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1015 related items for PubMed ID: 16115952

  • 1. Response of non-small cell lung cancer cells to the inhibitors of phosphatidylinositol 3-kinase/Akt- and MAPK kinase 4/c-Jun NH2-terminal kinase pathways: an effective therapeutic strategy for lung cancer.
    Lee HY, Oh SH, Suh YA, Baek JH, Papadimitrakopoulou V, Huang S, Hong WK.
    Clin Cancer Res; 2005 Aug 15; 11(16):6065-74. PubMed ID: 16115952
    [Abstract] [Full Text] [Related]

  • 2. Effects of insulin-like growth factor binding protein-3 and farnesyltransferase inhibitor SCH66336 on Akt expression and apoptosis in non-small-cell lung cancer cells.
    Lee HY, Moon H, Chun KH, Chang YS, Hassan K, Ji L, Lotan R, Khuri FR, Hong WK.
    J Natl Cancer Inst; 2004 Oct 20; 96(20):1536-48. PubMed ID: 15494604
    [Abstract] [Full Text] [Related]

  • 3. Apoptosis induced by the methanol extract of Salvia miltiorrhiza Bunge in non-small cell lung cancer through PTEN-mediated inhibition of PI3K/Akt pathway.
    Ye YT, Zhong W, Sun P, Wang D, Wang C, Hu LM, Qian JQ.
    J Ethnopharmacol; 2017 Mar 22; 200():107-116. PubMed ID: 28088493
    [Abstract] [Full Text] [Related]

  • 4. Evidence that phosphatidylinositol 3-kinase- and mitogen-activated protein kinase kinase-4/c-Jun NH2-terminal kinase-dependent Pathways cooperate to maintain lung cancer cell survival.
    Lee HY, Srinivas H, Xia D, Lu Y, Superty R, LaPushin R, Gomez-Manzano C, Gal AM, Walsh GL, Force T, Ueki K, Mills GB, Kurie JM.
    J Biol Chem; 2003 Jun 27; 278(26):23630-8. PubMed ID: 12714585
    [Abstract] [Full Text] [Related]

  • 5. Combinatorial therapy with adenoviral-mediated PTEN and a PI3K inhibitor suppresses malignant glioma cell growth in vitro and in vivo by regulating the PI3K/AKT signaling pathway.
    Nan Y, Guo L, Song Y, Wang L, Yu K, Huang Q, Zhong Y.
    J Cancer Res Clin Oncol; 2017 Aug 27; 143(8):1477-1487. PubMed ID: 28401302
    [Abstract] [Full Text] [Related]

  • 6. Apoptosis induced by depsipeptide FK228 coincides with inhibition of survival signaling in lung cancer cells.
    Yu XD, Wang SY, Chen GA, Hou CM, Zhao M, Hong JA, Nguyen DM, Schrump DS.
    Cancer J; 2007 Aug 27; 13(2):105-13. PubMed ID: 17476138
    [Abstract] [Full Text] [Related]

  • 7. Insulin-like growth factor binding protein-3 inhibits the growth of non-small cell lung cancer.
    Lee HY, Chun KH, Liu B, Wiehle SA, Cristiano RJ, Hong WK, Cohen P, Kurie JM.
    Cancer Res; 2002 Jun 15; 62(12):3530-7. PubMed ID: 12068000
    [Abstract] [Full Text] [Related]

  • 8. Distinctive regulation and function of PI 3K/Akt and MAPKs in doxorubicin-induced apoptosis of human lung adenocarcinoma cells.
    Zhao Y, You H, Yang Y, Wei L, Zhang X, Yao L, Fan D, Yu Q.
    J Cell Biochem; 2004 Feb 15; 91(3):621-32. PubMed ID: 14755690
    [Abstract] [Full Text] [Related]

  • 9. The phosphoinositide 3-kinase/Akt pathway: a new target in human renal cell carcinoma therapy.
    Sourbier C, Lindner V, Lang H, Agouni A, Schordan E, Danilin S, Rothhut S, Jacqmin D, Helwig JJ, Massfelder T.
    Cancer Res; 2006 May 15; 66(10):5130-42. PubMed ID: 16707436
    [Abstract] [Full Text] [Related]

  • 10. [Combined inhibition of PI3K and MEK has synergistic inhibitory effect on the proliferation of cisplatin-resistant ovarian cancer cells].
    Liu Y, Chen X, Luo Z.
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi; 2014 Jun 15; 30(6):592-6. PubMed ID: 24909280
    [Abstract] [Full Text] [Related]

