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Journal Abstract Search

316 related items for PubMed ID: 16188892

  • 1. Human topoisomerase IIalpha rapidly relaxes positively supercoiled DNA: implications for enzyme action ahead of replication forks.
    McClendon AK, Rodriguez AC, Osheroff N.
    J Biol Chem; 2005 Nov 25; 280(47):39337-45. PubMed ID: 16188892
    [Abstract] [Full Text] [Related]

  • 2. Bimodal recognition of DNA geometry by human topoisomerase II alpha: preferential relaxation of positively supercoiled DNA requires elements in the C-terminal domain.
    McClendon AK, Gentry AC, Dickey JS, Brinch M, Bendsen S, Andersen AH, Osheroff N.
    Biochemistry; 2008 Dec 16; 47(50):13169-78. PubMed ID: 19053267
    [Abstract] [Full Text] [Related]

  • 3. The geometry of DNA supercoils modulates topoisomerase-mediated DNA cleavage and enzyme response to anticancer drugs.
    McClendon AK, Osheroff N.
    Biochemistry; 2006 Mar 07; 45(9):3040-50. PubMed ID: 16503659
    [Abstract] [Full Text] [Related]

  • 4. Chiral discrimination and writhe-dependent relaxation mechanism of human topoisomerase IIα.
    Seol Y, Gentry AC, Osheroff N, Neuman KC.
    J Biol Chem; 2013 May 10; 288(19):13695-703. PubMed ID: 23508957
    [Abstract] [Full Text] [Related]

  • 5. Recognition of DNA Supercoil Handedness during Catenation Catalyzed by Type II Topoisomerases.
    Dalvie ED, Stacy JC, Neuman KC, Osheroff N.
    Biochemistry; 2022 Oct 04; 61(19):2148-2158. PubMed ID: 36122251
    [Abstract] [Full Text] [Related]

  • 6. Catalytic core of human topoisomerase IIα: insights into enzyme-DNA interactions and drug mechanism.
    Lindsey RH, Pendleton M, Ashley RE, Mercer SL, Deweese JE, Osheroff N.
    Biochemistry; 2014 Oct 21; 53(41):6595-602. PubMed ID: 25280269
    [Abstract] [Full Text] [Related]

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  • 8. A high-throughput fluorescence anisotropy-based assay for human topoisomerase II β-catalyzed ATP-dependent supercoiled DNA relaxation.
    Shapiro AB, Austin CA.
    Anal Biochem; 2014 Mar 01; 448():23-9. PubMed ID: 24309019
    [Abstract] [Full Text] [Related]

  • 9. Metal ion interactions in the DNA cleavage/ligation active site of human topoisomerase IIalpha.
    Deweese JE, Guengerich FP, Burgin AB, Osheroff N.
    Biochemistry; 2009 Sep 29; 48(38):8940-7. PubMed ID: 19697956
    [Abstract] [Full Text] [Related]

  • 10. Activities of gyrase and topoisomerase IV on positively supercoiled DNA.
    Ashley RE, Dittmore A, McPherson SA, Turnbough CL, Neuman KC, Osheroff N.
    Nucleic Acids Res; 2017 Sep 19; 45(16):9611-9624. PubMed ID: 28934496
    [Abstract] [Full Text] [Related]

  • 11. Mutation of cysteine residue 455 to alanine in human topoisomerase IIalpha confers hypersensitivity to quinones: enhancing DNA scission by closing the N-terminal protein gate.
    Bender RP, Osheroff N.
    Chem Res Toxicol; 2007 Jun 19; 20(6):975-81. PubMed ID: 17516663
    [Abstract] [Full Text] [Related]

  • 12. Preferential relaxation of positively supercoiled DNA by E. coli topoisomerase IV in single-molecule and ensemble measurements.
    Crisona NJ, Strick TR, Bensimon D, Croquette V, Cozzarelli NR.
    Genes Dev; 2000 Nov 15; 14(22):2881-92. PubMed ID: 11090135
    [Abstract] [Full Text] [Related]

  • 13. Varying levels of positive and negative supercoiling differently affect the efficiency with which topoisomerase II catenates and decatenates DNA.
    Roca J.
    J Mol Biol; 2001 Jan 19; 305(3):441-50. PubMed ID: 11152602
    [Abstract] [Full Text] [Related]

  • 14. Cleavage of plasmid DNA by eukaryotic topoisomerase II.
    Bandele OJ, Osheroff N.
    Methods Mol Biol; 2009 Jan 19; 582():39-47. PubMed ID: 19763940
    [Abstract] [Full Text] [Related]

  • 15. DNA supercoiling during ATP-dependent DNA translocation by the type I restriction enzyme EcoAI.
    Janscak P, Bickle TA.
    J Mol Biol; 2000 Jan 28; 295(4):1089-99. PubMed ID: 10656812
    [Abstract] [Full Text] [Related]

  • 16. Metnase promotes restart and repair of stalled and collapsed replication forks.
    De Haro LP, Wray J, Williamson EA, Durant ST, Corwin L, Gentry AC, Osheroff N, Lee SH, Hromas R, Nickoloff JA.
    Nucleic Acids Res; 2010 Sep 28; 38(17):5681-91. PubMed ID: 20457750
    [Abstract] [Full Text] [Related]

  • 17. Chromosome length influences replication-induced topological stress.
    Kegel A, Betts-Lindroos H, Kanno T, Jeppsson K, Ström L, Katou Y, Itoh T, Shirahige K, Sjögren C.
    Nature; 2011 Mar 17; 471(7338):392-6. PubMed ID: 21368764
    [Abstract] [Full Text] [Related]

  • 18. Impact of the C-terminal domain of topoisomerase IIalpha on the DNA cleavage activity of the human enzyme.
    Dickey JS, Osheroff N.
    Biochemistry; 2005 Aug 30; 44(34):11546-54. PubMed ID: 16114891
    [Abstract] [Full Text] [Related]

  • 19. The geometry of DNA supercoils modulates the DNA cleavage activity of human topoisomerase I.
    Gentry AC, Juul S, Veigaard C, Knudsen BR, Osheroff N.
    Nucleic Acids Res; 2011 Feb 30; 39(3):1014-22. PubMed ID: 20855291
    [Abstract] [Full Text] [Related]

  • 20. Interaction in vitro of type III intermediate filament proteins with supercoiled plasmid DNA and modulation of eukaryotic DNA topoisomerase I and II activities.
    Li G, Tolstonog GV, Sabasch M, Traub P.
    DNA Cell Biol; 2002 Oct 30; 21(10):743-69. PubMed ID: 12443544
    [Abstract] [Full Text] [Related]

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