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1461 related items for PubMed ID: 16140948

  • 1. Activation of mammalian target of rapamycin in transformed B lymphocytes is nutrient dependent but independent of Akt, mitogen-activated protein kinase/extracellular signal-regulated kinase kinase, insulin growth factor-I, and serum.
    Wlodarski P, Kasprzycka M, Liu X, Marzec M, Robertson ES, Slupianek A, Wasik MA.
    Cancer Res; 2005 Sep 01; 65(17):7800-8. PubMed ID: 16140948
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  • 2. Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway.
    Marzec M, Kasprzycka M, Liu X, El-Salem M, Halasa K, Raghunath PN, Bucki R, Wlodarski P, Wasik MA.
    Oncogene; 2007 Aug 16; 26(38):5606-14. PubMed ID: 17353907
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  • 3. PI3K-FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survival.
    Coutant A, Rescan C, Gilot D, Loyer P, Guguen-Guillouzo C, Baffet G.
    Hepatology; 2002 Nov 16; 36(5):1079-88. PubMed ID: 12395317
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  • 4. A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells.
    Sekulić A, Hudson CC, Homme JL, Yin P, Otterness DM, Karnitz LM, Abraham RT.
    Cancer Res; 2000 Jul 01; 60(13):3504-13. PubMed ID: 10910062
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  • 8. Insulin, insulin-like growth factor-I, and platelet-derived growth factor activate extracellular signal-regulated kinase by distinct pathways in muscle cells.
    Tsakiridis T, Tsiani E, Lekas P, Bergman A, Cherepanov V, Whiteside C, Downey GP.
    Biochem Biophys Res Commun; 2001 Oct 19; 288(1):205-11. PubMed ID: 11594774
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  • 9. LY303511 (2-piperazinyl-8-phenyl-4H-1-benzopyran-4-one) acts via phosphatidylinositol 3-kinase-independent pathways to inhibit cell proliferation via mammalian target of rapamycin (mTOR)- and non-mTOR-dependent mechanisms.
    Kristof AS, Pacheco-Rodriguez G, Schremmer B, Moss J.
    J Pharmacol Exp Ther; 2005 Sep 19; 314(3):1134-43. PubMed ID: 15923340
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  • 10. Inhibition of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway but not the MEK/ERK pathway attenuates laminin-mediated small cell lung cancer cellular survival and resistance to imatinib mesylate or chemotherapy.
    Tsurutani J, West KA, Sayyah J, Gills JJ, Dennis PA.
    Cancer Res; 2005 Sep 15; 65(18):8423-32. PubMed ID: 16166321
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  • 11. Involvement of the Akt/mTOR pathway on EGF-induced cell transformation.
    Nomura M, He Z, Koyama I, Ma WY, Miyamoto K, Dong Z.
    Mol Carcinog; 2003 Sep 15; 38(1):25-32. PubMed ID: 12949840
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  • 12. Antimitogenic and proapoptotic activities of methylseleninic acid in vascular endothelial cells and associated effects on PI3K-AKT, ERK, JNK and p38 MAPK signaling.
    Wang Z, Jiang C, Ganther H, Lü J.
    Cancer Res; 2001 Oct 01; 61(19):7171-8. PubMed ID: 11585751
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  • 13. TOR kinase and Ran are downstream from PI3K/Akt in H2O2-induced mitosis.
    Radisavljevic ZM, González-Flecha B.
    J Cell Biochem; 2004 Apr 15; 91(6):1293-300. PubMed ID: 15048882
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  • 14. Signal transduction pathways in androgen-dependent and -independent prostate cancer cell proliferation.
    Ghosh PM, Malik SN, Bedolla RG, Wang Y, Mikhailova M, Prihoda TJ, Troyer DA, Kreisberg JI.
    Endocr Relat Cancer; 2005 Mar 15; 12(1):119-34. PubMed ID: 15788644
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  • 15. Inhibition of mTOR activity restores tamoxifen response in breast cancer cells with aberrant Akt Activity.
    deGraffenried LA, Friedrichs WE, Russell DH, Donzis EJ, Middleton AK, Silva JM, Roth RA, Hidalgo M.
    Clin Cancer Res; 2004 Dec 01; 10(23):8059-67. PubMed ID: 15585641
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  • 17. The phosphatidylinositol 3-kinase/AKT kinase pathway in multiple myeloma plasma cells: roles in cytokine-dependent survival and proliferative responses.
    Tu Y, Gardner A, Lichtenstein A.
    Cancer Res; 2000 Dec 01; 60(23):6763-70. PubMed ID: 11118064
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  • 18. Activation of phosphatidylinositol 3-kinase, Akt, and mammalian target of rapamycin is necessary for hypoxia-induced pulmonary artery adventitial fibroblast proliferation.
    Gerasimovskaya EV, Tucker DA, Stenmark KR.
    J Appl Physiol (1985); 2005 Feb 01; 98(2):722-31. PubMed ID: 15501927
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  • 19. Epstein-Barr virus (EBV) LMP2A mediates B-lymphocyte survival through constitutive activation of the Ras/PI3K/Akt pathway.
    Portis T, Longnecker R.
    Oncogene; 2004 Nov 11; 23(53):8619-28. PubMed ID: 15361852
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  • 20. Activation of RAF/MEK/ERK and PI3K/AKT/mTOR pathways in pituitary adenomas and their effects on downstream effectors.
    Dworakowska D, Wlodek E, Leontiou CA, Igreja S, Cakir M, Teng M, Prodromou N, Góth MI, Grozinsky-Glasberg S, Gueorguiev M, Kola B, Korbonits M, Grossman AB.
    Endocr Relat Cancer; 2009 Dec 11; 16(4):1329-38. PubMed ID: 19620247
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