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Journal Abstract Search

503 related items for PubMed ID: 16198562

  • 1. Synthesis and structure-activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors.
    Ouyang X, Chen X, Piatnitski EL, Kiselyov AS, He HY, Mao Y, Pattaropong V, Yu Y, Kim KH, Kincaid J, Smith L, Wong WC, Lee SP, Milligan DL, Malikzay A, Fleming J, Gerlak J, Deevi D, Doody JF, Chiang HH, Patel SN, Wang Y, Rolser RL, Kussie P, Labelle M, Tuma MC.
    Bioorg Med Chem Lett; 2005 Dec 01; 15(23):5154-9. PubMed ID: 16198562
    [Abstract] [Full Text] [Related]

  • 2. 1,5-Disubstituted 1,2,3-triazoles as cis-restricted analogues of combretastatin A-4: Synthesis, molecular modeling and evaluation as cytotoxic agents and inhibitors of tubulin.
    Odlo K, Hentzen J, dit Chabert JF, Ducki S, Gani OA, Sylte I, Skrede M, Flørenes VA, Hansen TV.
    Bioorg Med Chem; 2008 May 01; 16(9):4829-38. PubMed ID: 18396050
    [Abstract] [Full Text] [Related]

  • 3. 9-Benzylidene-naphtho[2,3-b]thiophen-4-ones as novel antimicrotubule agents-synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Zuse A, Schmidt P, Baasner S, Böhm KJ, Müller K, Gerlach M, Günther EG, Unger E, Prinz H.
    J Med Chem; 2006 Dec 28; 49(26):7816-25. PubMed ID: 17181164
    [Abstract] [Full Text] [Related]

  • 4. 5-Amino-2-aroylquinolines as highly potent tubulin polymerization inhibitors.
    Nien CY, Chen YC, Kuo CC, Hsieh HP, Chang CY, Wu JS, Wu SY, Liou JP, Chang JY.
    J Med Chem; 2010 Mar 11; 53(5):2309-13. PubMed ID: 20148562
    [Abstract] [Full Text] [Related]

  • 5. 4- and 5-aroylindoles as novel classes of potent antitubulin agents.
    Liou JP, Wu CY, Hsieh HP, Chang CY, Chen CM, Kuo CC, Chang JY.
    J Med Chem; 2007 Sep 06; 50(18):4548-52. PubMed ID: 17685504
    [Abstract] [Full Text] [Related]

  • 6. 2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
    Chang JY, Yang MF, Chang CY, Chen CM, Kuo CC, Liou JP.
    J Med Chem; 2006 Oct 19; 49(21):6412-5. PubMed ID: 17034147
    [Abstract] [Full Text] [Related]

  • 7. Synthesis and biological evaluation of 1-phenyl-1,2,3,4-dihydroisoquinoline compounds as tubulin polymerization inhibitors.
    Zheng CH, Chen J, Liu J, Zhou XT, Liu N, Shi D, Huang JJ, Lv JG, Zhu J, Zhou YJ.
    Arch Pharm (Weinheim); 2012 Jun 19; 345(6):454-62. PubMed ID: 22415658
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents.
    Romagnoli R, Baraldi PG, Pavani MG, Tabrizi MA, Preti D, Fruttarolo F, Piccagli L, Jung MK, Hamel E, Borgatti M, Gambari R.
    J Med Chem; 2006 Jun 29; 49(13):3906-15. PubMed ID: 16789746
    [Abstract] [Full Text] [Related]

  • 9. Synthesis, biological evaluation, and structure-activity relationships of new tubulin polymerization inhibitors based on 5-amino-1,2,4-triazole scaffold.
    Yang F, Chen L, Lai JM, Jian XE, Lv DX, Yuan LL, Liu YX, Liang FT, Zheng XL, Li XL, Wei LY, You WW, Zhao PL.
    Bioorg Med Chem Lett; 2021 Apr 15; 38():127880. PubMed ID: 33636303
    [Abstract] [Full Text] [Related]

