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Journal Abstract Search

137 related items for PubMed ID: 16117535

  • 1. Chimeric (alpha/beta + alpha)-peptide ligands for the BH3-recognition cleft of Bcl-XL: critical role of the molecular scaffold in protein surface recognition.
    Sadowsky JD, Schmitt MA, Lee HS, Umezawa N, Wang S, Tomita Y, Gellman SH.
    J Am Chem Soc; 2005 Aug 31; 127(34):11966-8. PubMed ID: 16117535
    [Abstract] [Full Text] [Related]

  • 2. (alpha/beta+alpha)-peptide antagonists of BH3 domain/Bcl-x(L) recognition: toward general strategies for foldamer-based inhibition of protein-protein interactions.
    Sadowsky JD, Fairlie WD, Hadley EB, Lee HS, Umezawa N, Nikolovska-Coleska Z, Wang S, Huang DC, Tomita Y, Gellman SH.
    J Am Chem Soc; 2007 Jan 10; 129(1):139-54. PubMed ID: 17199293
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  • 3. Exploration of backbone space in foldamers containing alpha- and beta-amino acid residues: developing protease-resistant oligomers that bind tightly to the BH3-recognition cleft of Bcl-xL.
    Sadowsky JD, Murray JK, Tomita Y, Gellman SH.
    Chembiochem; 2007 May 25; 8(8):903-16. PubMed ID: 17503422
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  • 4. New helical foldamers: heterogeneous backbones with 1:2 and 2:1 alpha:beta-amino acid residue patterns.
    Schmitt MA, Choi SH, Guzei IA, Gellman SH.
    J Am Chem Soc; 2006 Apr 12; 128(14):4538-9. PubMed ID: 16594667
    [Abstract] [Full Text] [Related]

  • 5. Chelerythrine and sanguinarine dock at distinct sites on BclXL that are not the classic BH3 binding cleft.
    Zhang YH, Bhunia A, Wan KF, Lee MC, Chan SL, Yu VC, Mok YK.
    J Mol Biol; 2006 Dec 01; 364(3):536-49. PubMed ID: 17011577
    [Abstract] [Full Text] [Related]

  • 6. Exploration of structure--activity relationships among foldamer ligands for a specific protein binding site via parallel and split-and-mix library synthesis.
    Murray JK, Sadowsky JD, Scalf M, Smith LM, Tomita Y, Gellman SH.
    J Comb Chem; 2008 Dec 01; 10(2):204-15. PubMed ID: 18275161
    [Abstract] [Full Text] [Related]

  • 7. Terphenyl-Based Bak BH3 alpha-helical proteomimetics as low-molecular-weight antagonists of Bcl-xL.
    Yin H, Lee GI, Sedey KA, Kutzki O, Park HS, Orner BP, Ernst JT, Wang HG, Sebti SM, Hamilton AD.
    J Am Chem Soc; 2005 Jul 27; 127(29):10191-6. PubMed ID: 16028929
    [Abstract] [Full Text] [Related]

  • 8. Structure of the BH3 domains from the p53-inducible BH3-only proteins Noxa and Puma in complex with Mcl-1.
    Day CL, Smits C, Fan FC, Lee EF, Fairlie WD, Hinds MG.
    J Mol Biol; 2008 Jul 25; 380(5):958-71. PubMed ID: 18589438
    [Abstract] [Full Text] [Related]

  • 9. Residue-based control of helix shape in beta-peptide oligomers.
    Appella DH, Christianson LA, Klein DA, Powell DR, Huang X, Barchi JJ, Gellman SH.
    Nature; 1997 May 22; 387(6631):381-4. PubMed ID: 9163422
    [Abstract] [Full Text] [Related]

  • 10. Paralog-selective ligands for bcl-2 proteins.
    Gemperli AC, Rutledge SE, Maranda A, Schepartz A.
    J Am Chem Soc; 2005 Feb 16; 127(6):1596-7. PubMed ID: 15700967
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and structure of alpha/delta-hybrid peptides--access to novel helix patterns in foldamers.
    Sharma GV, Babu BS, Ramakrishna KV, Nagendar P, Kunwar AC, Schramm P, Baldauf C, Hofmann HJ.
    Chemistry; 2009 Feb 16; 15(22):5552-66. PubMed ID: 19353607
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  • 16. Heat-induced dimerization of BCL-xL through alpha-helix swapping.
    Denisov AY, Sprules T, Fraser J, Kozlov G, Gehring K.
    Biochemistry; 2007 Jan 23; 46(3):734-40. PubMed ID: 17223694
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  • 17. Transfer-NMR and docking studies identify the binding of the peptide derived from activating transcription factor 4 to protein ubiquitin ligase beta-TrCP. Competition STD-NMR with beta-catenin.
    Pons J, Evrard-Todeschi N, Bertho G, Gharbi-Benarous J, Tanchou V, Benarous R, Girault JP.
    Biochemistry; 2008 Jan 08; 47(1):14-29. PubMed ID: 18052253
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  • 18. Peptides as transmembrane segments: decrypting the determinants for helix-helix interactions in membrane proteins.
    Rath A, Johnson RM, Deber CM.
    Biopolymers; 2007 Jan 08; 88(2):217-32. PubMed ID: 17206630
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  • 20. Photocontrollable peptide-based switches target the anti-apoptotic protein Bcl-xL.
    Kneissl S, Loveridge EJ, Williams C, Crump MP, Allemann RK.
    Chembiochem; 2008 Dec 15; 9(18):3046-54. PubMed ID: 19012295
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