  • 11. MKP1 repression is required for the chemosensitizing effects of NF-kappaB and PI3K inhibitors to cisplatin in non-small cell lung cancer.
    Cortes-Sempere M, Chattopadhyay S, Rovira A, Rodriguez-Fanjul V, Belda-Iniesta C, Tapia M, Cejas P, Machado-Pinilla R, Manguan-García C, Sánchez-Pérez I, Nistal M, Moratilla C, de Castro-Carpeño J, Gonzalez-Barón M, Albanell J, Perona R.
    Cancer Lett; 2009 Dec 28; 286(2):206-16. PubMed ID: 19553005
    [Abstract] [Full Text] [Related]

  • 12. Combined inhibition of MEK and PI3K pathways overcomes acquired resistance to EGFR-TKIs in non-small cell lung cancer.
    Sato H, Yamamoto H, Sakaguchi M, Shien K, Tomida S, Shien T, Ikeda H, Hatono M, Torigoe H, Namba K, Yoshioka T, Kurihara E, Ogoshi Y, Takahashi Y, Soh J, Toyooka S.
    Cancer Sci; 2018 Oct 28; 109(10):3183-3196. PubMed ID: 30098066
    [Abstract] [Full Text] [Related]

  • 13. Inhibition of phosphatidylinositol 3-kinase/Akt and histone deacetylase activity induces apoptosis in non-small cell lung cancer in vitro and in vivo.
    Denlinger CE, Rundall BK, Jones DR.
    J Thorac Cardiovasc Surg; 2005 Nov 28; 130(5):1422-9. PubMed ID: 16256798
    [Abstract] [Full Text] [Related]

  • 14. MicroRNA-92a promotes epithelial-mesenchymal transition through activation of PTEN/PI3K/AKT signaling pathway in non-small cell lung cancer metastasis.
    Lu C, Shan Z, Hong J, Yang L.
    Int J Oncol; 2017 Jul 28; 51(1):235-244. PubMed ID: 28534966
    [Abstract] [Full Text] [Related]

  • 15. Blocking the PI3K/AKT and MEK/ERK signaling pathways can overcome gefitinib-resistance in non-small cell lung cancer cell lines.
    Li H, Schmid-Bindert G, Wang D, Zhao Y, Yang X, Su B, Zhou C.
    Adv Med Sci; 2011 Jul 28; 56(2):275-84. PubMed ID: 22037177
    [Abstract] [Full Text] [Related]

  • 16. LY294002 and metformin cooperatively enhance the inhibition of growth and the induction of apoptosis of ovarian cancer cells.
    Li C, Liu VW, Chan DW, Yao KM, Ngan HY.
    Int J Gynecol Cancer; 2012 Jan 28; 22(1):15-22. PubMed ID: 22080879
    [Abstract] [Full Text] [Related]

  • 17. Targeting heat shock protein 90 with CUDC-305 overcomes erlotinib resistance in non-small cell lung cancer.
    Bao R, Lai CJ, Wang DG, Qu H, Yin L, Zifcak B, Tao X, Wang J, Atoyan R, Samson M, Forrester J, Xu GX, DellaRocca S, Borek M, Zhai HX, Cai X, Qian C.
    Mol Cancer Ther; 2009 Dec 28; 8(12):3296-306. PubMed ID: 19952121
    [Abstract] [Full Text] [Related]

  • 18. Antitumor activity of selective MEK1/2 inhibitor AZD6244 in combination with PI3K/mTOR inhibitor BEZ235 in gefitinib-resistant NSCLC xenograft models.
    Qu Y, Wu X, Yin Y, Yang Y, Ma D, Li H.
    J Exp Clin Cancer Res; 2014 Jun 17; 33(1):52. PubMed ID: 24939055
    [Abstract] [Full Text] [Related]

  • 19. PI3K/PTEN/AKT signaling regulates prostate tumor angiogenesis.
    Fang J, Ding M, Yang L, Liu LZ, Jiang BH.
    Cell Signal; 2007 Dec 17; 19(12):2487-97. PubMed ID: 17826033
    [Abstract] [Full Text] [Related]

  • 20. Different signaling pathways are involved in cardiomyocyte survival induced by a Trypanosoma cruzi glycoprotein.
    Aoki Mdel P, Cano RC, Pellegrini AV, Tanos T, Guiñazú NL, Coso OA, Gea S.
    Microbes Infect; 2006 Jun 17; 8(7):1723-31. PubMed ID: 16815723
    [Abstract] [Full Text] [Related]

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