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Journal Abstract Search

274 related items for PubMed ID: 16120637

  • 1. A simple dual selection for functionally active mutants of Plasmodium falciparum dihydrofolate reductase with improved solubility.
    Japrung D, Chusacultanachai S, Yuvaniyama J, Wilairat P, Yuthavong Y.
    Protein Eng Des Sel; 2005 Oct; 18(10):457-64. PubMed ID: 16120637
    [Abstract] [Full Text] [Related]

  • 2. The role of tryptophan-48 in catalysis and binding of inhibitors of Plasmodium falciparum dihydrofolate reductase.
    Kamchonwongpaisan S, Vanichtanankul J, Taweechai S, Chitnumsub P, Yuthavong Y.
    Int J Parasitol; 2007 Jun; 37(7):787-93. PubMed ID: 17320089
    [Abstract] [Full Text] [Related]

  • 3. Plasmodium falciparum: asparagine mutant at residue 108 of dihydrofolate reductase is an optimal antifolate-resistant single mutant.
    Sirawaraporn W, Yongkiettrakul S, Sirawaraporn R, Yuthavong Y, Santi DV.
    Exp Parasitol; 1997 Nov; 87(3):245-52. PubMed ID: 9371090
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  • 4. Stoichiometric selection of tight-binding inhibitors by wild-type and mutant forms of malarial (Plasmodium falciparum) dihydrofolate reductase.
    Kamchonwongpaisan S, Vanichtanankul J, Tarnchompoo B, Yuvaniyama J, Taweechai S, Yuthavong Y.
    Anal Chem; 2005 Mar 01; 77(5):1222-7. PubMed ID: 15732900
    [Abstract] [Full Text] [Related]

  • 5. Novel alleles of Plasmodium falciparum dhfr that confer resistance to chlorcycloguanil.
    Hunt SY, Rezvani BB, Sibley CH.
    Mol Biochem Parasitol; 2005 Jan 01; 139(1):25-32. PubMed ID: 15610816
    [Abstract] [Full Text] [Related]

  • 6. Novel antifolate resistant mutations of Plasmodium falciparum dihydrofolate reductase selected in Escherichia coli.
    Chusacultanachai S, Thiensathit P, Tarnchompoo B, Sirawaraporn W, Yuthavong Y.
    Mol Biochem Parasitol; 2002 Mar 01; 120(1):61-72. PubMed ID: 11849706
    [Abstract] [Full Text] [Related]

  • 7. Subunit complementation of thymidylate synthase in Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase.
    Chanama M, Chitnumsub P, Yuthavong Y.
    Mol Biochem Parasitol; 2005 Jan 01; 139(1):83-90. PubMed ID: 15610822
    [Abstract] [Full Text] [Related]

  • 8. In silico screening against wild-type and mutant Plasmodium falciparum dihydrofolate reductase.
    Fogel GB, Cheung M, Pittman E, Hecht D.
    J Mol Graph Model; 2008 Apr 01; 26(7):1145-52. PubMed ID: 18037315
    [Abstract] [Full Text] [Related]

  • 9. Selection of drug resistant mutants from random library of Plasmodium falciparum dihydrofolate reductase in Plasmodium berghei model.
    Tipsuwan W, Srichairatanakool S, Kamchonwongpaisan S, Yuthavong Y, Uthaipibull C.
    Malar J; 2011 May 10; 10():119. PubMed ID: 21554743
    [Abstract] [Full Text] [Related]

  • 10. 3D-QSAR analysis of cycloguanil derivatives as inhibitors of A16V + S108T mutant Plasmodium falciparum dihydrofolate reductase enzyme.
    Adane L, Bharatam PV.
    J Mol Graph Model; 2009 Nov 10; 28(4):357-67. PubMed ID: 19796975
    [Abstract] [Full Text] [Related]

  • 11. Target guided synthesis of 5-benzyl-2,4-diamonopyrimidines: their antimalarial activities and binding affinities to wild type and mutant dihydrofolate reductases from Plasmodium falciparum.
    Sirichaiwat C, Intaraudom C, Kamchonwongpaisan S, Vanichtanankul J, Thebtaranonth Y, Yuthavong Y.
    J Med Chem; 2004 Jan 15; 47(2):345-54. PubMed ID: 14711307
    [Abstract] [Full Text] [Related]

  • 12. Shape- and chemical feature-based 3D-pharmacophore model generation and virtual screening: identification of potential leads for P. falciparum DHFR enzyme inhibition.
    Adane L, Patel DS, Bharatam PV.
    Chem Biol Drug Des; 2010 Jan 15; 75(1):115-26. PubMed ID: 19895504
    [Abstract] [Full Text] [Related]

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  • 14. Inhibitors of multiple mutants of Plasmodium falciparum dihydrofolate reductase and their antimalarial activities.
    Kamchonwongpaisan S, Quarrell R, Charoensetakul N, Ponsinet R, Vilaivan T, Vanichtanankul J, Tarnchompoo B, Sirawaraporn W, Lowe G, Yuthavong Y.
    J Med Chem; 2004 Jan 29; 47(3):673-80. PubMed ID: 14736247
    [Abstract] [Full Text] [Related]

  • 15. [Gene point mutation in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum].
    Zhang ZX, Yang YM, Liu H.
    Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi; 2001 Jan 29; 19(2):87-9. PubMed ID: 12571992
    [Abstract] [Full Text] [Related]

  • 16. QSAR using evolved neural networks for the inhibition of mutant PfDHFR by pyrimethamine derivatives.
    Hecht D, Cheung M, Fogel GB.
    Biosystems; 2008 Apr 29; 92(1):10-5. PubMed ID: 18160210
    [Abstract] [Full Text] [Related]

  • 17. Improving protein solubility: the use of the Escherichia coli dihydrofolate reductase gene as a fusion reporter.
    Liu JW, Boucher Y, Stokes HW, Ollis DL.
    Protein Expr Purif; 2006 May 29; 47(1):258-63. PubMed ID: 16403649
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  • 20. Insights into antifolate resistance from malarial DHFR-TS structures.
    Yuvaniyama J, Chitnumsub P, Kamchonwongpaisan S, Vanichtanankul J, Sirawaraporn W, Taylor P, Walkinshaw MD, Yuthavong Y.
    Nat Struct Biol; 2003 May 29; 10(5):357-65. PubMed ID: 12704428
    [Abstract] [Full Text] [Related]

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