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269 related items for PubMed ID: 16159882

  • 1. A role for the distal carboxyl tails in generating the novel pharmacology and G protein activation profile of mu and delta opioid receptor hetero-oligomers.
    Fan T, Varghese G, Nguyen T, Tse R, O'Dowd BF, George SR.
    J Biol Chem; 2005 Nov 18; 280(46):38478-88. PubMed ID: 16159882
    [Abstract] [Full Text] [Related]

  • 2. Selective interference of beta-arrestin 1 with kappa and delta but not mu opioid receptor/G protein coupling.
    Cheng ZJ, Yu QM, Wu YL, Ma L, Pei G.
    J Biol Chem; 1998 Sep 18; 273(38):24328-33. PubMed ID: 9733719
    [Abstract] [Full Text] [Related]

  • 3. Oligomerization of mu- and delta-opioid receptors. Generation of novel functional properties.
    George SR, Fan T, Xie Z, Tse R, Tam V, Varghese G, O'Dowd BF.
    J Biol Chem; 2000 Aug 25; 275(34):26128-35. PubMed ID: 10842167
    [Abstract] [Full Text] [Related]

  • 4. Endogenous RGS protein action modulates mu-opioid signaling through Galphao. Effects on adenylyl cyclase, extracellular signal-regulated kinases, and intracellular calcium pathways.
    Clark MJ, Harrison C, Zhong H, Neubig RR, Traynor JR.
    J Biol Chem; 2003 Mar 14; 278(11):9418-25. PubMed ID: 12524446
    [Abstract] [Full Text] [Related]

  • 5. Hetero-oligomers of alpha2A-adrenergic and mu-opioid receptors do not lead to transactivation of G-proteins or altered endocytosis profiles.
    Zhang YQ, Limbird LE.
    Biochem Soc Trans; 2004 Nov 14; 32(Pt 5):856-60. PubMed ID: 15494033
    [Abstract] [Full Text] [Related]

  • 6. Mu and Delta opioid receptors activate the same G proteins in human neuroblastoma SH-SY5Y cells.
    Alt A, Clark MJ, Woods JH, Traynor JR.
    Br J Pharmacol; 2002 Jan 14; 135(1):217-25. PubMed ID: 11786497
    [Abstract] [Full Text] [Related]

  • 7. Selective interactions of mu-opioid receptors with pertussis toxin-sensitive G proteins: involvement of the third intracellular loop and the c-terminal tail in coupling.
    Georgoussi Z, Merkouris M, Mullaney I, Megaritis G, Carr C, Zioudrou C, Milligan G.
    Biochim Biophys Acta; 1997 Dec 12; 1359(3):263-74. PubMed ID: 9434132
    [Abstract] [Full Text] [Related]

  • 8. The bovine mu-opioid receptor: cloning of cDNA and pharmacological characterization of the receptor expressed in mammalian cells.
    Onoprishvili I, Andria ML, Vilim FS, Hiller JM, Simon EJ.
    Brain Res Mol Brain Res; 1999 Nov 10; 73(1-2):129-37. PubMed ID: 10581406
    [Abstract] [Full Text] [Related]

  • 9. Mu-delta opioid receptor functional interaction: Insight using receptor-G protein fusions.
    Snook LA, Milligan G, Kieffer BL, Massotte D.
    J Pharmacol Exp Ther; 2006 Aug 10; 318(2):683-90. PubMed ID: 16690720
    [Abstract] [Full Text] [Related]

  • 10. Activation of type II adenylyl cyclase by the cloned mu-opioid receptor: coupling to multiple G proteins.
    Chan JS, Chiu TT, Wong YH.
    J Neurochem; 1995 Dec 10; 65(6):2682-9. PubMed ID: 7595566
    [Abstract] [Full Text] [Related]

  • 11. Region-dependent G-protein activation by mu-, delta 1- and delta 2-opioid receptor agonists in the brain: comparison between the midbrain and forebrain.
    Tsuji M, Narita M, Mizoguchi H, Narita M, Ohsawa M, Kamei J, Nagase H, Takeda H, Matsumiya T, Tseng LF.
    Life Sci; 1999 Dec 10; 65(16):PL233-9. PubMed ID: 10573190
    [Abstract] [Full Text] [Related]

  • 12. Opioid and cannabinoid receptors share a common pool of GTP-binding proteins in cotransfected cells, but not in cells which endogenously coexpress the receptors.
    Shapira M, Vogel Z, Sarne Y.
    Cell Mol Neurobiol; 2000 Jun 10; 20(3):291-304. PubMed ID: 10789829
    [Abstract] [Full Text] [Related]

  • 13. SoRI 9409, a non-peptide opioid mu receptor agonist/delta receptor antagonist, fails to stimulate [35S]-GTP-gamma-S binding at cloned opioid receptors.
    Xu H, Lu YF, Rice KC, Ananthan S, Rothman RB.
    Brain Res Bull; 2001 Jul 01; 55(4):507-11. PubMed ID: 11543951
    [Abstract] [Full Text] [Related]

  • 14. Differential desensitization of mu- and delta- opioid receptors in selected neural pathways following chronic morphine treatment.
    Noble F, Cox BM.
    Br J Pharmacol; 1996 Jan 01; 117(1):161-9. PubMed ID: 8825358
    [Abstract] [Full Text] [Related]

  • 15. Endogenous regulator of g protein signaling proteins reduce {mu}-opioid receptor desensitization and down-regulation and adenylyl cyclase tolerance in C6 cells.
    Clark MJ, Traynor JR.
    J Pharmacol Exp Ther; 2005 Feb 01; 312(2):809-15. PubMed ID: 15383633
    [Abstract] [Full Text] [Related]

  • 16. Nucleoside diphosphate kinase associated with membranes modulates mu-opioid receptor-mediated [35S]GTPgammaS binding and agonist binding to mu-opioid receptor.
    Zhang D, Li JG, Chen C, Liu-Chen LY.
    Eur J Pharmacol; 1999 Jul 21; 377(2-3):223-31. PubMed ID: 10456435
    [Abstract] [Full Text] [Related]

  • 17. Standard opioid agonists activate heteromeric opioid receptors: evidence for morphine and [d-Ala(2)-MePhe(4)-Glyol(5)]enkephalin as selective μ-δ agonists.
    Yekkirala AS, Kalyuzhny AE, Portoghese PS.
    ACS Chem Neurosci; 2010 Feb 17; 1(2):146-54. PubMed ID: 22816017
    [Abstract] [Full Text] [Related]

  • 18. Chronic exposure to mu-opioid agonists produces constitutive activation of mu-opioid receptors in direct proportion to the efficacy of the agonist used for pretreatment.
    Liu JG, Prather PL.
    Mol Pharmacol; 2001 Jul 17; 60(1):53-62. PubMed ID: 11408600
    [Abstract] [Full Text] [Related]

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