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Journal Abstract Search

186 related items for PubMed ID: 1617665

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  • 4. Antitumor agents. 174. 2',3',4',5,6,7-Substituted 2-phenyl-1,8-naphthyridin-4-ones: their synthesis, cytotoxicity, and inhibition of tubulin polymerization.
    Chen K, Kuo SC, Hsieh MC, Mauger A, Lin CM, Hamel E, Lee KH.
    J Med Chem; 1997 Jul 04; 40(14):2266-75. PubMed ID: 9216846
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  • 5. Derivatives of 5,6-diphenylpyridazin-3-one: synthetic antimitotic agents which interact with plant and mammalian tubulin at a new drug-binding site.
    Batra JK, Powers LJ, Hess FD, Hamel E.
    Cancer Res; 1986 Apr 04; 46(4 Pt 2):1889-93. PubMed ID: 3948171
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  • 7. Tubulin-perturbing naphthoquinone spiroketals.
    Balachandran R, Hopkins TD, Thomas CA, Wipf P, Day BW.
    Chem Biol Drug Des; 2008 Feb 04; 71(2):117-24. PubMed ID: 18194192
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  • 8. A-204197, a new tubulin-binding agent with antimitotic activity in tumor cell lines resistant to known microtubule inhibitors.
    Tahir SK, Han EK, Credo B, Jae HS, Pietenpol JA, Scatena CD, Wu-Wong JR, Frost D, Sham H, Rosenberg SH, Ng SC.
    Cancer Res; 2001 Jul 15; 61(14):5480-5. PubMed ID: 11454695
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  • 9. BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo.
    Kuo CC, Hsieh HP, Pan WY, Chen CP, Liou JP, Lee SJ, Chang YL, Chen LT, Chen CT, Chang JY.
    Cancer Res; 2004 Jul 01; 64(13):4621-8. PubMed ID: 15231674
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  • 10. Antimitotic antifungal compound benomyl inhibits brain microtubule polymerization and dynamics and cancer cell proliferation at mitosis, by binding to a novel site in tubulin.
    Gupta K, Bishop J, Peck A, Brown J, Wilson L, Panda D.
    Biochemistry; 2004 Jun 01; 43(21):6645-55. PubMed ID: 15157098
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  • 11. Oxadiazole derivatives as a novel class of antimitotic agents: Synthesis, inhibition of tubulin polymerization, and activity in tumor cell lines.
    Ouyang X, Piatnitski EL, Pattaropong V, Chen X, He HY, Kiselyov AS, Velankar A, Kawakami J, Labelle M, Smith L, Lohman J, Lee SP, Malikzay A, Fleming J, Gerlak J, Wang Y, Rosler RL, Zhou K, Mitelman S, Camara M, Surguladze D, Doody JF, Tuma MC.
    Bioorg Med Chem Lett; 2006 Mar 01; 16(5):1191-6. PubMed ID: 16377187
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  • 12. Structure-function studies with derivatives of 6-benzyl-1,3-benzodioxole, a new class of synthetic compounds which inhibit tubulin polymerization and mitosis.
    Batra JK, Jurd L, Hamel E.
    Mol Pharmacol; 1985 Jan 01; 27(1):94-102. PubMed ID: 3965931
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  • 13. Halichondrin B and homohalichondrin B, marine natural products binding in the vinca domain of tubulin. Discovery of tubulin-based mechanism of action by analysis of differential cytotoxicity data.
    Bai RL, Paull KD, Herald CL, Malspeis L, Pettit GR, Hamel E.
    J Biol Chem; 1991 Aug 25; 266(24):15882-9. PubMed ID: 1874739
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  • 14. Structure-based virtual screening of novel tubulin inhibitors and their characterization as anti-mitotic agents.
    Kim ND, Park ES, Kim YH, Moon SK, Lee SS, Ahn SK, Yu DY, No KT, Kim KH.
    Bioorg Med Chem; 2010 Oct 01; 18(19):7092-100. PubMed ID: 20810285
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  • 15. 2-aroylindoles, a novel class of potent, orally active small molecule tubulin inhibitors.
    Beckers T, Reissmann T, Schmidt M, Burger AM, Fiebig HH, Vanhoefer U, Pongratz H, Hufsky H, Hockemeyer J, Frieser M, Mahboobi S.
    Cancer Res; 2002 Jun 01; 62(11):3113-9. PubMed ID: 12036922
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  • 16. Spongistatin 1, a highly cytotoxic, sponge-derived, marine natural product that inhibits mitosis, microtubule assembly, and the binding of vinblastine to tubulin.
    Bai R, Cichacz ZA, Herald CL, Pettit GR, Hamel E.
    Mol Pharmacol; 1993 Oct 01; 44(4):757-66. PubMed ID: 8232226
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  • 18. Tricyclic pyrone analogs: a new synthetic class of bifunctional anticancer drugs that inhibit nucleoside transport, microtubule assembly, the viability of leukemic cells in vitro and the growth of solid tumors in vivo.
    Perchellet EM, Ladesich JB, Magill MJ, Chen Y, Hua DH, Perchellet JP.
    Anticancer Drugs; 1999 Jun 01; 10(5):489-504. PubMed ID: 10477169
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