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Journal Abstract Search

132 related items for PubMed ID: 1618747

  • 1. Activation of insulin receptor signaling by a single amino acid substitution in the transmembrane domain.
    Longo N, Shuster RC, Griffin LD, Langley SD, Elsas LJ.
    J Biol Chem; 1992 Jun 25; 267(18):12416-9. PubMed ID: 1618747
    [Abstract] [Full Text] [Related]

  • 2. Substitution of the insulin receptor transmembrane domain with the c-neu/erbB2 transmembrane domain constitutively activates the insulin receptor kinase in vitro.
    Yamada K, Goncalves E, Kahn CR, Shoelson SE.
    J Biol Chem; 1992 Jun 25; 267(18):12452-61. PubMed ID: 1352286
    [Abstract] [Full Text] [Related]

  • 3. N-linked oligosaccharide chains of the insulin receptor beta subunit are essential for transmembrane signaling.
    Leconte I, Auzan C, Debant A, Rossi B, Clauser E.
    J Biol Chem; 1992 Aug 25; 267(24):17415-23. PubMed ID: 1324936
    [Abstract] [Full Text] [Related]

  • 4. Insulin receptor kinase domain autophosphorylation regulates receptor enzymatic function.
    Wilden PA, Kahn CR, Siddle K, White MF.
    J Biol Chem; 1992 Aug 15; 267(23):16660-8. PubMed ID: 1322912
    [Abstract] [Full Text] [Related]

  • 5. Enhanced insulin-induced mitogenesis and mitogen-activated protein kinase activities in mutant insulin receptors with substitution of two COOH-terminal tyrosine autophosphorylation sites by phenylalanine.
    Ando A, Momomura K, Tobe K, Yamamoto-Honda R, Sakura H, Tamori Y, Kaburagi Y, Koshio O, Akanuma Y, Yazaki Y.
    J Biol Chem; 1992 Jun 25; 267(18):12788-96. PubMed ID: 1618780
    [Abstract] [Full Text] [Related]

  • 6. Activation of glucose transport by a natural mutation in the human insulin receptor.
    Longo N, Langley SD, Griffin LD, Elsas LJ.
    Proc Natl Acad Sci U S A; 1993 Jan 01; 90(1):60-4. PubMed ID: 8419945
    [Abstract] [Full Text] [Related]

  • 7. Human insulin receptor mutated at threonine 1336 functions normally in Chinese hamster ovary cells.
    Ahn J, Rosen OM, Donner DB.
    J Biol Chem; 1993 Aug 05; 268(22):16839-44. PubMed ID: 8393875
    [Abstract] [Full Text] [Related]

  • 8. Cysteine-524 is not the only residue involved in the formation of disulphide-bonded dimers of the insulin receptor.
    Macaulay SL, Polites M, Hewish DR, Ward CW.
    Biochem J; 1994 Oct 15; 303 ( Pt 2)(Pt 2):575-81. PubMed ID: 7980420
    [Abstract] [Full Text] [Related]

  • 9. The role of insulin receptor kinase domain autophosphorylation in receptor-mediated activities. Analysis with insulin and anti-receptor antibodies.
    Wilden PA, Siddle K, Haring E, Backer JM, White MF, Kahn CR.
    J Biol Chem; 1992 Jul 05; 267(19):13719-27. PubMed ID: 1320027
    [Abstract] [Full Text] [Related]

  • 10. Role of arginine 86 of the insulin receptor in insulin binding and activation of glucose transport.
    Longo N, Langley SD, Still MJ.
    Biochim Biophys Acta; 1998 Mar 12; 1402(1):86-94. PubMed ID: 9551089
    [Abstract] [Full Text] [Related]

  • 11. Two naturally occurring mutant insulin receptors phosphorylate insulin receptor substrate-1 (IRS-1) but fail to mediate the biological effects of insulin. Evidence that IRS-1 phosphorylation is not sufficient for normal insulin action.
    Krook A, Moller DE, Dib K, O'Rahilly S.
    J Biol Chem; 1996 Mar 22; 271(12):7134-40. PubMed ID: 8636149
    [Abstract] [Full Text] [Related]

  • 12. Expression and function of IRS-1 in insulin signal transmission.
    Sun XJ, Miralpeix M, Myers MG, Glasheen EM, Backer JM, Kahn CR, White MF.
    J Biol Chem; 1992 Nov 05; 267(31):22662-72. PubMed ID: 1385403
    [Abstract] [Full Text] [Related]

  • 13. Site-directed mutagenesis of the juxtamembrane domain of the human insulin receptor.
    Kaburagi Y, Momomura K, Yamamoto-Honda R, Tobe K, Tamori Y, Sakura H, Akanuma Y, Yazaki Y, Kadowaki T.
    J Biol Chem; 1993 Aug 05; 268(22):16610-22. PubMed ID: 8393870
    [Abstract] [Full Text] [Related]

  • 14. Replacement of the conserved tyrosine 1210 by phenylalanine in the insulin receptor affects insulin-induced dephosphorylation of focal adhesion kinase but leaves other responses intact.
    Van der Zon GC, Ouwens DM, Dorrestijn J, Maassen JA.
    Biochemistry; 1996 Aug 13; 35(32):10377-82. PubMed ID: 8756693
    [Abstract] [Full Text] [Related]

  • 15. Two sequences flanking the major autophosphorylation site of the insulin receptor are essential for tyrosine kinase activation.
    Leconte I, Clauser E.
    Biochem J; 1995 Mar 01; 306 ( Pt 2)(Pt 2):465-72. PubMed ID: 7887900
    [Abstract] [Full Text] [Related]

  • 16. Substitution of the erbB-2 oncoprotein transmembrane domain activates the insulin receptor and modulates the action of insulin and insulin-receptor substrate 1.
    Cheatham B, Shoelson SE, Yamada K, Goncalves E, Kahn CR.
    Proc Natl Acad Sci U S A; 1993 Aug 01; 90(15):7336-40. PubMed ID: 7688476
    [Abstract] [Full Text] [Related]

  • 17. Mutagenic structure/function analysis of the cytoplasmic cysteines of the insulin receptor.
    Macaulay SL, Polites M, Frenkel MJ, Hewish DR, Ward CW.
    Biochem J; 1995 Mar 15; 306 ( Pt 3)(Pt 3):811-20. PubMed ID: 7702578
    [Abstract] [Full Text] [Related]

  • 18. Optimizing transmembrane domain helicity accelerates insulin receptor internalization and lateral mobility.
    Goncalves E, Yamada K, Thatte HS, Backer JM, Golan DE, Kahn CR, Shoelson SE.
    Proc Natl Acad Sci U S A; 1993 Jun 15; 90(12):5762-6. PubMed ID: 8390680
    [Abstract] [Full Text] [Related]

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