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636 related items for PubMed ID: 16140955

  • 1. Benzodithiophenes potentiate differentiation of acute promyelocytic leukemia cells by lowering the threshold for ligand-mediated corepressor/coactivator exchange with retinoic acid receptor alpha and enhancing changes in all-trans-retinoic acid-regulated gene expression.
    Xu K, Guidez F, Glasow A, Chung D, Petrie K, Stegmaier K, Wang KK, Zhang J, Jing Y, Zelent A, Waxman S.
    Cancer Res; 2005 Sep 01; 65(17):7856-65. PubMed ID: 16140955
    [Abstract] [Full Text] [Related]

  • 2. Reduced retinoic acid-sensitivities of nuclear receptor corepressor binding to PML- and PLZF-RARalpha underlie molecular pathogenesis and treatment of acute promyelocytic leukemia.
    Guidez F, Ivins S, Zhu J, Söderström M, Waxman S, Zelent A.
    Blood; 1998 Apr 15; 91(8):2634-42. PubMed ID: 9531570
    [Abstract] [Full Text] [Related]

  • 3. Common defects of different retinoic acid resistant promyelocytic leukemia cells are persistent telomerase activity and nuclear body disorganization.
    Nason-Burchenal K, Maerz W, Albanell J, Allopenna J, Martin P, Moore MA, Dmitrovsky E.
    Differentiation; 1997 Aug 15; 61(5):321-31. PubMed ID: 9342843
    [Abstract] [Full Text] [Related]

  • 4. Benzodithiophenes induce differentiation and apoptosis in human leukemia cells.
    Jing Y, Hellinger N, Xia L, Monks A, Sausville EA, Zelent A, Waxman S.
    Cancer Res; 2005 Sep 01; 65(17):7847-55. PubMed ID: 16140954
    [Abstract] [Full Text] [Related]

  • 5. PML/RARα-Regulated miR-181a/b Cluster Targets the Tumor Suppressor RASSF1A in Acute Promyelocytic Leukemia.
    Bräuer-Hartmann D, Hartmann JU, Wurm AA, Gerloff D, Katzerke C, Verga Falzacappa MV, Pelicci PG, Müller-Tidow C, Tenen DG, Niederwieser D, Behre G.
    Cancer Res; 2015 Aug 15; 75(16):3411-24. PubMed ID: 26041820
    [Abstract] [Full Text] [Related]

  • 6. Mechanisms of all-trans retinoic acid-induced differentiation of acute promyelocytic leukemia cells.
    Zhang JW, Wang JY, Chen SJ, Chen Z.
    J Biosci; 2000 Sep 15; 25(3):275-84. PubMed ID: 11022230
    [Abstract] [Full Text] [Related]

  • 7. The transcriptional corepressor CBFA2T3 inhibits all-trans-retinoic acid-induced myeloid gene expression and differentiation in acute myeloid leukemia.
    Steinauer N, Guo C, Zhang J.
    J Biol Chem; 2020 Jul 03; 295(27):8887-8900. PubMed ID: 32434928
    [Abstract] [Full Text] [Related]

  • 8. All-trans retinoic acid (ATRA)-induced TFEB expression is required for myeloid differentiation in acute promyelocytic leukemia (APL).
    Orfali N, O'Donovan TR, Cahill MR, Benjamin D, Nanus DM, McKenna SL, Gudas LJ, Mongan NP.
    Eur J Haematol; 2020 Mar 03; 104(3):236-250. PubMed ID: 31811682
    [Abstract] [Full Text] [Related]

  • 9. Granulocytic differentiation of human NB4 promyelocytic leukemia cells induced by all-trans retinoic acid metabolites.
    Idres N, Benoît G, Flexor MA, Lanotte M, Chabot GG.
    Cancer Res; 2001 Jan 15; 61(2):700-5. PubMed ID: 11212271
    [Abstract] [Full Text] [Related]

  • 10. Designed ATRA analogue active against ATRA-resistant acute promyelocytic leukemia cells having a single nucleotide substitution in their retinoic acid receptor.
    Komura N, Ikeda Y, Masuda N, Umezawa Y, Ito K, Kizaki M, Umezawa K.
    Leuk Res; 2007 Mar 15; 31(3):301-13. PubMed ID: 16968653
    [Abstract] [Full Text] [Related]