  • 10. Synthesis, biological evaluation and molecular modeling of 1,2,3-triazole analogs of combretastatin A-1.
    Akselsen OW, Odlo K, Cheng JJ, Maccari G, Botta M, Hansen TV.
    Bioorg Med Chem; 2012 Jan 01; 20(1):234-42. PubMed ID: 22137934
    [Abstract] [Full Text] [Related]

  • 11. Molecular modelling studies on Arylthioindoles as potent inhibitors of tubulin polymerization.
    Coluccia A, Sabbadin D, Brancale A.
    Eur J Med Chem; 2011 Aug 01; 46(8):3519-25. PubMed ID: 21621885
    [Abstract] [Full Text] [Related]

  • 12. Synthesis, molecular modeling and biological evaluation of guanidine derivatives as novel antitubulin agents.
    Qian Y, Zhang HJ, Lv PC, Zhu HL.
    Bioorg Med Chem; 2010 Dec 01; 18(23):8218-25. PubMed ID: 21036623
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and biological evaluation of a series of podophyllotoxins derivatives as a class of potent antitubulin agents.
    Liu Y, Wei D, Zhao Y, Cheng W, Lu Y, Ma Y, Li X, Han C, Wei Y, Cao H, Zhao C.
    Bioorg Med Chem; 2012 Nov 01; 20(21):6285-95. PubMed ID: 23022053
    [Abstract] [Full Text] [Related]

  • 14. Benzopyridooxathiazepine derivatives as novel potent antimitotic agents.
    Gallet S, Flouquet N, Carato P, Pfeiffer B, Renard P, Léonce S, Pierré A, Berthelot P, Lebegue N.
    Bioorg Med Chem; 2009 Feb 01; 17(3):1132-8. PubMed ID: 19162484
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and biological evaluation of 1,2,3-triazole linked aminocombretastatin conjugates as mitochondrial mediated apoptosis inducers.
    Kamal A, Shaik B, Nayak VL, Nagaraju B, Kapure JS, Shaheer Malik M, Shaik TB, Prasad B.
    Bioorg Med Chem; 2014 Oct 01; 22(19):5155-67. PubMed ID: 25192811
    [Abstract] [Full Text] [Related]

  • 16. Replacement of the double bond of antitubulin chalcones with triazoles and tetrazoles: Synthesis and biological evaluation.
    Mesenzani O, Massarotti A, Giustiniano M, Pirali T, Bevilacqua V, Caldarelli A, Canonico P, Sorba G, Novellino E, Genazzani AA, Tron GC.
    Bioorg Med Chem Lett; 2011 Jan 15; 21(2):764-8. PubMed ID: 21167709
    [Abstract] [Full Text] [Related]

  • 17. [4-(imidazol-1-yl)thiazol-2-yl]phenylamines. A novel class of highly potent colchicine site binding tubulin inhibitors: synthesis and cytotoxic activity on selected human cancer cell lines.
    Mahboobi S, Sellmer A, Höcher H, Eichhorn E, Bär T, Schmidt M, Maier T, Stadlwieser JF, Beckers TL.
    J Med Chem; 2006 Sep 21; 49(19):5769-76. PubMed ID: 16970401
    [Abstract] [Full Text] [Related]

  • 18. Design, synthesis and evaluation of antiproliferative and antitubulin activities of 5-methyl-4-aryl-3-(4-arylpiperazine-1-carbonyl)-4H-1,2,4-triazoles.
    Wang C, Li Y, Liu T, Wang Z, Zhang Y, Bao K, Wu Y, Guan Q, Zuo D, Zhang W.
    Bioorg Chem; 2020 Nov 21; 104():103909. PubMed ID: 33142419
    [Abstract] [Full Text] [Related]

  • 19. Synthesis, antiproliferative, anti-tubulin activity, and docking study of new 1,2,4-triazoles as potential combretastatin analogues.
    Mustafa M, Abdelhamid D, Abdelhafez EMN, Ibrahim MAA, Gamal-Eldeen AM, Aly OM.
    Eur J Med Chem; 2017 Dec 01; 141():293-305. PubMed ID: 29031074
    [Abstract] [Full Text] [Related]

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