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Journal Abstract Search


173 related items for PubMed ID: 16079140

  • 1. The origin of C1A-C2 interdomain interactions in protein kinase Calpha.
    Stahelin RV, Wang J, Blatner NR, Rafter JD, Murray D, Cho W.
    J Biol Chem; 2005 Oct 28; 280(43):36452-63. PubMed ID: 16079140
    [Abstract] [Full Text] [Related]

  • 2. Mechanism of diacylglycerol-induced membrane targeting and activation of protein kinase Cdelta.
    Stahelin RV, Digman MA, Medkova M, Ananthanarayanan B, Rafter JD, Melowic HR, Cho W.
    J Biol Chem; 2004 Jul 09; 279(28):29501-12. PubMed ID: 15105418
    [Abstract] [Full Text] [Related]

  • 3. Activation mechanisms of conventional protein kinase C isoforms are determined by the ligand affinity and conformational flexibility of their C1 domains.
    Ananthanarayanan B, Stahelin RV, Digman MA, Cho W.
    J Biol Chem; 2003 Nov 21; 278(47):46886-94. PubMed ID: 12954613
    [Abstract] [Full Text] [Related]

  • 4. Curcumin Inhibits Protein Kinase Cα Activity by Binding to Its C1 Domain.
    Pany S, You Y, Das J.
    Biochemistry; 2016 Nov 15; 55(45):6327-6336. PubMed ID: 27776404
    [Abstract] [Full Text] [Related]

  • 5. Single-molecule studies reveal a hidden key step in the activation mechanism of membrane-bound protein kinase C-α.
    Ziemba BP, Li J, Landgraf KE, Knight JD, Voth GA, Falke JJ.
    Biochemistry; 2014 Mar 18; 53(10):1697-713. PubMed ID: 24559055
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and phorbol ester binding of the cysteine-rich domains of diacylglycerol kinase (DGK) isozymes. DGKgamma and DGKbeta are new targets of tumor-promoting phorbol esters.
    Shindo M, Irie K, Masuda A, Ohigashi H, Shirai Y, Miyasaka K, Saito N.
    J Biol Chem; 2003 May 16; 278(20):18448-54. PubMed ID: 12621060
    [Abstract] [Full Text] [Related]

  • 7. Interplay of C1 and C2 domains of protein kinase C-alpha in its membrane binding and activation.
    Medkova M, Cho W.
    J Biol Chem; 1999 Jul 09; 274(28):19852-61. PubMed ID: 10391930
    [Abstract] [Full Text] [Related]

  • 8. Differential roles of phosphatidylserine, PtdIns(4,5)P2, and PtdIns(3,4,5)P3 in plasma membrane targeting of C2 domains. Molecular dynamics simulation, membrane binding, and cell translocation studies of the PKCalpha C2 domain.
    Manna D, Bhardwaj N, Vora MS, Stahelin RV, Lu H, Cho W.
    J Biol Chem; 2008 Sep 19; 283(38):26047-58. PubMed ID: 18621733
    [Abstract] [Full Text] [Related]

  • 9. Mechanism of specific membrane targeting by C2 domains: localized pools of target lipids enhance Ca2+ affinity.
    Corbin JA, Evans JH, Landgraf KE, Falke JJ.
    Biochemistry; 2007 Apr 10; 46(14):4322-36. PubMed ID: 17367165
    [Abstract] [Full Text] [Related]

  • 10. Individual C1 domains of PKD3 in phorbol ester-induced plasma membrane translocation of PKD3 in intact cells.
    Anderson G, Chen J, Wang QJ.
    Cell Signal; 2005 Nov 10; 17(11):1397-411. PubMed ID: 15927450
    [Abstract] [Full Text] [Related]

  • 11. Selective binding of phorbol esters and diacylglycerol by individual C1 domains of the PKD family.
    Chen J, Deng F, Li J, Wang QJ.
    Biochem J; 2008 Apr 15; 411(2):333-42. PubMed ID: 18076381
    [Abstract] [Full Text] [Related]

  • 12. Roles of ionic residues of the C1 domain in protein kinase C-alpha activation and the origin of phosphatidylserine specificity.
    Bittova L, Stahelin RV, Cho W.
    J Biol Chem; 2001 Feb 09; 276(6):4218-26. PubMed ID: 11029472
    [Abstract] [Full Text] [Related]

  • 13. PKCalpha: a versatile key for decoding the cellular calcium toolkit.
    Reither G, Schaefer M, Lipp P.
    J Cell Biol; 2006 Aug 14; 174(4):521-33. PubMed ID: 16893971
    [Abstract] [Full Text] [Related]

  • 14. Mechanism of diacylglycerol-induced membrane targeting and activation of protein kinase Ctheta.
    Melowic HR, Stahelin RV, Blatner NR, Tian W, Hayashi K, Altman A, Cho W.
    J Biol Chem; 2007 Jul 20; 282(29):21467-76. PubMed ID: 17548359
    [Abstract] [Full Text] [Related]

  • 15. Molecular mechanisms of PKCalpha localization and activation by arachidonic acid. The C2 domain also plays a role.
    López-Nicolás R, López-Andreo MJ, Marín-Vicente C, Gómez-Fernández JC, Corbalán-García S.
    J Mol Biol; 2006 Apr 07; 357(4):1105-20. PubMed ID: 16476439
    [Abstract] [Full Text] [Related]

  • 16. Specific translocation of protein kinase Calpha to the plasma membrane requires both Ca2+ and PIP2 recognition by its C2 domain.
    Evans JH, Murray D, Leslie CC, Falke JJ.
    Mol Biol Cell; 2006 Jan 07; 17(1):56-66. PubMed ID: 16236797
    [Abstract] [Full Text] [Related]

  • 17. Diacylglycerol-induced membrane targeting and activation of protein kinase Cepsilon: mechanistic differences between protein kinases Cdelta and Cepsilon.
    Stahelin RV, Digman MA, Medkova M, Ananthanarayanan B, Melowic HR, Rafter JD, Cho W.
    J Biol Chem; 2005 May 20; 280(20):19784-93. PubMed ID: 15769752
    [Abstract] [Full Text] [Related]

  • 18. Electrostatic and hydrophobic interactions differentially tune membrane binding kinetics of the C2 domain of protein kinase Cα.
    Scott AM, Antal CE, Newton AC.
    J Biol Chem; 2013 Jun 07; 288(23):16905-16915. PubMed ID: 23589289
    [Abstract] [Full Text] [Related]

  • 19. Structural determinants of phorbol ester binding activity of the C1a and C1b domains of protein kinase C theta.
    Czikora A, Pany S, You Y, Saini AS, Lewin NE, Mitchell GA, Abramovitz A, Kedei N, Blumberg PM, Das J.
    Biochim Biophys Acta Biomembr; 2018 May 07; 1860(5):1046-1056. PubMed ID: 29317197
    [Abstract] [Full Text] [Related]

  • 20. Characterization of the interaction of phorbol esters with the C1 domain of MRCK (myotonic dystrophy kinase-related Cdc42 binding kinase) alpha/beta.
    Choi SH, Czifra G, Kedei N, Lewin NE, Lazar J, Pu Y, Marquez VE, Blumberg PM.
    J Biol Chem; 2008 Apr 18; 283(16):10543-9. PubMed ID: 18263588
    [Abstract] [Full Text] [Related]


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