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Journal Abstract Search


178 related items for PubMed ID: 16112867

  • 1. Polyglutamine-expanded ataxin-3 activates mitochondrial apoptotic pathway by upregulating Bax and downregulating Bcl-xL.
    Chou AH, Yeh TH, Kuo YL, Kao YC, Jou MJ, Hsu CY, Tsai SR, Kakizuka A, Wang HL.
    Neurobiol Dis; 2006 Feb; 21(2):333-45. PubMed ID: 16112867
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  • 2. Polyglutamine-expanded ataxin-7 activates mitochondrial apoptotic pathway of cerebellar neurons by upregulating Bax and downregulating Bcl-x(L).
    Wang HL, Yeh TH, Chou AH, Kuo YL, Luo LJ, He CY, Huang PC, Li AH.
    Cell Signal; 2006 Apr; 18(4):541-52. PubMed ID: 15964171
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  • 3. p53 activation mediates polyglutamine-expanded ataxin-3 upregulation of Bax expression in cerebellar and pontine nuclei neurons.
    Chou AH, Lin AC, Hong KY, Hu SH, Chen YL, Chen JY, Wang HL.
    Neurochem Int; 2011 Feb; 58(2):145-52. PubMed ID: 21092747
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  • 8. HDAC inhibitor sodium butyrate reverses transcriptional downregulation and ameliorates ataxic symptoms in a transgenic mouse model of SCA3.
    Chou AH, Chen SY, Yeh TH, Weng YH, Wang HL.
    Neurobiol Dis; 2011 Feb; 41(2):481-8. PubMed ID: 21047555
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  • 10. Ataxin-3 protects cells against H2O2-induced oxidative stress by enhancing the interaction between Bcl-X(L) and Bax.
    Zhou L, Wang H, Wang P, Ren H, Chen D, Ying Z, Wang G.
    Neuroscience; 2013 Jul 23; 243():14-21. PubMed ID: 23562578
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  • 12. Polyglutamine-expanded ataxin-7 causes cerebellar dysfunction by inducing transcriptional dysregulation.
    Chou AH, Chen CY, Chen SY, Chen WJ, Chen YL, Weng YS, Wang HL.
    Neurochem Int; 2010 Jan 23; 56(2):329-39. PubMed ID: 19909779
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  • 13. Polyglutamine-expanded ataxin-7 decreases nuclear translocation of NF-kappaB p65 and impairs NF-kappaB activity by inhibiting proteasome activity of cerebellar neurons.
    Wang HL, He CY, Chou AH, Yeh TH, Chen YL, Li AH.
    Cell Signal; 2007 Mar 23; 19(3):573-81. PubMed ID: 17005371
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  • 14. Caspase-mediated proteolysis of the polyglutamine disease protein ataxin-3.
    Berke SJ, Schmied FA, Brunt ER, Ellerby LM, Paulson HL.
    J Neurochem; 2004 May 23; 89(4):908-18. PubMed ID: 15140190
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  • 17. ERK- and Akt-dependent neuroprotection by erythropoietin (EPO) against glyoxal-AGEs via modulation of Bcl-xL, Bax, and BAD.
    Shen J, Wu Y, Xu JY, Zhang J, Sinclair SH, Yanoff M, Xu G, Li W, Xu GT.
    Invest Ophthalmol Vis Sci; 2010 Jan 23; 51(1):35-46. PubMed ID: 19628748
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  • 18. Similarities between spinocerebellar ataxia type 7 (SCA7) cell models and human brain: proteins recruited in inclusions and activation of caspase-3.
    Zander C, Takahashi J, El Hachimi KH, Fujigasaki H, Albanese V, Lebre AS, Stevanin G, Duyckaerts C, Brice A.
    Hum Mol Genet; 2001 Oct 15; 10(22):2569-79. PubMed ID: 11709544
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  • 19. Inflammatory genes are upregulated in expanded ataxin-3-expressing cell lines and spinocerebellar ataxia type 3 brains.
    Evert BO, Vogt IR, Kindermann C, Ozimek L, de Vos RA, Brunt ER, Schmitt I, Klockgether T, Wüllner U.
    J Neurosci; 2001 Aug 01; 21(15):5389-96. PubMed ID: 11466410
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  • 20. GDNF protects against aluminum-induced apoptosis in rabbits by upregulating Bcl-2 and Bcl-XL and inhibiting mitochondrial Bax translocation.
    Ghribi O, Herman MM, Forbes MS, DeWitt DA, Savory J.
    Neurobiol Dis; 2001 Oct 01; 8(5):764-73. PubMed ID: 11592846
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