • 20. A single cycle of treatment with temozolomide, alone or combined with O(6)-benzylguanine, induces strong chemoresistance in melanoma cell clones in vitro: role of O(6)-methylguanine-DNA methyltransferase and the mismatch repair system.
    Alvino E, Castiglia D, Caporali S, Pepponi R, Caporaso P, Lacal PM, Marra G, Fischer F, Zambruno G, Bonmassar E, Jiricny J, D'Atri S.
    Int J Oncol; 2006 Oct 01; 29(4):785-97. PubMed ID: 16964376
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