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Journal Abstract Search

125 related items for PubMed ID: 1608935

  • 1. A molecular mechanism for pyrimidine and purine nucleotide control of aspartate transcarbamoylase.
    Stevens RC, Lipscomb WN.
    Proc Natl Acad Sci U S A; 1992 Jun 15; 89(12):5281-5. PubMed ID: 1608935
    [Abstract] [Full Text] [Related]

  • 2. Structural consequences of effector binding to the T state of aspartate carbamoyltransferase: crystal structures of the unligated and ATP- and CTP-complexed enzymes at 2.6-A resolution.
    Stevens RC, Gouaux JE, Lipscomb WN.
    Biochemistry; 1990 Aug 21; 29(33):7691-701. PubMed ID: 2271528
    [Abstract] [Full Text] [Related]

  • 3. Heterotropic interactions in Escherichia coli aspartate transcarbamylase. Subunit interfaces involved in CTP inhibition and ATP activation.
    Xi XG, van Vliet F, Ladjimi MM, de Wannemaeker B, de Staercke C, Glansdorff N, Piérard A, Cunin R, Hervé G.
    J Mol Biol; 1991 Aug 05; 220(3):789-99. PubMed ID: 1870132
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  • 4. Crystal structures of aspartate carbamoyltransferase ligated with phosphonoacetamide, malonate, and CTP or ATP at 2.8-A resolution and neutral pH.
    Gouaux JE, Stevens RC, Lipscomb WN.
    Biochemistry; 1990 Aug 21; 29(33):7702-15. PubMed ID: 2271529
    [Abstract] [Full Text] [Related]

  • 5. Threonine 82 in the regulatory chain is important for nucleotide affinity and for the allosteric stabilization of Escherichia coli aspartate transcarbamoylase.
    Williams MK, Kantrowitz ER.
    Biochim Biophys Acta; 1998 Dec 08; 1429(1):249-58. PubMed ID: 9920401
    [Abstract] [Full Text] [Related]

  • 6. Site-directed alterations to the geometry of the aspartate transcarbamoylase zinc domain: selective alteration to regulation by heterotropic ligands, isoelectric point, and stability in urea.
    Strang CJ, Wales ME, Brown DM, Wild JR.
    Biochemistry; 1993 Apr 27; 32(16):4156-67. PubMed ID: 8476846
    [Abstract] [Full Text] [Related]

  • 7. The N-terminus of the regulatory chain of Escherichia coli aspartate transcarbamoylase is important for both nucleotide binding and heterotropic effects.
    Sakash JB, Kantrowitz ER.
    Biochemistry; 1998 Jan 06; 37(1):281-8. PubMed ID: 9425049
    [Abstract] [Full Text] [Related]

  • 8. Crystal structure of CTP-ligated T state aspartate transcarbamoylase at 2.5 A resolution: implications for ATCase mutants and the mechanism of negative cooperativity.
    Kosman RP, Gouaux JE, Lipscomb WN.
    Proteins; 1993 Feb 06; 15(2):147-76. PubMed ID: 8441751
    [Abstract] [Full Text] [Related]

  • 9. Heterotropic interactions in aspartate transcarbamoylase: turning allosteric ATP activation into inhibition as a consequence of a single tyrosine to phenylalanine mutation.
    Van Vliet F, Xi XG, De Staercke C, de Wannemaeker B, Jacobs A, Cherfils J, Ladjimi MM, Hervé G, Cunin R.
    Proc Natl Acad Sci U S A; 1991 Oct 15; 88(20):9180-3. PubMed ID: 1924381
    [Abstract] [Full Text] [Related]

  • 10. Application of methyl-TROSY NMR to test allosteric models describing effects of nucleotide binding to aspartate transcarbamoylase.
    Velyvis A, Schachman HK, Kay LE.
    J Mol Biol; 2009 Apr 03; 387(3):540-7. PubMed ID: 19302799
    [Abstract] [Full Text] [Related]

  • 11. A single mutation in the regulatory chain of Escherichia coli aspartate transcarbamoylase results in an extreme T-state structure.
    Williams MK, Stec B, Kantrowitz ER.
    J Mol Biol; 1998 Aug 07; 281(1):121-34. PubMed ID: 9680480
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  • 13. Complex of N-phosphonacetyl-L-aspartate with aspartate carbamoyltransferase. X-ray refinement, analysis of conformational changes and catalytic and allosteric mechanisms.
    Ke HM, Lipscomb WN, Cho YJ, Honzatko RB.
    J Mol Biol; 1988 Dec 05; 204(3):725-47. PubMed ID: 3066911
    [Abstract] [Full Text] [Related]

  • 14. Asymmetry of binding and physical assignments of CTP and ATP sites in aspartate transcarbamoylase.
    Suter P, Rosenbusch JP.
    J Biol Chem; 1977 Nov 25; 252(22):8136-41. PubMed ID: 334776
    [Abstract] [Full Text] [Related]

  • 15. Communication between dissimilar subunits in aspartate transcarbamoylase: effect of inhibitor and activator on the conformation of the catalytic polypeptide chains.
    Hensley P, Schachman HK.
    Proc Natl Acad Sci U S A; 1979 Aug 25; 76(8):3732-6. PubMed ID: 386346
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  • 18. Structural asymmetry in the CTP-liganded form of aspartate carbamoyltransferase from Escherichia coli.
    Kim KH, Pan ZX, Honzatko RB, Ke HM, Lipscomb WN.
    J Mol Biol; 1987 Aug 20; 196(4):853-75. PubMed ID: 3316665
    [Abstract] [Full Text] [Related]

  • 19. The use of alanine scanning mutagenesis to determine the role of the N-terminus of the regulatory chain in the heterotropic mechanism of Escherichia coli aspartate transcarbamoylase.
    Dembowski NJ, Kantrowitz ER.
    Protein Eng; 1994 May 20; 7(5):673-9. PubMed ID: 8073037
    [Abstract] [Full Text] [Related]

  • 20. Intramolecular signal transmission in enterobacterial aspartate transcarbamylases II. Engineering co-operativity and allosteric regulation in the aspartate transcarbamylase of Erwinia herbicola.
    Cunin R, Rani CS, Van Vliet F, Wild JR, Wales M.
    J Mol Biol; 1999 Dec 17; 294(5):1401-11. PubMed ID: 10600394
    [Abstract] [Full Text] [Related]

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