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Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

187 related items for PubMed ID: 16140009

  • 21. 1'-Benzyl-3,4-dihydrospiro[2H-1- benzothiopyran-2,4'-piperidine] (spipethiane), a potent and highly selective sigma1 ligand.
    Quaglia W, Giannella M, Piergentili A, Pigini M, Brasili L, Di Toro R, Rossetti L, Spampinato S, Melchiorre C.
    J Med Chem; 1998 May 07; 41(10):1557-60. PubMed ID: 9572880
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  • 22. A medicinal-chemistry-guided approach to selective and druglike sigma 1 ligands.
    Corbera J, Vaño D, Martínez D, Vela JM, Zamanillo D, Dordal A, Andreu F, Hernandez E, Perez R, Escriche M, Salgado L, Yeste S, Serafini MT, Pascual R, Alegre J, Calvet MC, Cano N, Carro M, Buschmann H, Holenz J.
    ChemMedChem; 2006 Jan 07; 1(1):140-54. PubMed ID: 16892345
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  • 24. Pharmacological and metabolic characterisation of the potent sigma1 receptor ligand 1'-benzyl-3-methoxy-3H-spiro[[2]benzofuran-1,4'-piperidine].
    Wiese C, Grosse Maestrup E, Schepmann D, Vela JM, Holenz J, Buschmann H, Wünsch B.
    J Pharm Pharmacol; 2009 May 07; 61(5):631-40. PubMed ID: 19406002
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  • 25. Synthesis of spirocyclic sigma1 receptor ligands as potential PET radiotracers, structure-affinity relationships and in vitro metabolic stability.
    Grosse Maestrup E, Wiese C, Schepmann D, Hiller A, Fischer S, Scheunemann M, Brust P, Wünsch B.
    Bioorg Med Chem; 2009 May 15; 17(10):3630-41. PubMed ID: 19394833
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  • 26. Synthesis and structure-activity relationship studies for hydantoins and analogues as voltage-gated sodium channel ligands.
    Zha C, Brown GB, Brouillette WJ.
    J Med Chem; 2004 Dec 16; 47(26):6519-28. PubMed ID: 15588087
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  • 28. Exploring the importance of piperazine N-atoms for sigma(2) receptor affinity and activity in a series of analogs of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28).
    Berardi F, Abate C, Ferorelli S, Uricchio V, Colabufo NA, Niso M, Perrone R.
    J Med Chem; 2009 Dec 10; 52(23):7817-28. PubMed ID: 19842660
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  • 30. Synthesis and structure-activity investigation of iodinated arylhydantoins and arylthiohydantoins for development as androgen receptor radioligands.
    Van Dort ME, Jung YW.
    Bioorg Med Chem Lett; 2004 Nov 01; 14(21):5285-8. PubMed ID: 15454212
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  • 37. Thiophene bioisosteres of spirocyclic sigma receptor ligands. 1. N-substituted spiro[piperidine-4,4'-thieno[3,2-c]pyrans].
    Oberdorf C, Schepmann D, Vela JM, Diaz JL, Holenz J, Wünsch B.
    J Med Chem; 2008 Oct 23; 51(20):6531-7. PubMed ID: 18816044
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  • 38. Synthesis and pharmacological evaluation of benzannulated derivatives as potent and selective sigma-1 protein ligands.
    Donnier-Maréchal M, Carato P, Le Broc D, Furman C, Melnyk P.
    Eur J Med Chem; 2015 Mar 06; 92():575-82. PubMed ID: 25602932
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  • 40. Dancing of the second aromatic residue around the 6,8-diazabicyclo[3.2.2]nonane framework: influence on sigma receptor affinity and cytotoxicity.
    Holl R, Schepmann D, Fröhlich R, Grünert R, Bednarski PJ, Wünsch B.
    J Med Chem; 2009 Apr 09; 52(7):2126-37. PubMed ID: 19243173
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