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Journal Abstract Search

102 related items for PubMed ID: 16142924

  • 1. Purification and functional reconstitution of the rat organic cation transporter OCT1.
    Keller T, Elfeber M, Gorboulev V, Reiländer H, Koepsell H.
    Biochemistry; 2005 Sep 13; 44(36):12253-63. PubMed ID: 16142924
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  • 2. Subtype-specific affinity for corticosterone of rat organic cation transporters rOCT1 and rOCT2 depends on three amino acids within the substrate binding region.
    Gorboulev V, Shatskaya N, Volk C, Koepsell H.
    Mol Pharmacol; 2005 May 13; 67(5):1612-9. PubMed ID: 15662045
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  • 6. High-affinity cation binding to organic cation transporter 1 induces movement of helix 11 and blocks transport after mutations in a modeled interaction domain between two helices.
    Gorbunov D, Gorboulev V, Shatskaya N, Mueller T, Bamberg E, Friedrich T, Koepsell H.
    Mol Pharmacol; 2008 Jan 13; 73(1):50-61. PubMed ID: 17940192
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  • 8. Assay Conditions Influence Affinities of Rat Organic Cation Transporter 1: Analysis of Mutagenesis in the Modeled Outward-Facing Cleft by Measuring Effects of Substrates and Inhibitors on Initial Uptake.
    Gorboulev V, Rehman S, Albert CM, Roth U, Meyer MJ, Tzvetkov MV, Mueller TD, Koepsell H.
    Mol Pharmacol; 2018 Apr 13; 93(4):402-415. PubMed ID: 29339398
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  • 11. The large extracellular loop of organic cation transporter 1 influences substrate affinity and is pivotal for oligomerization.
    Keller T, Egenberger B, Gorboulev V, Bernhard F, Uzelac Z, Gorbunov D, Wirth C, Koppatz S, Dötsch V, Hunte C, Sitte HH, Koepsell H.
    J Biol Chem; 2011 Oct 28; 286(43):37874-86. PubMed ID: 21896487
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  • 12. Choline transport via choline transporter-like protein 1 in conditionally immortalized rat syncytiotrophoblast cell lines TR-TBT.
    Lee NY, Choi HM, Kang YS.
    Placenta; 2009 Apr 28; 30(4):368-74. PubMed ID: 19246089
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  • 15. Electrogenic properties and substrate specificity of the polyspecific rat cation transporter rOCT1.
    Busch AE, Quester S, Ulzheimer JC, Waldegger S, Gorboulev V, Arndt P, Lang F, Koepsell H.
    J Biol Chem; 1996 Dec 20; 271(51):32599-604. PubMed ID: 8955087
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  • 16. Comparison of the kinetic characteristics of inhibitory effects exerted by biguanides and H2-blockers on human and rat organic cation transporter-mediated transport: Insight into the development of drug candidates.
    Umehara KI, Iwatsubo T, Noguchi K, Kamimura H.
    Xenobiotica; 2007 Jun 20; 37(6):618-34. PubMed ID: 17614008
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  • 17. Individual PKC-phosphorylation sites in organic cation transporter 1 determine substrate selectivity and transport regulation.
    Ciarimboli G, Koepsell H, Iordanova M, Gorboulev V, Dürner B, Lang D, Edemir B, Schröter R, Van Le T, Schlatter E.
    J Am Soc Nephrol; 2005 Jun 20; 16(6):1562-70. PubMed ID: 15829703
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  • 18. Identification of human metabolites of (-)-N-{2-[(R)-3-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a novel If channel inhibitor, and investigation of the transporter-mediated renal and hepatic excretion of these metabolites.
    Umehara K, Shirai N, Iwatsubo T, Noguchi K, Usui T, Kamimura H.
    Drug Metab Dispos; 2009 Aug 20; 37(8):1646-57. PubMed ID: 19439489
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  • 19. Transport of the dopamine D2 agonist pramipexole by rat organic cation transporters OCT1 and OCT2 in kidney.
    Ishiguro N, Saito A, Yokoyama K, Morikawa M, Igarashi T, Tamai I.
    Drug Metab Dispos; 2005 Apr 20; 33(4):495-9. PubMed ID: 15640376
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