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Journal Abstract Search

111 related items for PubMed ID: 16087334

  • 1. Novel inhibitors of the hepatitis C virus NS3 proteinase.
    Bennett F, Liu YT, Saksena AK, Arasappan A, Butkiewicz N, Dasmahapatra B, Pichardo JS, Njoroge FG, Patel NM, Huang Y, Yang X.
    Bioorg Med Chem Lett; 2005 Oct 01; 15(19):4275-8. PubMed ID: 16087334
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  • 4. Novel potent hepatitis C virus NS3 serine protease inhibitors derived from proline-based macrocycles.
    Chen KX, Njoroge FG, Arasappan A, Venkatraman S, Vibulbhan B, Yang W, Parekh TN, Pichardo J, Prongay A, Cheng KC, Butkiewicz N, Yao N, Madison V, Girijavallabhan V.
    J Med Chem; 2006 Feb 09; 49(3):995-1005. PubMed ID: 16451065
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  • 5. P2-P4 macrocyclic inhibitors of hepatitis C virus NS3-4A serine protease.
    Arasappan A, Njoroge FG, Chen KX, Venkatraman S, Parekh TN, Gu H, Pichardo J, Butkiewicz N, Prongay A, Madison V, Girijavallabhan V.
    Bioorg Med Chem Lett; 2006 Aug 01; 16(15):3960-5. PubMed ID: 16730985
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  • 8. The N-terminal region of NS3 serine proteinase of hepatitis C virus is important to maintain its enzymatic integrity.
    Mori A, Yuasa S, Yamada K, Nagami Y, Miyamura T.
    Biochem Biophys Res Commun; 1997 Feb 24; 231(3):738-42. PubMed ID: 9070884
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  • 10. Hepatitis C virus NS3-4A serine protease inhibitors: SAR of new P1 derivatives of SCH 503034.
    Bogen S, Arasappan A, Pan W, Ruan S, Padilla A, Saksena AK, Girijavallabhan V, Njoroge FG.
    Bioorg Med Chem Lett; 2008 Jul 15; 18(14):4219-23. PubMed ID: 18547808
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  • 12. Second-generation highly potent and selective inhibitors of the hepatitis C virus NS3 serine protease.
    Chen KX, Nair L, Vibulbhan B, Yang W, Arasappan A, Bogen SL, Venkatraman S, Bennett F, Pan W, Blackman ML, Padilla AI, Prongay A, Cheng KC, Tong X, Shih NY, Njoroge FG.
    J Med Chem; 2009 Mar 12; 52(5):1370-9. PubMed ID: 19196021
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  • 13. Novel 2-oxoimidazolidine-4-carboxylic acid derivatives as hepatitis C virus NS3-4A serine protease inhibitors: synthesis, activity, and X-ray crystal structure of an enzyme inhibitor complex.
    Arasappan A, Njoroge FG, Parekh TN, Yang X, Pichardo J, Butkiewicz N, Prongay A, Yao N, Girijavallabhan V.
    Bioorg Med Chem Lett; 2004 Dec 06; 14(23):5751-5. PubMed ID: 15501035
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  • 14. Phosphorous acid analogs of novel P2-P4 macrocycles as inhibitors of HCV-NS3 protease.
    Pompei M, Francesco ME, Koch U, Liverton NJ, Summa V.
    Bioorg Med Chem Lett; 2009 May 01; 19(9):2574-8. PubMed ID: 19328685
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  • 15. Synthesis and antiviral evaluation of a novel series of homoserine-based inhibitors of the hepatitis C virus NS3/4A serine protease.
    Alexandre FR, Brandt G, Caillet C, Chaves D, Convard T, Derock M, Gloux D, Griffon Y, Lallos L, Leroy F, Liuzzi M, Loi AG, Moulat L, Musiu C, Parsy C, Rahali H, Roques V, Seifer M, Standring D, Surleraux D.
    Bioorg Med Chem Lett; 2015 Sep 15; 25(18):3984-91. PubMed ID: 26231161
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  • 17. Solid phase synthesis of aminoboronic acids: potent inhibitors of the hepatitis C virus NS3 proteinase.
    Dunsdon RM, Greening JR, Jones PS, Jordan S, Wilson FX.
    Bioorg Med Chem Lett; 2000 Jul 17; 10(14):1577-9. PubMed ID: 10915055
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  • 20. Inhibitors of hepatitis C virus NS3/4A: alpha-ketoamide based macrocyclic inhibitors.
    Avolio S, Robertson K, Hernando JI, DiMuzio J, Summa V.
    Bioorg Med Chem Lett; 2009 Apr 15; 19(8):2295-8. PubMed ID: 19285390
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