These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

223 related items for PubMed ID: 16107150

  • 1. Synthesis, biological evaluation, and molecular modeling investigation of new chiral fibrates with PPARalpha and PPARgamma agonist activity.
    Pinelli A, Godio C, Laghezza A, Mitro N, Fracchiolla G, Tortorella V, Lavecchia A, Novellino E, Fruchart JC, Staels B, Crestani M, Loiodice F.
    J Med Chem; 2005 Aug 25; 48(17):5509-19. PubMed ID: 16107150
    [Abstract] [Full Text] [Related]

  • 2. Synthesis, biological evaluation, and molecular modeling investigation of chiral phenoxyacetic acid analogues with PPARalpha and PPARgamma agonist activity.
    Fracchiolla G, Laghezza A, Piemontese L, Carbonara G, Lavecchia A, Tortorella P, Crestani M, Novellino E, Loiodice F.
    ChemMedChem; 2007 May 25; 2(5):641-54. PubMed ID: 17357171
    [Abstract] [Full Text] [Related]

  • 3. New 2-aryloxy-3-phenyl-propanoic acids as peroxisome proliferator-activated receptors alpha/gamma dual agonists with improved potency and reduced adverse effects on skeletal muscle function.
    Fracchiolla G, Laghezza A, Piemontese L, Tortorella P, Mazza F, Montanari R, Pochetti G, Lavecchia A, Novellino E, Pierno S, Conte Camerino D, Loiodice F.
    J Med Chem; 2009 Oct 22; 52(20):6382-93. PubMed ID: 19775169
    [Abstract] [Full Text] [Related]

  • 4. Design, synthesis, and biological evaluation of novel constrained meta-substituted phenyl propanoic acids as peroxisome proliferator-activated receptor alpha and gamma dual agonists.
    Suh YG, Kim NJ, Koo BW, Lee KO, Moon SH, Shin DH, Jung JW, Paek SM, Chang DJ, Li F, Kang HJ, Le TV, Chae YN, Shin CY, Kim MK, Lim JI, Ryu JS, Park HJ.
    J Med Chem; 2008 Oct 23; 51(20):6318-33. PubMed ID: 18826205
    [Abstract] [Full Text] [Related]

  • 5. Peroxisome proliferator-activated receptors in vascular biology-molecular mechanisms and clinical implications.
    Touyz RM, Schiffrin EL.
    Vascul Pharmacol; 2006 Jul 23; 45(1):19-28. PubMed ID: 16782410
    [Abstract] [Full Text] [Related]

  • 6.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 7. Design, synthesis, and structural analysis of phenylpropanoic acid-type PPARγ-selective agonists: discovery of reversed stereochemistry-activity relationship.
    Ohashi M, Oyama T, Nakagome I, Satoh M, Nishio Y, Nobusada H, Hirono S, Morikawa K, Hashimoto Y, Miyachi H.
    J Med Chem; 2011 Jan 13; 54(1):331-41. PubMed ID: 21128600
    [Abstract] [Full Text] [Related]

  • 8.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 9. A rapid, homogeneous, fluorescence polarization binding assay for peroxisome proliferator-activated receptors alpha and gamma using a fluorescein-tagged dual PPARalpha/gamma activator.
    Seethala R, Golla R, Ma Z, Zhang H, O'Malley K, Lippy J, Cheng L, Mookhtiar K, Farrelly D, Zhang L, Hariharan N, Cheng PT.
    Anal Biochem; 2007 Apr 15; 363(2):263-74. PubMed ID: 17335769
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and evaluation of azaindole-alpha-alkyloxyphenylpropionic acid analogues as PPARalpha/gamma agonists.
    Cai Z, Feng J, Guo Y, Li P, Shen Z, Chu F, Guo Z.
    Bioorg Med Chem; 2006 Feb 01; 14(3):866-74. PubMed ID: 16249089
    [Abstract] [Full Text] [Related]

  • 11. PAR-5359, a well-balanced PPARalpha/gamma dual agonist, exhibits equivalent antidiabetic and hypolipidemic activities in vitro and in vivo.
    Kim MK, Chae YN, Son MH, Kim SH, Kim JK, Moon HS, Park CS, Bae MH, Kim E, Han T, Choi HH, Shin YA, Ahn BN, Lee CH, Lim JI, Shin CY.
    Eur J Pharmacol; 2008 Oct 24; 595(1-3):119-25. PubMed ID: 18727927
    [Abstract] [Full Text] [Related]

