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133 related items for PubMed ID: 16083988

  • 1. Studies on the targeted delivery of the antifibrogenic compound mycophenolic acid to the hepatic stellate cell.
    Greupink R, Bakker HI, Reker-Smit C, van Loenen-Weemaes AM, Kok RJ, Meijer DK, Beljaars L, Poelstra K.
    J Hepatol; 2005 Nov; 43(5):884-92. PubMed ID: 16083988
    [Abstract] [Full Text] [Related]

  • 2. The antiproliferative drug doxorubicin inhibits liver fibrosis in bile duct-ligated rats and can be selectively delivered to hepatic stellate cells in vivo.
    Greupink R, Bakker HI, Bouma W, Reker-Smit C, Meijer DK, Beljaars L, Poelstra K.
    J Pharmacol Exp Ther; 2006 May; 317(2):514-21. PubMed ID: 16439617
    [Abstract] [Full Text] [Related]

  • 3. Pharmacokinetics of a hepatic stellate cell-targeted doxorubicin construct in bile duct-ligated rats.
    Greupink R, Reker-Smit C, Proost JH, van Loenen Weemaes AM, de Hooge M, Poelstra K, Beljaars L.
    Biochem Pharmacol; 2007 May 01; 73(9):1455-62. PubMed ID: 17239825
    [Abstract] [Full Text] [Related]

  • 4. Effects of a new bioactive lipid-based drug carrier on cultured hepatic stellate cells and liver fibrosis in bile duct-ligated rats.
    Adrian JE, Poelstra K, Scherphof GL, Meijer DK, van Loenen-Weemaes AM, Reker-Smit C, Morselt HW, Zwiers P, Kamps JA.
    J Pharmacol Exp Ther; 2007 May 01; 321(2):536-43. PubMed ID: 17314198
    [Abstract] [Full Text] [Related]

  • 5. Albumin modified with mannose 6-phosphate: A potential carrier for selective delivery of antifibrotic drugs to rat and human hepatic stellate cells.
    Beljaars L, Molema G, Weert B, Bonnema H, Olinga P, Groothuis GM, Meijer DK, Poelstra K.
    Hepatology; 1999 May 01; 29(5):1486-93. PubMed ID: 10216133
    [Abstract] [Full Text] [Related]

  • 6. Local inhibition of liver fibrosis by specific delivery of a platelet-derived growth factor kinase inhibitor to hepatic stellate cells.
    Gonzalo T, Beljaars L, van de Bovenkamp M, Temming K, van Loenen AM, Reker-Smit C, Meijer DK, Lacombe M, Opdam F, Kéri G, Orfi L, Poelstra K, Kok RJ.
    J Pharmacol Exp Ther; 2007 Jun 01; 321(3):856-65. PubMed ID: 17369283
    [Abstract] [Full Text] [Related]

  • 7. Reduction of fibrogenesis by selective delivery of a Rho kinase inhibitor to hepatic stellate cells in mice.
    van Beuge MM, Prakash J, Lacombe M, Gosens R, Post E, Reker-Smit C, Beljaars L, Poelstra K.
    J Pharmacol Exp Ther; 2011 Jun 01; 337(3):628-35. PubMed ID: 21383021
    [Abstract] [Full Text] [Related]

  • 8. Interaction of targeted liposomes with primary cultured hepatic stellate cells: Involvement of multiple receptor systems.
    Adrian JE, Poelstra K, Scherphof GL, Molema G, Meijer DK, Reker-Smit C, Morselt HW, Kamps JA.
    J Hepatol; 2006 Mar 01; 44(3):560-7. PubMed ID: 16368158
    [Abstract] [Full Text] [Related]

  • 9. Hepatic stellate cell-targeted delivery of M6P-HSA-glycyrrhetinic acid attenuates hepatic fibrogenesis in a bile duct ligation rat model.
    Luk JM, Zhang QS, Lee NP, Wo JY, Leung PP, Liu LX, Hu MY, Cheung KF, Hui CK, Lau GK, Fan ST.
    Liver Int; 2007 May 01; 27(4):548-57. PubMed ID: 17403195
    [Abstract] [Full Text] [Related]

  • 10. Ribozymes against TGFbeta1 reverse character of activated hepatic stellate cells in vitro and inhibit liver fibrosis in rats.
    Song YH, Chen XL, Kong XJ, Liu NZ, Li W, Wu XL, Lin JS, Jin YX.
    J Gene Med; 2005 Jul 01; 7(7):965-76. PubMed ID: 15772939
    [Abstract] [Full Text] [Related]

