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204 related items for PubMed ID: 16140011
1. Synthesis and pharmacological evaluation of Tic-hydantoin derivatives as selective sigma1 ligands. Part 1. Charton J, Cazenave Gassiot A, Girault-Mizzi S, Debreu-Fontaine MA, Melnyk P, Sergheraert C. Bioorg Med Chem Lett; 2005 Nov 01; 15(21):4833-7. PubMed ID: 16140011 [Abstract] [Full Text] [Related]
2. Synthesis and pharmacological evaluation of Tic-hydantoin derivatives as selective sigma1 ligands. Part 2. Cazenave Gassiot A, Charton J, Girault-Mizzi S, Gilleron P, Debreu-Fontaine MA, Sergheraert C, Melnyk P. Bioorg Med Chem Lett; 2005 Nov 01; 15(21):4828-32. PubMed ID: 16140009 [Abstract] [Full Text] [Related]
3. Sigma-1 ligands: Tic-hydantoin as a key pharmacophore. Toussaint M, Mousset D, Foulon C, Jacquemard U, Vaccher C, Melnyk P. Eur J Med Chem; 2010 Jan 01; 45(1):256-63. PubMed ID: 19875205 [Abstract] [Full Text] [Related]
4. Synthesis and quantitative structure-activity relationships of N-(1-benzylpiperidin-4-yl)phenylacetamides and related analogues as potent and selective sigma1 receptor ligands. Huang Y, Hammond PS, Whirrett BR, Kuhner RJ, Wu L, Childers SR, Mach RH. J Med Chem; 1998 Jun 18; 41(13):2361-70. PubMed ID: 9632369 [Abstract] [Full Text] [Related]
5. Design, synthesis and SAR analysis of novel selective sigma1 ligands (Part 2). Rossi D, Urbano M, Pedrali A, Serra M, Zampieri D, Mamolo MG, Laggner C, Zanette C, Florio C, Schepmann D, Wuensch B, Azzolina O, Collina S. Bioorg Med Chem; 2010 Feb 18; 18(3):1204-12. PubMed ID: 20045339 [Abstract] [Full Text] [Related]
6. Tic hydantoin sigma-1 agonist: pharmacological characterization on cocaine-induced stimulant and appetitive effects. Toussaint M, Delair B, Foulon C, Lempereur N, Vaccher C, Maurice T, Melnyk P. Eur Neuropsychopharmacol; 2009 Jul 18; 19(7):504-15. PubMed ID: 19249191 [Abstract] [Full Text] [Related]
7. N-[omega-(Tetralin-1-yl)alkyl] derivatives of 3,3-dimethylpiperidine are highly potent and selective sigma1 or sigma2 ligands. Berardi F, Santoro S, Perrone R, Tortorella V, Govoni S, Lucchi L. J Med Chem; 1998 Oct 08; 41(21):3940-7. PubMed ID: 9767631 [Abstract] [Full Text] [Related]
8. Synthesis and SAR of novel hydantoin derivatives as selective androgen receptor modulators. Zhang X, Allan GF, Sbriscia T, Linton O, Lundeen SG, Sui Z. Bioorg Med Chem Lett; 2006 Nov 15; 16(22):5763-6. PubMed ID: 16959487 [Abstract] [Full Text] [Related]
9. Synthesis of chiral 1-[omega-(4-chlorophenoxy)alkyl]-4-methylpiperidines and their biological evaluation at sigma1, sigma2, and sterol delta8-delta7 isomerase sites. Berardi F, Loiodice F, Fracchiolla G, Colabufo NA, Perrone R, Tortorella V. J Med Chem; 2003 May 22; 46(11):2117-24. PubMed ID: 12747784 [Abstract] [Full Text] [Related]
10. Substituted benzo[d]oxazol-2(3H)-one derivatives with preference for the sigma1 binding site. Zampieri D, Grazia Mamolo M, Laurini E, Zanette C, Florio C, Collina S, Rossi D, Azzolina O, Vio L. Eur J Med Chem; 2009 Jan 22; 44(1):124-30. PubMed ID: 18440098 [Abstract] [Full Text] [Related]
11. Novel sigma receptor ligands: synthesis and biological profile. Prezzavento O, Campisi A, Ronsisvalle S, Li Volti G, Marrazzo A, Bramanti V, Cannavò G, Vanella L, Cagnotto A, Mennini T, Ientile R, Ronsisvalle G. J Med Chem; 2007 Mar 08; 50(5):951-61. PubMed ID: 17328523 [Abstract] [Full Text] [Related]
12. Medicinal Chemistry of σ1 Receptor Ligands: Pharmacophore Models, Synthesis, Structure Affinity Relationships, and Pharmacological Applications. Weber F, Wünsch B. Handb Exp Pharmacol; 2017 Mar 08; 244():51-79. PubMed ID: 28620761 [Abstract] [Full Text] [Related]
13. Hydantoin-substituted 4,6-dichloroindole-2-carboxylic acids as ligands with high affinity for the glycine binding site of the NMDA receptor. Jansen M, Potschka H, Brandt C, Löscher W, Dannhardt G. J Med Chem; 2003 Jan 02; 46(1):64-73. PubMed ID: 12502360 [Abstract] [Full Text] [Related]
14. Synthesis and receptor binding studies of some new arylcarboxamide derivatives as sigma-1 ligands. Zampieri D, Laurini E, Vio L, Golob S, Fermeglia M, Pricl S, Mamolo MG. Bioorg Med Chem Lett; 2014 Feb 15; 24(4):1021-5. PubMed ID: 24486131 [Abstract] [Full Text] [Related]
15. Synthesis and structure-affinity relationships of novel spirocyclic sigma receptor ligands with furopyrazole structure. Schläger T, Schepmann D, Würthwein EU, Wünsch B. Bioorg Med Chem; 2008 Mar 15; 16(6):2992-3001. PubMed ID: 18221879 [Abstract] [Full Text] [Related]
16. Phenylalkyl 1,2-diamines as sigma-receptor ligands: the discovery of novel antidepressant agents. Kim YG, Seo SY, Heo J, Park CE, Lee EH, Choi YM. Methods Find Exp Clin Pharmacol; 2006 Mar 15; 28(1):7-11. PubMed ID: 16541191 [Abstract] [Full Text] [Related]
18. New synthesis of tic-hydantoins sigma-1 ligands and pharmacological evaluation on cocaine-induced stimulant effects. Toussaint M, Debreu-Fontaine MA, Maurice T, Melnyk P. Med Chem; 2010 Nov 15; 6(6):355-73. PubMed ID: 20843289 [Abstract] [Full Text] [Related]
19. 1'-Benzyl-3,4-dihydrospiro[2H-1- benzothiopyran-2,4'-piperidine] (spipethiane), a potent and highly selective sigma1 ligand. Quaglia W, Giannella M, Piergentili A, Pigini M, Brasili L, Di Toro R, Rossetti L, Spampinato S, Melchiorre C. J Med Chem; 1998 May 07; 41(10):1557-60. PubMed ID: 9572880 [No Abstract] [Full Text] [Related]
20. A medicinal-chemistry-guided approach to selective and druglike sigma 1 ligands. Corbera J, Vaño D, Martínez D, Vela JM, Zamanillo D, Dordal A, Andreu F, Hernandez E, Perez R, Escriche M, Salgado L, Yeste S, Serafini MT, Pascual R, Alegre J, Calvet MC, Cano N, Carro M, Buschmann H, Holenz J. ChemMedChem; 2006 Jan 07; 1(1):140-54. PubMed ID: 16892345 [Abstract] [Full Text] [Related] Page: [Next] [New Search]