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Journal Abstract Search

1560 related items for PubMed ID: 16079851

  • 1. Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis.
    Chen Z, Trotman LC, Shaffer D, Lin HK, Dotan ZA, Niki M, Koutcher JA, Scher HI, Ludwig T, Gerald W, Cordon-Cardo C, Pandolfi PP.
    Nature; 2005 Aug 04; 436(7051):725-30. PubMed ID: 16079851
    [Abstract] [Full Text] [Related]

  • 2. Cancer: crime and punishment.
    Sharpless NE, DePinho RA.
    Nature; 2005 Aug 04; 436(7051):636-7. PubMed ID: 16079829
    [No Abstract] [Full Text] [Related]

  • 3. Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence.
    Lin HK, Chen Z, Wang G, Nardella C, Lee SW, Chan CH, Yang WL, Wang J, Egia A, Nakayama KI, Cordon-Cardo C, Teruya-Feldstein J, Pandolfi PP.
    Nature; 2010 Mar 18; 464(7287):374-9. PubMed ID: 20237562
    [Abstract] [Full Text] [Related]

  • 4. Genetic analysis of Pten and Ink4a/Arf interactions in the suppression of tumorigenesis in mice.
    You MJ, Castrillon DH, Bastian BC, O'Hagan RC, Bosenberg MW, Parsons R, Chin L, DePinho RA.
    Proc Natl Acad Sci U S A; 2002 Feb 05; 99(3):1455-60. PubMed ID: 11818530
    [Abstract] [Full Text] [Related]

  • 5. Methylseleninic Acid Superactivates p53-Senescence Cancer Progression Barrier in Prostate Lesions of Pten-Knockout Mouse.
    Wang L, Guo X, Wang J, Jiang C, Bosland MC, Lü J, Deng Y.
    Cancer Prev Res (Phila); 2016 Jan 05; 9(1):35-42. PubMed ID: 26511486
    [Abstract] [Full Text] [Related]

  • 6. Differential p53-independent outcomes of p19(Arf) loss in oncogenesis.
    Chen Z, Carracedo A, Lin HK, Koutcher JA, Behrendt N, Egia A, Alimonti A, Carver BS, Gerald W, Teruya-Feldstein J, Loda M, Pandolfi PP.
    Sci Signal; 2009 Aug 18; 2(84):ra44. PubMed ID: 19690330
    [Abstract] [Full Text] [Related]

  • 7. Genetic analysis of Pten and Tsc2 functional interactions in the mouse reveals asymmetrical haploinsufficiency in tumor suppression.
    Ma L, Teruya-Feldstein J, Behrendt N, Chen Z, Noda T, Hino O, Cordon-Cardo C, Pandolfi PP.
    Genes Dev; 2005 Aug 01; 19(15):1779-86. PubMed ID: 16027168
    [Abstract] [Full Text] [Related]

  • 8. Adenoviral-mediated expression of MMAC/PTEN inhibits proliferation and metastasis of human prostate cancer cells.
    Davies MA, Kim SJ, Parikh NU, Dong Z, Bucana CD, Gallick GE.
    Clin Cancer Res; 2002 Jun 01; 8(6):1904-14. PubMed ID: 12060635
    [Abstract] [Full Text] [Related]

  • 9. Pten and p27KIP1 cooperate in prostate cancer tumor suppression in the mouse.
    Di Cristofano A, De Acetis M, Koff A, Cordon-Cardo C, Pandolfi PP.
    Nat Genet; 2001 Feb 01; 27(2):222-4. PubMed ID: 11175795
    [Abstract] [Full Text] [Related]

  • 10. A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis.
    Alimonti A, Nardella C, Chen Z, Clohessy JG, Carracedo A, Trotman LC, Cheng K, Varmeh S, Kozma SC, Thomas G, Rosivatz E, Woscholski R, Cognetti F, Scher HI, Pandolfi PP.
    J Clin Invest; 2010 Mar 01; 120(3):681-93. PubMed ID: 20197621
    [Abstract] [Full Text] [Related]

