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387 related items for PubMed ID: 16123451

  • 1. Increased replication of human cytomegalovirus in retinal pigment epithelial cells by valproic acid depends on histone deacetylase inhibition.
    Michaelis M, Suhan T, Reinisch A, Reisenauer A, Fleckenstein C, Eikel D, Gümbel H, Doerr HW, Nau H, Cinatl J.
    Invest Ophthalmol Vis Sci; 2005 Sep; 46(9):3451-7. PubMed ID: 16123451
    [Abstract] [Full Text] [Related]

  • 2. Valproic acid interferes with antiviral treatment in human cytomegalovirus-infected endothelial cells.
    Michaelis M, Ha TA, Doerr HW, Cinatl J.
    Cardiovasc Res; 2008 Feb 01; 77(3):544-50. PubMed ID: 18006438
    [Abstract] [Full Text] [Related]

  • 3. Increased human cytomegalovirus replication in fibroblasts after treatment with therapeutical plasma concentrations of valproic acid.
    Michaelis M, Köhler N, Reinisch A, Eikel D, Gravemann U, Doerr HW, Nau H, Cinatl J.
    Biochem Pharmacol; 2004 Aug 01; 68(3):531-8. PubMed ID: 15242819
    [Abstract] [Full Text] [Related]

  • 4. Additive effects of histone deacetylase inhibitors and amphetamine on histone H4 acetylation, cAMP responsive element binding protein phosphorylation and DeltaFosB expression in the striatum and locomotor sensitization in mice.
    Shen HY, Kalda A, Yu L, Ferrara J, Zhu J, Chen JF.
    Neuroscience; 2008 Dec 02; 157(3):644-55. PubMed ID: 18848971
    [Abstract] [Full Text] [Related]

  • 5. Cytomegalovirus replication in human retinal pigment epithelial cells. Altered expression of viral early proteins.
    Detrick B, Rhame J, Wang Y, Nagineni CN, Hooks JJ.
    Invest Ophthalmol Vis Sci; 1996 Apr 02; 37(5):814-25. PubMed ID: 8603866
    [Abstract] [Full Text] [Related]

  • 6. Teratogenic effects mediated by inhibition of histone deacetylases: evidence from quantitative structure activity relationships of 20 valproic acid derivatives.
    Eikel D, Lampen A, Nau H.
    Chem Res Toxicol; 2006 Feb 02; 19(2):272-8. PubMed ID: 16485903
    [Abstract] [Full Text] [Related]

  • 7. Novel targets for valproic acid: up-regulation of melatonin receptors and neurotrophic factors in C6 glioma cells.
    Castro LM, Gallant M, Niles LP.
    J Neurochem; 2005 Dec 02; 95(5):1227-36. PubMed ID: 16313512
    [Abstract] [Full Text] [Related]

  • 8. p21Waf1/Cip1 is a common target induced by short-chain fatty acid HDAC inhibitors (valproic acid, tributyrin and sodium butyrate) in neuroblastoma cells.
    Rocchi P, Tonelli R, Camerin C, Purgato S, Fronza R, Bianucci F, Guerra F, Pession A, Ferreri AM.
    Oncol Rep; 2005 Jun 02; 13(6):1139-44. PubMed ID: 15870934
    [Abstract] [Full Text] [Related]

  • 9. Induction of osteogenic differentiation of human mesenchymal stem cells by histone deacetylase inhibitors.
    Cho HH, Park HT, Kim YJ, Bae YC, Suh KT, Jung JS.
    J Cell Biochem; 2005 Oct 15; 96(3):533-42. PubMed ID: 16088945
    [Abstract] [Full Text] [Related]

  • 10. Pharmacologic resuscitation: cell protective mechanisms of histone deacetylase inhibition in lethal hemorrhagic shock.
    Butt MU, Sailhamer EA, Li Y, Liu B, Shuja F, Velmahos GC, DeMoya M, King DR, Alam HB.
    J Surg Res; 2009 Oct 15; 156(2):290-6. PubMed ID: 19665733
    [Abstract] [Full Text] [Related]

