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Journal Abstract Search

288 related items for PubMed ID: 16159025

  • 1. Targeting glucokinase activation for the treatment of type 2 diabetes--a status review.
    Sarabu R, Grimsby J.
    Curr Opin Drug Discov Devel; 2005 Sep; 8(5):631-7. PubMed ID: 16159025
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  • 2. Novel glucokinase activators: a patent review (2008 - 2010).
    Sarabu R, Berthel SJ, Kester RF, Tilley JW.
    Expert Opin Ther Pat; 2011 Jan; 21(1):13-33. PubMed ID: 21155690
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  • 3. Small molecule glucokinase activators as novel anti-diabetic agents.
    Leighton B, Atkinson A, Coghlan MP.
    Biochem Soc Trans; 2005 Apr; 33(Pt 2):371-4. PubMed ID: 15787609
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  • 4. A patent review of glucokinase activators and disruptors of the glucokinase--glucokinase regulatory protein interaction: 2011-2014.
    Filipski KJ, Pfefferkorn JA.
    Expert Opin Ther Pat; 2014 Aug; 24(8):875-91. PubMed ID: 24821087
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  • 5. Research and development of glucokinase activators for diabetes therapy: theoretical and practical aspects.
    Matschinsky FM, Zelent B, Doliba NM, Kaestner KH, Vanderkooi JM, Grimsby J, Berthel SJ, Sarabu R.
    Handb Exp Pharmacol; 2011 Aug; (203):357-401. PubMed ID: 21484579
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  • 7. Design, synthesis and SAR of novel glucokinase activators.
    Cheruvallath ZS, Gwaltney SL, Sabat M, Tang M, Feng J, Wang H, Miura J, Guntupalli P, Jennings A, Hosfield D, Lee B, Wu Y.
    Bioorg Med Chem Lett; 2013 Apr 01; 23(7):2166-71. PubMed ID: 23434031
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  • 8. A report of 2 new cases of MODY2 and review of the literature: implications in the search for type 2 diabetes drugs.
    Shammas C, Neocleous V, Phelan MM, Lian LY, Skordis N, Phylactou LA.
    Metabolism; 2013 Nov 01; 62(11):1535-42. PubMed ID: 23890519
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  • 9. Novel, highly potent systemic glucokinase activators for the treatment of Type 2 Diabetes Mellitus.
    Xu J, Lin S, Myers RW, Addona G, Berger JP, Campbell B, Chen HS, Chen Z, Eiermann GJ, Elowe NH, Farrer BT, Feng W, Fu Q, Kats-Kagan R, Kavana M, Malkani S, McMasters DR, Mitra K, Pachanski MJ, Tong X, Trujillo ME, Xu L, Zhang B, Zhang F, Zhang R, Parmee ER.
    Bioorg Med Chem Lett; 2017 May 01; 27(9):2069-2073. PubMed ID: 28284804
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  • 13. Discovery of orally active hepatoselective glucokinase activators for treatment of Type II Diabetes Mellitus.
    Xu J, Lin S, Myers RW, Trujillo ME, Pachanski MJ, Malkani S, Chen HS, Chen Z, Campbell B, Eiermann GJ, Elowe N, Farrer BT, Feng W, Fu Q, Kats-Kagan R, Kavana M, McMasters DR, Mitra K, Tong X, Xu L, Zhang F, Zhang R, Addona GH, Berger JP, Zhang B, Parmee ER.
    Bioorg Med Chem Lett; 2017 May 01; 27(9):2063-2068. PubMed ID: 28284809
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  • 16. Glucokinase and glucose homeostasis: proven concepts and new ideas.
    Zelent D, Najafi H, Odili S, Buettger C, Weik-Collins H, Li C, Doliba N, Grimsby J, Matschinsky FM.
    Biochem Soc Trans; 2005 Feb 01; 33(Pt 1):306-10. PubMed ID: 15667334
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  • 18. Recent clinical advances of glucokinase activators in the treatment of diabetes mellitus type 2.
    Li W, Zhang X, Sun Y, Liu Z.
    Pharmazie; 2020 Jun 01; 75(6):230-235. PubMed ID: 32539915
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  • 19. Discovery of a potent glucokinase activator with a favorable liver and pancreas distribution pattern for the treatment of type 2 diabetes mellitus.
    Fujieda H, Kogami M, Sakairi M, Kato N, Makino M, Takahashi N, Miyazawa T, Harada S, Yamashita T.
    Eur J Med Chem; 2018 Aug 05; 156():269-294. PubMed ID: 30006171
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  • 20. Glucokinase activators in diabetes management.
    Coghlan M, Leighton B.
    Expert Opin Investig Drugs; 2008 Feb 05; 17(2):145-67. PubMed ID: 18230050
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