  • 11. UBTD1 induces cellular senescence through an UBTD1-Mdm2/p53 positive feedback loop.
    Zhang XW, Wang XF, Ni SJ, Qin W, Zhao LQ, Hua RX, Lu YW, Li J, Dimri GP, Guo WJ.
    J Pathol; 2015 Mar 01; 235(4):656-67. PubMed ID: 25382750
    [Abstract] [Full Text] [Related]

  • 12. NFATc1 promotes prostate tumorigenesis and overcomes PTEN loss-induced senescence.
    Manda KR, Tripathi P, Hsi AC, Ning J, Ruzinova MB, Liapis H, Bailey M, Zhang H, Maher CA, Humphrey PA, Andriole GL, Ding L, You Z, Chen F.
    Oncogene; 2016 Jun 23; 35(25):3282-92. PubMed ID: 26477312
    [Abstract] [Full Text] [Related]

  • 13. Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression.
    Kwabi-Addo B, Giri D, Schmidt K, Podsypanina K, Parsons R, Greenberg N, Ittmann M.
    Proc Natl Acad Sci U S A; 2001 Sep 25; 98(20):11563-8. PubMed ID: 11553783
    [Abstract] [Full Text] [Related]

  • 14. TAp63 induces senescence and suppresses tumorigenesis in vivo.
    Guo X, Keyes WM, Papazoglu C, Zuber J, Li W, Lowe SW, Vogel H, Mills AA.
    Nat Cell Biol; 2009 Dec 25; 11(12):1451-7. PubMed ID: 19898465
    [Abstract] [Full Text] [Related]

  • 15. PTEN deletion in luminal cells of mature prostate induces replication stress and senescence in vivo.
    Parisotto M, Grelet E, El Bizri R, Dai Y, Terzic J, Eckert D, Gargowitsch L, Bornert JM, Metzger D.
    J Exp Med; 2018 Jun 04; 215(6):1749-1763. PubMed ID: 29743291
    [Abstract] [Full Text] [Related]

  • 16. CKIα ablation highlights a critical role for p53 in invasiveness control.
    Elyada E, Pribluda A, Goldstein RE, Morgenstern Y, Brachya G, Cojocaru G, Snir-Alkalay I, Burstain I, Haffner-Krausz R, Jung S, Wiener Z, Alitalo K, Oren M, Pikarsky E, Ben-Neriah Y.
    Nature; 2011 Feb 17; 470(7334):409-13. PubMed ID: 21331045
    [Abstract] [Full Text] [Related]

  • 17. Vulnerabilities of PTEN-TP53-deficient prostate cancers to compound PARP-PI3K inhibition.
    González-Billalabeitia E, Seitzer N, Song SJ, Song MS, Patnaik A, Liu XS, Epping MT, Papa A, Hobbs RM, Chen M, Lunardi A, Ng C, Webster KA, Signoretti S, Loda M, Asara JM, Nardella C, Clohessy JG, Cantley LC, Pandolfi PP.
    Cancer Discov; 2014 Aug 17; 4(8):896-904. PubMed ID: 24866151
    [Abstract] [Full Text] [Related]

  • 18. Oncogene-induced senescence as an initial barrier in lymphoma development.
    Braig M, Lee S, Loddenkemper C, Rudolph C, Peters AH, Schlegelberger B, Stein H, Dörken B, Jenuwein T, Schmitt CA.
    Nature; 2005 Aug 04; 436(7051):660-5. PubMed ID: 16079837
    [Abstract] [Full Text] [Related]

  • 19. Orphan nuclear receptor TLX functions as a potent suppressor of oncogene-induced senescence in prostate cancer via its transcriptional co-regulation of the CDKN1A (p21(WAF1) (/) (CIP1) ) and SIRT1 genes.
    Wu D, Yu S, Jia L, Zou C, Xu Z, Xiao L, Wong KB, Ng CF, Chan FL.
    J Pathol; 2015 May 04; 236(1):103-15. PubMed ID: 25557355
    [Abstract] [Full Text] [Related]

  • 20. p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas.
    Singh B, Reddy PG, Goberdhan A, Walsh C, Dao S, Ngai I, Chou TC, O-Charoenrat P, Levine AJ, Rao PH, Stoffel A.
    Genes Dev; 2002 Apr 15; 16(8):984-93. PubMed ID: 11959846
    [Abstract] [Full Text] [Related]

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