  • 11. Interactions of STAT5b-RARalpha, a novel acute promyelocytic leukemia fusion protein, with retinoic acid receptor and STAT3 signaling pathways.
    Dong S, Tweardy DJ.
    Blood; 2002 Apr 15; 99(8):2637-46. PubMed ID: 11929748
    [Abstract] [Full Text] [Related]

  • 12. Growth suppression of acute promyelocytic leukemia cells having increased expression of the non-rearranged alleles: RAR alpha or PML.
    Ahn MJ, Nason-Burchenal K, Moasser MM, Dmitrovsky E.
    Oncogene; 1995 Jun 15; 10(12):2307-14. PubMed ID: 7784078
    [Abstract] [Full Text] [Related]

  • 13. Triterpenoid CDDO-Im downregulates PML/RARalpha expression in acute promyelocytic leukemia cells.
    Ikeda T, Kimura F, Nakata Y, Sato K, Ogura K, Motoyoshi K, Sporn M, Kufe D.
    Cell Death Differ; 2005 May 15; 12(5):523-31. PubMed ID: 15746941
    [Abstract] [Full Text] [Related]

  • 14. [Basic and clinical studies of the gene product-targeting therapy based on leukemogenesis--editorial].
    Chen SJ, Chen LJ, Zhou GB.
    Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2005 Feb 15; 13(1):1-8. PubMed ID: 15748426
    [Abstract] [Full Text] [Related]

  • 15. Activation of G0S2 is coordinated by recruitment of PML/RARα and C/EBPε to its promoter during ATRA-induced APL differentiation.
    Zhang F, Zhu YL, Deng WL, Zhu J, Zhang J.
    J Leukoc Biol; 2017 Mar 15; 101(3):655-664. PubMed ID: 27605212
    [Abstract] [Full Text] [Related]

  • 16. Mutations in the E-domain of RAR portion of the PML/RAR chimeric gene may confer clinical resistance to all-trans retinoic acid in acute promyelocytic leukemia.
    Imaizumi M, Suzuki H, Yoshinari M, Sato A, Saito T, Sugawara A, Tsuchiya S, Hatae Y, Fujimoto T, Kakizuka A, Konno T, Iinuma K.
    Blood; 1998 Jul 15; 92(2):374-82. PubMed ID: 9657734
    [Abstract] [Full Text] [Related]

  • 17. C-fms expression correlates with monocytic differentiation in PML-RAR alpha+ acute promyelocytic leukemia.
    Riccioni R, Saulle E, Militi S, Sposi NM, Gualtiero M, Mauro N, Mancini M, Diverio D, Lo Coco F, Peschle C, Testa U.
    Leukemia; 2003 Jan 15; 17(1):98-113. PubMed ID: 12529666
    [Abstract] [Full Text] [Related]

  • 18. Accelerated degradation of PML-retinoic acid receptor alpha (PML-RARA) oncoprotein by all-trans-retinoic acid in acute promyelocytic leukemia: possible role of the proteasome pathway.
    Yoshida H, Kitamura K, Tanaka K, Omura S, Miyazaki T, Hachiya T, Ohno R, Naoe T.
    Cancer Res; 1996 Jul 01; 56(13):2945-8. PubMed ID: 8674046
    [Abstract] [Full Text] [Related]

  • 19. Tyrosine kinase inhibitor STI571 potentiates the pharmacologic activity of retinoic acid in acute promyelocytic leukemia cells: effects on the degradation of RARalpha and PML-RARalpha.
    Gianni' M, Kalaç Y, Ponzanelli I, Rambaldi A, Terao M, Garattini E.
    Blood; 2001 May 15; 97(10):3234-43. PubMed ID: 11342454
    [Abstract] [Full Text] [Related]

  • 20. CCAAT/enhancer binding protein epsilon is a potential retinoid target gene in acute promyelocytic leukemia treatment.
    Park DJ, Chumakov AM, Vuong PT, Chih DY, Gombart AF, Miller WH, Koeffler HP.
    J Clin Invest; 1999 May 15; 103(10):1399-408. PubMed ID: 10330422
    [Abstract] [Full Text] [Related]

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