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Journal Abstract Search

952 related items for PubMed ID: 16142720

  • 1. Preclinical pharmacokinetics of a novel HIV-1 attachment inhibitor BMS-378806 and prediction of its human pharmacokinetics.
    Yang Z, Zadjura L, D'Arienzo C, Marino A, Santone K, Klunk L, Greene D, Lin PF, Colonno R, Wang T, Meanwell N, Hansel S.
    Biopharm Drug Dispos; 2005 Dec; 26(9):387-402. PubMed ID: 16142720
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  • 2. Preclinical pharmacokinetics and metabolism of 6-(4-(2,5-difluorophenyl)oxazol-5-yl)-3-isopropyl-[1,2,4]-triazolo[4,3-a]pyridine, a novel and selective p38alpha inhibitor: identification of an active metabolite in preclinical species and human liver microsomes.
    Kalgutkar AS, Hatch HL, Kosea F, Nguyen HT, Choo EF, McClure KF, Taylor TJ, Henne KR, Kuperman AV, Dombroski MA, Letavic MA.
    Biopharm Drug Dispos; 2006 Nov; 27(8):371-86. PubMed ID: 16944451
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  • 3. Pharmacokinetics, disposition and lipid-modulating activity of 5-{2-[4-(3,4-difluorophenoxy)-phenyl]-ethylsulfamoyl}-2-methyl-benzoic acid, a potent and subtype-selective peroxisome proliferator-activated receptor alpha agonist in preclinical species and human.
    Frederick KS, Maurer TS, Kalgutkar AS, Royer LJ, Francone OL, Winter SM, Terra SG, Chen D, Gao X.
    Xenobiotica; 2009 Oct; 39(10):766-81. PubMed ID: 19622022
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  • 4. P-glycoprotein plays a role in the oral absorption of BMS-387032, a potent cyclin-dependent kinase 2 inhibitor, in rats.
    Kamath AV, Chong S, Chang M, Marathe PH.
    Cancer Chemother Pharmacol; 2005 Feb; 55(2):110-6. PubMed ID: 15338193
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  • 11. Pharmacokinetics of the dipeptidyl peptidase 4 inhibitor saxagliptin in rats, dogs, and monkeys and clinical projections.
    Fura A, Khanna A, Vyas V, Koplowitz B, Chang SY, Caporuscio C, Boulton DW, Christopher LJ, Chadwick KD, Hamann LG, Humphreys WG, Kirby M.
    Drug Metab Dispos; 2009 Jun; 37(6):1164-71. PubMed ID: 19251818
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  • 13. Orally active inhibitors of human leukocyte elastase. II. Disposition of L-694,458 in rats and rhesus monkeys.
    Vincent SH, Painter SK, Luffer-Atlas D, Karanam BV, McGowan E, Cioffe C, Doss G, Chiu SH.
    Drug Metab Dispos; 1997 Aug; 25(8):932-9. PubMed ID: 9280401
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  • 14. Pharmacokinetic characterization of a natural product-inspired novel MEK1 inhibitor E6201 in preclinical species.
    Kumar V, Schuck EL, Pelletier RD, Farah N, Condon KB, Ye M, Rowbottom C, King BM, Zhang ZY, Saxton PL, Wong YN.
    Cancer Chemother Pharmacol; 2012 Jan; 69(1):229-37. PubMed ID: 21698359
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  • 16. Toxicokinetics of 2',3'-didehydro-3'-deoxythymidine, stavudine (D4T).
    Kaul S, Dandekar KA, Schilling BE, Barbhaiya RH.
    Drug Metab Dispos; 1999 Jan; 27(1):1-12. PubMed ID: 9884303
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  • 18. Route-dependent nonlinear pharmacokinetics of a novel HIV protease inhibitor: involvement of enzyme inactivation.
    Lin JH, Chen IW, Chiba M, Nishime JA, Deluna FA.
    Drug Metab Dispos; 2000 Apr; 28(4):460-6. PubMed ID: 10725315
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