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181 related items for PubMed ID: 16179586

  • 1. Activation of the sphingosine kinase-signaling pathway by high glucose mediates the proinflammatory phenotype of endothelial cells.
    Wang L, Xing XP, Holmes A, Wadham C, Gamble JR, Vadas MA, Xia P.
    Circ Res; 2005 Oct 28; 97(9):891-9. PubMed ID: 16179586
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  • 3. Activation of sphingosine kinase mediates suppressive effect of interleukin-6 on human multiple myeloma cell apoptosis.
    Li QF, Wu CT, Duan HF, Sun HY, Wang H, Lu ZZ, Zhang QW, Liu HJ, Wang LS.
    Br J Haematol; 2007 Sep 28; 138(5):632-9. PubMed ID: 17686057
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  • 5. Sphingosine kinase 1 is essential for proteinase-activated receptor-1 signalling in epithelial and endothelial cells.
    Billich A, Urtz N, Reuschel R, Baumruker T.
    Int J Biochem Cell Biol; 2009 Jul 28; 41(7):1547-55. PubMed ID: 19162217
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  • 6. Glabridin suppresses intercellular adhesion molecule-1 expression in tumor necrosis factor-alpha-stimulated human umbilical vein endothelial cells by blocking sphingosine kinase pathway: implications of Akt, extracellular signal-regulated kinase, and nuclear factor-kappaB/Rel signaling pathways.
    Kang JS, Yoon YD, Han MH, Han SB, Lee K, Lee KH, Park SK, Kim HM.
    Mol Pharmacol; 2006 Mar 28; 69(3):941-9. PubMed ID: 16354764
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  • 7. Selective inhibition of protein kinase Cbeta2 prevents acute effects of high glucose on vascular cell adhesion molecule-1 expression in human endothelial cells.
    Kouroedov A, Eto M, Joch H, Volpe M, Lüscher TF, Cosentino F.
    Circulation; 2004 Jul 06; 110(1):91-6. PubMed ID: 15210597
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  • 8. Deletion of the sphingosine kinase-1 gene influences cell fate during hypoxia and glucose deprivation in adult mouse cardiomyocytes.
    Tao R, Zhang J, Vessey DA, Honbo N, Karliner JS.
    Cardiovasc Res; 2007 Apr 01; 74(1):56-63. PubMed ID: 17320845
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  • 9. Apoptosis signal-regulating kinase 1 mediates cellular senescence induced by high glucose in endothelial cells.
    Yokoi T, Fukuo K, Yasuda O, Hotta M, Miyazaki J, Takemura Y, Kawamoto H, Ichijo H, Ogihara T.
    Diabetes; 2006 Jun 01; 55(6):1660-5. PubMed ID: 16731828
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  • 10. Berberine prevents hyperglycemia-induced endothelial injury and enhances vasodilatation via adenosine monophosphate-activated protein kinase and endothelial nitric oxide synthase.
    Wang Y, Huang Y, Lam KS, Li Y, Wong WT, Ye H, Lau CW, Vanhoutte PM, Xu A.
    Cardiovasc Res; 2009 Jun 01; 82(3):484-92. PubMed ID: 19251722
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  • 13. High glucose-induced activation of protein kinase signaling pathways in vascular smooth muscle cells: a potential role in the pathogenesis of vascular dysfunction in diabetes (review).
    Srivastava AK.
    Int J Mol Med; 2002 Jan 01; 9(1):85-9. PubMed ID: 11745003
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  • 14. Sphingosine kinase-1 pathway mediates high glucose-induced fibronectin expression in glomerular mesangial cells.
    Lan T, Liu W, Xie X, Xu S, Huang K, Peng J, Shen X, Liu P, Wang L, Xia P, Huang H.
    Mol Endocrinol; 2011 Dec 01; 25(12):2094-105. PubMed ID: 21998146
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  • 15. Modulation of P-glycoprotein function by sphingosine kinase-1 in brain endothelial cells.
    Pilorget A, Demeule M, Barakat S, Marvaldi J, Luis J, Béliveau R.
    J Neurochem; 2007 Mar 01; 100(5):1203-10. PubMed ID: 17316399
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  • 16. Low-dose treatment with atorvastatin leads to anti-oxidative and anti-inflammatory effects in diabetes mellitus.
    Riad A, Du J, Stiehl S, Westermann D, Mohr Z, Sobirey M, Doehner W, Adams V, Pauschinger M, Schultheiss HP, Tschöpe C.
    Eur J Pharmacol; 2007 Aug 27; 569(3):204-11. PubMed ID: 17669395
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  • 17. Curcumin ameliorates diabetic nephropathy by inhibiting the activation of the SphK1-S1P signaling pathway.
    Huang J, Huang K, Lan T, Xie X, Shen X, Liu P, Huang H.
    Mol Cell Endocrinol; 2013 Jan 30; 365(2):231-40. PubMed ID: 23127801
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  • 18. TGFbeta protects mesoangioblasts from apoptosis via sphingosine kinase-1 regulation.
    Donati C, Cencetti F, De Palma C, Rapizzi E, Brunelli S, Cossu G, Clementi E, Bruni P.
    Cell Signal; 2009 Feb 30; 21(2):228-36. PubMed ID: 18983913
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  • 19. Inhibition of NADPH oxidase-related oxidative stress-triggered signaling by honokiol suppresses high glucose-induced human endothelial cell apoptosis.
    Sheu ML, Chiang CK, Tsai KS, Ho FM, Weng TI, Wu HY, Liu SH.
    Free Radic Biol Med; 2008 Jun 15; 44(12):2043-50. PubMed ID: 18423412
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  • 20. Activation of the SPHK/S1P signalling pathway is coupled to muscarinic receptor-dependent regulation of peripheral airways.
    Pfaff M, Powaga N, Akinci S, Schütz W, Banno Y, Wiegand S, Kummer W, Wess J, Haberberger RV.
    Respir Res; 2005 May 31; 6(1):48. PubMed ID: 15927078
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