  • 11. S-2-pentyl-4-pentynoic hydroxamic acid and its metabolite s-2-pentyl-4-pentynoic acid in the NMRI-exencephaly-mouse model: pharmacokinetic profiles, teratogenic effects, and histone deacetylase inhibition abilities of further valproic acid hydroxamates and amides.
    Eikel D, Hoffmann K, Zoll K, Lampen A, Nau H.
    Drug Metab Dispos; 2006 Apr 15; 34(4):612-20. PubMed ID: 16415118
    [Abstract] [Full Text] [Related]

  • 12. Valproic acid, a histone deacetylase inhibitor, is an antagonist for oncolytic adenoviral gene therapy.
    Höti N, Chowdhury W, Hsieh JT, Sachs MD, Lupold SE, Rodriguez R.
    Mol Ther; 2006 Dec 15; 14(6):768-78. PubMed ID: 16990052
    [Abstract] [Full Text] [Related]

  • 13. The histone deacetylase inhibitors suberoylanilide hydroxamic (Vorinostat) and valproic acid induce irreversible and MDR1-independent resistance in human colon cancer cells.
    Fedier A, Dedes KJ, Imesch P, Von Bueren AO, Fink D.
    Int J Oncol; 2007 Sep 15; 31(3):633-41. PubMed ID: 17671692
    [Abstract] [Full Text] [Related]

  • 14. Lysophosphatidic acid receptor signaling in mammalian retinal pigment epithelial cells.
    Thoreson WB, Ryan JS, Shi C, Kelly ME, Bryson EJ, Toews ML, Ediger TL, Chacko DM.
    Invest Ophthalmol Vis Sci; 2002 Jul 15; 43(7):2450-61. PubMed ID: 12091450
    [Abstract] [Full Text] [Related]

  • 15. Hepatoprotection and lethality rescue by histone deacetylase inhibitor valproic acid in fatal hemorrhagic shock.
    Gonzales ER, Chen H, Munuve RM, Mehrani T, Nadel A, Koustova E.
    J Trauma; 2008 Sep 15; 65(3):554-65. PubMed ID: 18784568
    [Abstract] [Full Text] [Related]

  • 16. Histone deacetylase inhibitors induce apoptosis, histone hyperacetylation and up-regulation of gene transcription in Schistosoma mansoni.
    Dubois F, Caby S, Oger F, Cosseau C, Capron M, Grunau C, Dissous C, Pierce RJ.
    Mol Biochem Parasitol; 2009 Nov 15; 168(1):7-15. PubMed ID: 19538992
    [Abstract] [Full Text] [Related]

  • 17. Inhibition of histone deacetylase activity increases chromosomal instability by the aberrant regulation of mitotic checkpoint activation.
    Shin HJ, Baek KH, Jeon AH, Kim SJ, Jang KL, Sung YC, Kim CM, Lee CW.
    Oncogene; 2003 Jun 19; 22(25):3853-8. PubMed ID: 12813458
    [Abstract] [Full Text] [Related]

  • 18. Inhibition of the ERK phosphorylation plays a role in terbinafine-induced p21 up-regulation and DNA synthesis inhibition in human vascular endothelial cells.
    Ho PY, Hsu SP, Liang YC, Kuo ML, Ho YS, Lee WS.
    Toxicol Appl Pharmacol; 2008 May 15; 229(1):86-93. PubMed ID: 18272192
    [Abstract] [Full Text] [Related]

  • 19. Valproic acid exhibits biphasic effects on apoptotic cell death of activated lymphocytes through differential modulation of multiple signaling pathways.
    Chen Q, Ouyang DY, Geng M, Xu LH, Zhang YT, Wang FP, He XH.
    J Immunotoxicol; 2011 May 15; 8(3):210-8. PubMed ID: 21457087
    [Abstract] [Full Text] [Related]

  • 20. New sulfurated derivatives of valproic acid with enhanced histone deacetylase inhibitory activity.
    Perrino E, Cappelletti G, Tazzari V, Giavini E, Del Soldato P, Sparatore A.
    Bioorg Med Chem Lett; 2008 Mar 15; 18(6):1893-7. PubMed ID: 18294844
    [Abstract] [Full Text] [Related]


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