  • 12.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 13. Peroxisome proliferator-activated receptor-alpha,gamma-agonist improves insulin sensitivity and prevents loss of left ventricular function in obese dyslipidemic mice.
    Verreth W, Ganame J, Mertens A, Bernar H, Herregods MC, Holvoet P.
    Arterioscler Thromb Vasc Biol; 2006 Apr 24; 26(4):922-8. PubMed ID: 16456093
    [Abstract] [Full Text] [Related]

  • 14. CoMFA analysis of dual/multiple PPAR activators.
    Shah P, Mittal A, Bharatam PV.
    Eur J Med Chem; 2008 Dec 24; 43(12):2784-91. PubMed ID: 18321611
    [Abstract] [Full Text] [Related]

  • 15. Effects of modifications of the linker in a series of phenylpropanoic acid derivatives: Synthesis, evaluation as PPARalpha/gamma dual agonists, and X-ray crystallographic studies.
    Casimiro-Garcia A, Bigge CF, Davis JA, Padalino T, Pulaski J, Ohren JF, McConnell P, Kane CD, Royer LJ, Stevens KA, Auerbach BJ, Collard WT, McGregor C, Fakhoury SA, Schaum RP, Zhou H.
    Bioorg Med Chem; 2008 May 01; 16(9):4883-907. PubMed ID: 18394907
    [Abstract] [Full Text] [Related]

  • 16. A nonthiazolidinedione peroxisome proliferator-activated receptor α/γ dual agonist CG301360 alleviates insulin resistance and lipid dysregulation in db/db mice.
    Jeong HW, Lee JW, Kim WS, Choe SS, Shin HJ, Lee GY, Shin D, Lee JH, Choi EB, Lee HK, Yon GH, Cho B, Kim HR, Choi SH, Chung YS, Park SB, Chung H, Ro S, Kim JB.
    Mol Pharmacol; 2010 Nov 01; 78(5):877-85. PubMed ID: 20724462
    [Abstract] [Full Text] [Related]

  • 17. Effect of PPARalpha activation of macrophages on the secretion of inflammatory cytokines in cultured adipocytes.
    Murakami K, Bujo H, Unoki H, Saito Y.
    Eur J Pharmacol; 2007 Apr 30; 561(1-3):206-13. PubMed ID: 17320860
    [Abstract] [Full Text] [Related]

  • 18. Synthesis, characterization and biological evaluation of ureidofibrate-like derivatives endowed with peroxisome proliferator-activated receptor activity.
    Porcelli L, Gilardi F, Laghezza A, Piemontese L, Mitro N, Azzariti A, Altieri F, Cervoni L, Fracchiolla G, Giudici M, Guerrini U, Lavecchia A, Montanari R, Di Giovanni C, Paradiso A, Pochetti G, Simone GM, Tortorella P, Crestani M, Loiodice F.
    J Med Chem; 2012 Jan 12; 55(1):37-54. PubMed ID: 22081932
    [Abstract] [Full Text] [Related]

  • 19. In vitro screening of 200 pesticides for agonistic activity via mouse peroxisome proliferator-activated receptor (PPAR)alpha and PPARgamma and quantitative analysis of in vivo induction pathway.
    Takeuchi S, Matsuda T, Kobayashi S, Takahashi T, Kojima H.
    Toxicol Appl Pharmacol; 2006 Dec 15; 217(3):235-44. PubMed ID: 17084873
    [Abstract] [Full Text] [Related]

  • 20. Peroxisome proliferator-activated receptors (PPARs) have multiple binding points that accommodate ligands in various conformations: phenylpropanoic acid-type PPAR ligands bind to PPAR in different conformations, depending on the subtype.
    Kuwabara N, Oyama T, Tomioka D, Ohashi M, Yanagisawa J, Shimizu T, Miyachi H.
    J Med Chem; 2012 Jan 26; 55(2):893-902. PubMed ID: 22185225
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 12.