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164 related items for PubMed ID: 16184031
21. Dipeptide prodrug approach to evade efflux pumps and CYP3A4 metabolism of lopinavir. Patel M, Sheng Y, Mandava NK, Pal D, Mitra AK. Int J Pharm; 2014 Dec 10; 476(1-2):99-107. PubMed ID: 25261710 [Abstract] [Full Text] [Related]
22. ABCB1 1199G>A Polymorphism Affects the Intracellular Accumulation of Antidepressants in LLC-PK1 Recombinant Cell Lines. Gao YL, He B. DNA Cell Biol; 2018 Dec 10; 37(12):1055-1060. PubMed ID: 30256659 [Abstract] [Full Text] [Related]
23. MDR1 synonymous polymorphisms alter transporter specificity and protein stability in a stable epithelial monolayer. Fung KL, Pan J, Ohnuma S, Lund PE, Pixley JN, Kimchi-Sarfaty C, Ambudkar SV, Gottesman MM. Cancer Res; 2014 Jan 15; 74(2):598-608. PubMed ID: 24305879 [Abstract] [Full Text] [Related]
24. Effects of MDR1 (C3435T) Polymorphism on Resistance, Uptake, and Efflux to Antiepileptic Drugs. Shen XM, Cheng J. DNA Cell Biol; 2019 Mar 15; 38(3):250-255. PubMed ID: 30632789 [Abstract] [Full Text] [Related]
25. Evaluation of P-glycoprotein-mediated renal drug interactions in an MDR1-MDCK model. Karyekar CS, Eddington ND, Garimella TS, Gubbins PO, Dowling TC. Pharmacotherapy; 2003 Apr 15; 23(4):436-42. PubMed ID: 12680473 [Abstract] [Full Text] [Related]
28. Evasion of P-gp mediated cellular efflux and permeability enhancement of HIV-protease inhibitor saquinavir by prodrug modification. Jain R, Agarwal S, Majumdar S, Zhu X, Pal D, Mitra AK. Int J Pharm; 2005 Oct 13; 303(1-2):8-19. PubMed ID: 16137847 [Abstract] [Full Text] [Related]
29. Combination of protease inhibitors for the treatment of HIV-1-infected patients: a review of pharmacokinetics and clinical experience. van Heeswijk RP, Veldkamp A, Mulder JW, Meenhorst PL, Lange JM, Beijnen JH, Hoetelmans RM. Antivir Ther; 2001 Dec 13; 6(4):201-29. PubMed ID: 11878403 [Abstract] [Full Text] [Related]
30. A Mathematical simulation to explain the coordinated functions of efflux and metabolism limiting the transport of anti-HIV agents across Caco-2 cells. Patel J, Hussain A, Pal D, Mitra AK. Am J Ther; 2004 Dec 13; 11(2):114-23. PubMed ID: 14999363 [Abstract] [Full Text] [Related]
32. Functional characterization of sodium-dependent multivitamin transporter in MDCK-MDR1 cells and its utilization as a target for drug delivery. Luo S, Kansara VS, Zhu X, Mandava NK, Pal D, Mitra AK. Mol Pharm; 2006 Dec 13; 3(3):329-39. PubMed ID: 16749865 [Abstract] [Full Text] [Related]
33. Interactions of HIV protease inhibitors with ATP-dependent drug export proteins. Gutmann H, Fricker G, Drewe J, Toeroek M, Miller DS. Mol Pharmacol; 1999 Aug 13; 56(2):383-9. PubMed ID: 10419558 [Abstract] [Full Text] [Related]
35. HIV protease inhibitors are inhibitors but not substrates of the human breast cancer resistance protein (BCRP/ABCG2). Gupta A, Zhang Y, Unadkat JD, Mao Q. J Pharmacol Exp Ther; 2004 Jul 13; 310(1):334-41. PubMed ID: 15007102 [Abstract] [Full Text] [Related]
37. Comparative effects on intestinal absorption in situ by P-glycoprotein-modifying HIV protease inhibitors. Richter M, Gyémánt N, Molnár J, Hilgeroth A. Pharm Res; 2004 Oct 13; 21(10):1862-6. PubMed ID: 15553233 [Abstract] [Full Text] [Related]
38. P-glycoprotein limits oral availability, brain, and fetal penetration of saquinavir even with high doses of ritonavir. Huisman MT, Smit JW, Wiltshire HR, Hoetelmans RM, Beijnen JH, Schinkel AH. Mol Pharmacol; 2001 Apr 13; 59(4):806-13. PubMed ID: 11259625 [Abstract] [Full Text] [Related]