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Journal Abstract Search


153 related items for PubMed ID: 16148009

  • 1. Ablation of the otcC gene encoding a post-polyketide hydroxylase from the oxytetracyline biosynthetic pathway in Streptomyces rimosus results in novel polyketides with altered chain length.
    Peric-Concha N, Borovicka B, Long PF, Hranueli D, Waterman PG, Hunter IS.
    J Biol Chem; 2005 Nov 11; 280(45):37455-60. PubMed ID: 16148009
    [Abstract] [Full Text] [Related]

  • 2. Disruption of an aromatase/cyclase from the oxytetracycline gene cluster of Streptomyces rimosus results in production of novel polyketides with shorter chain lengths.
    Petkovic H, Thamchaipenet A, Zhou LH, Hranueli D, Raspor P, Waterman PG, Hunter IS.
    J Biol Chem; 1999 Nov 12; 274(46):32829-34. PubMed ID: 10551844
    [Abstract] [Full Text] [Related]

  • 3. Phosphate control of oxytetracycline production by Streptomyces rimosus is at the level of transcription from promoters overlapped by tandem repeats similar to those of the DNA-binding sites of the OmpR family.
    McDowall KJ, Thamchaipenet A, Hunter IS.
    J Bacteriol; 1999 May 12; 181(10):3025-32. PubMed ID: 10322002
    [Abstract] [Full Text] [Related]

  • 4. Sequences of the oxytetracycline polyketide synthase-encoding otc genes from Streptomyces rimosus.
    Kim ES, Bibb MJ, Butler MJ, Hopwood DA, Sherman DH.
    Gene; 1994 Apr 08; 141(1):141-2. PubMed ID: 8163168
    [Abstract] [Full Text] [Related]

  • 5. Oxytetracycline biosynthesis improvement in Streptomyces rimosus following duplication of minimal PKS genes.
    Yu L, Cao N, Wang L, Xiao C, Guo M, Chu J, Zhuang Y, Zhang S.
    Enzyme Microb Technol; 2012 May 10; 50(6-7):318-24. PubMed ID: 22500899
    [Abstract] [Full Text] [Related]

  • 6. Identification of OxyE as an ancillary oxygenase during tetracycline biosynthesis.
    Wang P, Zhang W, Zhan J, Tang Y.
    Chembiochem; 2009 Jun 15; 10(9):1544-50. PubMed ID: 19472250
    [Abstract] [Full Text] [Related]

  • 7. Heterologous biosynthesis of amidated polyketides with novel cyclization regioselectivity from oxytetracycline polyketide synthase.
    Zhang W, Watanabe K, Wang CC, Tang Y.
    J Nat Prod; 2006 Nov 15; 69(11):1633-6. PubMed ID: 17125237
    [Abstract] [Full Text] [Related]

  • 8. Cloning and heterologous expression in Streptomyces lividans of Streptomyces rimosus genes involved in oxytetracycline biosynthesis.
    Binnie C, Warren M, Butler MJ.
    J Bacteriol; 1989 Feb 15; 171(2):887-95. PubMed ID: 2914874
    [Abstract] [Full Text] [Related]

  • 9. Genetic characterization of enzymes involved in the priming steps of oxytetracycline biosynthesis in Streptomyces rimosus.
    Wang P, Gao X, Chooi YH, Deng Z, Tang Y.
    Microbiology (Reading); 2011 Aug 15; 157(Pt 8):2401-2409. PubMed ID: 21622525
    [Abstract] [Full Text] [Related]

  • 10. Oxytetracycline hyper-production through targeted genome reduction of Streptomyces rimosus.
    Pšeničnik A, Slemc L, Avbelj M, Tome M, Šala M, Herron P, Shmatkov M, Petek M, Baebler Š, Mrak P, Hranueli D, Starčević A, Hunter IS, Petković H.
    mSystems; 2024 May 16; 9(5):e0025024. PubMed ID: 38564716
    [Abstract] [Full Text] [Related]

  • 11. Solution structure and dynamics of oxytetracycline polyketide synthase acyl carrier protein from Streptomyces rimosus.
    Findlow SC, Winsor C, Simpson TJ, Crosby J, Crump MP.
    Biochemistry; 2003 Jul 22; 42(28):8423-33. PubMed ID: 12859187
    [Abstract] [Full Text] [Related]

  • 12. Identification of a cluster-situated activator of oxytetracycline biosynthesis and manipulation of its expression for improved oxytetracycline production in Streptomyces rimosus.
    Yin S, Wang W, Wang X, Zhu Y, Jia X, Li S, Yuan F, Zhang Y, Yang K.
    Microb Cell Fact; 2015 Apr 02; 14():46. PubMed ID: 25886456
    [Abstract] [Full Text] [Related]

  • 13. Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase.
    Zhang W, Ames BD, Tsai SC, Tang Y.
    Appl Environ Microbiol; 2006 Apr 02; 72(4):2573-80. PubMed ID: 16597959
    [Abstract] [Full Text] [Related]

  • 14. Polyketide chain length control by chain length factor.
    Tang Y, Tsai SC, Khosla C.
    J Am Chem Soc; 2003 Oct 22; 125(42):12708-9. PubMed ID: 14558809
    [Abstract] [Full Text] [Related]

  • 15. [Polyketide antibiotics produced by polyketide synthase in streptomyces--a review].
    Chen M, Wang G, Dai S, Xie L, Li X.
    Wei Sheng Wu Xue Bao; 2009 Dec 22; 49(12):1555-63. PubMed ID: 20222438
    [Abstract] [Full Text] [Related]

  • 16. A hydroxylase-like gene product contributes to synthesis of a polyketide spore pigment in Streptomyces halstedii.
    Blanco G, Pereda A, Brian P, Méndez C, Chater KF, Salas JA.
    J Bacteriol; 1993 Dec 22; 175(24):8043-8. PubMed ID: 8253693
    [Abstract] [Full Text] [Related]

  • 17. The role of erythromycin C-12 hydroxylase, EryK, as a substitute for PikC hydroxylase in pikromycin biosynthesis.
    Lee SK, Basnet DB, Choi CY, Sohng JK, Ahn JS, Yoon YJ.
    Bioorg Chem; 2004 Dec 22; 32(6):549-59. PubMed ID: 15530995
    [Abstract] [Full Text] [Related]

  • 18. Heterologous expression of the naphthocyclinone hydroxylase gene from Streptomyces arenae for production of novel hybrid polyketides.
    Brünke P, Sterner O, Bailey JE, Minas W.
    Antonie Van Leeuwenhoek; 2001 Sep 22; 79(3-4):235-45. PubMed ID: 11816965
    [Abstract] [Full Text] [Related]

  • 19. Comparative characterization of the lactimidomycin and iso-migrastatin biosynthetic machineries revealing unusual features for acyltransferase-less type I polyketide synthases and providing an opportunity to engineer new analogues.
    Seo JW, Ma M, Kwong T, Ju J, Lim SK, Jiang H, Lohman JR, Yang C, Cleveland J, Zazopoulos E, Farnet CM, Shen B.
    Biochemistry; 2014 Dec 16; 53(49):7854-65. PubMed ID: 25405956
    [Abstract] [Full Text] [Related]

  • 20. Cloning, sequencing and analysis of the enterocin biosynthesis gene cluster from the marine isolate 'Streptomyces maritimus': evidence for the derailment of an aromatic polyketide synthase.
    Piel J, Hertweck C, Shipley PR, Hunt DM, Newman MS, Moore BS.
    Chem Biol; 2000 Dec 16; 7(12):943-55. PubMed ID: 11137817
    [Abstract] [Full Text] [Related]


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