These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

440 related items for PubMed ID: 16168377

  • 1. Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase.
    Song BL, Sever N, DeBose-Boyd RA.
    Mol Cell; 2005 Sep 16; 19(6):829-40. PubMed ID: 16168377
    [Abstract] [Full Text] [Related]

  • 2. Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8.
    Jo Y, Lee PC, Sguigna PV, DeBose-Boyd RA.
    Proc Natl Acad Sci U S A; 2011 Dec 20; 108(51):20503-8. PubMed ID: 22143767
    [Abstract] [Full Text] [Related]

  • 3. Ring finger protein 145 (RNF145) is a ubiquitin ligase for sterol-induced degradation of HMG-CoA reductase.
    Jiang LY, Jiang W, Tian N, Xiong YN, Liu J, Wei J, Wu KY, Luo J, Shi XJ, Song BL.
    J Biol Chem; 2018 Mar 16; 293(11):4047-4055. PubMed ID: 29374057
    [Abstract] [Full Text] [Related]

  • 4. Sterol-regulated degradation of Insig-1 mediated by the membrane-bound ubiquitin ligase gp78.
    Lee JN, Song B, DeBose-Boyd RA, Ye J.
    J Biol Chem; 2006 Dec 22; 281(51):39308-15. PubMed ID: 17043353
    [Abstract] [Full Text] [Related]

  • 5. Ufd1 is a cofactor of gp78 and plays a key role in cholesterol metabolism by regulating the stability of HMG-CoA reductase.
    Cao J, Wang J, Qi W, Miao HH, Wang J, Ge L, DeBose-Boyd RA, Tang JJ, Li BL, Song BL.
    Cell Metab; 2007 Aug 22; 6(2):115-28. PubMed ID: 17681147
    [Abstract] [Full Text] [Related]

  • 6. Differential regulation of HMG-CoA reductase and Insig-1 by enzymes of the ubiquitin-proteasome system.
    Tsai YC, Leichner GS, Pearce MM, Wilson GL, Wojcikiewicz RJ, Roitelman J, Weissman AM.
    Mol Biol Cell; 2012 Dec 22; 23(23):4484-94. PubMed ID: 23087214
    [Abstract] [Full Text] [Related]

  • 7. Membrane-associated ubiquitin ligase complex containing gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
    Jo Y, Sguigna PV, DeBose-Boyd RA.
    J Biol Chem; 2011 Apr 29; 286(17):15022-31. PubMed ID: 21343306
    [Abstract] [Full Text] [Related]

  • 8. Control of cholesterol synthesis through regulated ER-associated degradation of HMG CoA reductase.
    Jo Y, Debose-Boyd RA.
    Crit Rev Biochem Mol Biol; 2010 Jun 29; 45(3):185-98. PubMed ID: 20482385
    [Abstract] [Full Text] [Related]

  • 9. The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1.
    Menzies SA, Volkmar N, van den Boomen DJ, Timms RT, Dickson AS, Nathan JA, Lehner PJ.
    Elife; 2018 Dec 13; 7():. PubMed ID: 30543180
    [Abstract] [Full Text] [Related]

  • 10. Insig-mediated, sterol-accelerated degradation of the membrane domain of hamster 3-hydroxy-3-methylglutaryl-coenzyme A reductase in insect cells.
    Nguyen AD, Lee SH, DeBose-Boyd RA.
    J Biol Chem; 2009 Sep 25; 284(39):26778-88. PubMed ID: 19638338
    [Abstract] [Full Text] [Related]

  • 11. Sterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from membranes of permeabilized cells.
    Elsabrouty R, Jo Y, Dinh TT, DeBose-Boyd RA.
    Mol Biol Cell; 2013 Nov 25; 24(21):3300-8. PubMed ID: 24025715
    [Abstract] [Full Text] [Related]

  • 12. Underlying mechanisms for sterol-induced ubiquitination and ER-associated degradation of HMG CoA reductase.
    Johnson BM, DeBose-Boyd RA.
    Semin Cell Dev Biol; 2018 Sep 25; 81():121-128. PubMed ID: 29107682
    [Abstract] [Full Text] [Related]

  • 13. Ancient ubiquitous protein-1 mediates sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl CoA reductase in lipid droplet-associated endoplasmic reticulum membranes.
    Jo Y, Hartman IZ, DeBose-Boyd RA.
    Mol Biol Cell; 2013 Feb 25; 24(3):169-83. PubMed ID: 23223569
    [Abstract] [Full Text] [Related]

  • 14. Accelerated degradation of HMG CoA reductase mediated by binding of insig-1 to its sterol-sensing domain.
    Sever N, Yang T, Brown MS, Goldstein JL, DeBose-Boyd RA.
    Mol Cell; 2003 Jan 25; 11(1):25-33. PubMed ID: 12535518
    [Abstract] [Full Text] [Related]

  • 15. Ubiquitination of 3-hydroxy-3-methylglutaryl-CoA reductase in permeabilized cells mediated by cytosolic E1 and a putative membrane-bound ubiquitin ligase.
    Song BL, DeBose-Boyd RA.
    J Biol Chem; 2004 Jul 02; 279(27):28798-806. PubMed ID: 15090540
    [Abstract] [Full Text] [Related]

  • 16. Insig-dependent ubiquitination and degradation of mammalian 3-hydroxy-3-methylglutaryl-CoA reductase stimulated by sterols and geranylgeraniol.
    Sever N, Song BL, Yabe D, Goldstein JL, Brown MS, DeBose-Boyd RA.
    J Biol Chem; 2003 Dec 26; 278(52):52479-90. PubMed ID: 14563840
    [Abstract] [Full Text] [Related]

  • 17. Lipid-regulated degradation of HMG-CoA reductase and Insig-1 through distinct mechanisms in insect cells.
    Faulkner RA, Nguyen AD, Jo Y, DeBose-Boyd RA.
    J Lipid Res; 2013 Apr 26; 54(4):1011-22. PubMed ID: 23403031
    [Abstract] [Full Text] [Related]

  • 18. Mutations within the membrane domain of HMG-CoA reductase confer resistance to sterol-accelerated degradation.
    Lee PC, Nguyen AD, Debose-Boyd RA.
    J Lipid Res; 2007 Feb 26; 48(2):318-27. PubMed ID: 17090658
    [Abstract] [Full Text] [Related]

  • 19. Feedback regulation of cholesterol synthesis: sterol-accelerated ubiquitination and degradation of HMG CoA reductase.
    DeBose-Boyd RA.
    Cell Res; 2008 Jun 26; 18(6):609-21. PubMed ID: 18504457
    [Abstract] [Full Text] [Related]

  • 20. Identification of SVIP as an endogenous inhibitor of endoplasmic reticulum-associated degradation.
    Ballar P, Zhong Y, Nagahama M, Tagaya M, Shen Y, Fang S.
    J Biol Chem; 2007 Nov 23; 282(47):33908-14. PubMed ID: 17872946
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 22.