These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Tricyclic pyrazoles. 3. Synthesis, biological evaluation, and molecular modeling of analogues of the cannabinoid antagonist 8-chloro-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide. Murineddu G, Ruiu S, Loriga G, Manca I, Lazzari P, Reali R, Pani L, Toma L, Pinna GA. J Med Chem; 2005 Nov 17; 48(23):7351-62. PubMed ID: 16279795 [Abstract] [Full Text] [Related]
4. Evaluation of the in vivo receptor occupancy for the behavioral effects of cannabinoids using a radiolabeled cannabinoid receptor agonist, R-[125/131I]AM2233. Dhawan J, Deng H, Gatley SJ, Makriyannis A, Akinfeleye T, Bruneus M, Dimaio AA, Gifford AN. Synapse; 2006 Aug 17; 60(2):93-101. PubMed ID: 16715483 [Abstract] [Full Text] [Related]
11. Synthesis and activity of 1,3,5-triphenylimidazolidine-2,4-diones and 1,3,5-triphenyl-2-thioxoimidazolidin-4-ones: characterization of new CB1 cannabinoid receptor inverse agonists/antagonists. Muccioli GG, Wouters J, Charlier C, Scriba GK, Pizza T, Di Pace P, De Martino P, Poppitz W, Poupaert JH, Lambert DM. J Med Chem; 2006 Feb 09; 49(3):872-82. PubMed ID: 16451053 [Abstract] [Full Text] [Related]
12. Cannabinoid-mediated elevation of intracellular calcium: a structure-activity relationship. Rao GK, Kaminski NE. J Pharmacol Exp Ther; 2006 May 09; 317(2):820-9. PubMed ID: 16436496 [Abstract] [Full Text] [Related]
13. Structural modifications of the cannabinoid side chain towards C3-aryl and 1',1'-cycloalkyl-1'-cyano cannabinoids. Papahatjis DP, Nahmias VR, Andreou T, Fan P, Makriyannis A. Bioorg Med Chem Lett; 2006 Mar 15; 16(6):1616-20. PubMed ID: 16387492 [Abstract] [Full Text] [Related]
15. Cannabilactones: a novel class of CB2 selective agonists with peripheral analgesic activity. Khanolkar AD, Lu D, Ibrahim M, Duclos RI, Thakur GA, Malan TP, Porreca F, Veerappan V, Tian X, George C, Parrish DA, Papahatjis DP, Makriyannis A. J Med Chem; 2007 Dec 27; 50(26):6493-500. PubMed ID: 18038967 [Abstract] [Full Text] [Related]
16. Development of CoMFA and CoMSIA models of affinity and selectivity for indole ligands of cannabinoid CB1 and CB2 receptors. De Freitas GB, da Silva LL, Romeiro NC, Fraga CA. Eur J Med Chem; 2009 Jun 27; 44(6):2482-96. PubMed ID: 19249138 [Abstract] [Full Text] [Related]
17. Synthesis and in vitro autoradiographic evaluation of a novel high-affinity radioiodinated ligand for imaging brain cannabinoid subtype-1 receptors. Donohue SR, Varnäs K, Jia Z, Gulyás B, Pike VW, Halldin C. Bioorg Med Chem Lett; 2009 Nov 01; 19(21):6209-12. PubMed ID: 19767206 [Abstract] [Full Text] [Related]