  • 11. Induced hypothyroidism accelerates the regression of liver fibrosis in rats.
    Bruck R, Weiss S, Traister A, Zvibel I, Aeed H, Halpern Z, Oren R.
    J Gastroenterol Hepatol; 2007 Dec 01; 22(12):2189-94. PubMed ID: 18031379
    [Abstract] [Full Text] [Related]

  • 12. Peptide-modified albumin carrier explored as a novel strategy for a cell-specific delivery of interferon gamma to treat liver fibrosis.
    Bansal R, Prakash J, de Ruijter M, Beljaars L, Poelstra K.
    Mol Pharm; 2011 Oct 03; 8(5):1899-909. PubMed ID: 21800888
    [Abstract] [Full Text] [Related]

  • 13. Role of endogenous opioids in modulating HSC activity in vitro and liver fibrosis in vivo.
    De Minicis S, Candelaresi C, Marzioni M, Saccomano S, Roskams T, Casini A, Risaliti A, Salzano R, Cautero N, di Francesco F, Benedetti A, Svegliati-Baroni G.
    Gut; 2008 Mar 03; 57(3):352-64. PubMed ID: 17989109
    [Abstract] [Full Text] [Related]

  • 14. Targeting 15d-prostaglandin J2 to hepatic stellate cells: two options evaluated.
    Hagens WI, Mattos A, Greupink R, de Jager-Krikken A, Reker-Smit C, van Loenen-Weemaes A, Gouw IA, Poelstra K, Beljaars L.
    Pharm Res; 2007 Mar 03; 24(3):566-74. PubMed ID: 17245650
    [Abstract] [Full Text] [Related]

  • 15. Partial hepatectomy-induced regeneration accelerates reversion of liver fibrosis involving participation of hepatic stellate cells.
    Suárez-Cuenca JA, Chagoya de Sánchez V, Aranda-Fraustro A, Sánchez-Sevilla L, Martínez-Pérez L, Hernández-Muñoz R.
    Exp Biol Med (Maywood); 2008 Jul 03; 233(7):827-39. PubMed ID: 18445764
    [Abstract] [Full Text] [Related]

  • 16. Mannose 6-phosphate-modified bovine serum albumin nanoparticles for controlled and targeted delivery of sodium ferulate for treatment of hepatic fibrosis.
    Li FQ, Su H, Chen X, Qin XJ, Liu JY, Zhu QG, Hu JH.
    J Pharm Pharmacol; 2009 Sep 03; 61(9):1155-61. PubMed ID: 19703364
    [Abstract] [Full Text] [Related]

  • 17. Mannose-6-phosphate/insulin-Like growth factor-II receptors may represent a target for the selective delivery of mycophenolic acid to fibrogenic cells.
    Greupink R, Bakker HI, van Goor H, de Borst MH, Beljaars L, Poelstra K.
    Pharm Res; 2006 Aug 03; 23(8):1827-34. PubMed ID: 16850269
    [Abstract] [Full Text] [Related]

  • 18. Nicotinamide induces apoptosis and reduces collagen I and pro-inflammatory cytokines expression in rat hepatic stellate cells.
    Traister A, Breitman I, Bar-Lev E, Zvibel I, Harel A, Halpern Z, Oren R.
    Scand J Gastroenterol; 2005 Oct 03; 40(10):1226-34. PubMed ID: 16165703
    [Abstract] [Full Text] [Related]

  • 19. Expression of extracellular matrix genes in cultured hepatic oval cells: an origin of hepatic stellate cells through transforming growth factor beta?
    Wang P, Liu T, Cong M, Wu X, Bai Y, Yin C, An W, Wang B, Jia J, You H.
    Liver Int; 2009 Apr 03; 29(4):575-84. PubMed ID: 19323784
    [Abstract] [Full Text] [Related]

  • 20. [Effects of bone morphogenic proteins-7 on production of collagen from hepatocytes and hepatic stellate cells during liver fibrosis].
    Yang L, Yang CQ, Yuan M, Wang SL, Chang YZ, Xu LJ, Zhang ZJ.
    Zhonghua Yi Xue Za Zhi; 2009 Feb 17; 89(6):419-22. PubMed ID: 19567125
    [Abstract] [Full Text] [Related]

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