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237 related items for PubMed ID: 16211089

  • 1. Overexpression of von Hippel-Lindau tumor suppressor protein and antisense HIF-1alpha eradicates gliomas.
    Sun X, Liu M, Wei Y, Liu F, Zhi X, Xu R, Krissansen GW.
    Cancer Gene Ther; 2006 Apr; 13(4):428-35. PubMed ID: 16211089
    [Abstract] [Full Text] [Related]

  • 2. Regression of solid tumors by engineered overexpression of von Hippel-Lindau tumor suppressor protein and antisense hypoxia-inducible factor-1alpha.
    Sun X, Kanwar JR, Leung E, Vale M, Krissansen GW.
    Gene Ther; 2003 Dec; 10(25):2081-9. PubMed ID: 14595381
    [Abstract] [Full Text] [Related]

  • 3. Overexpression of von Hippel-Lindau protein synergizes with doxorubicin to suppress hepatocellular carcinoma in mice.
    Wang J, Ma Y, Jiang H, Zhu H, Liu L, Sun B, Pan S, Krissansen GW, Sun X.
    J Hepatol; 2011 Aug; 55(2):359-68. PubMed ID: 21168458
    [Abstract] [Full Text] [Related]

  • 4. Identification of cyclin D1 and other novel targets for the von Hippel-Lindau tumor suppressor gene by expression array analysis and investigation of cyclin D1 genotype as a modifier in von Hippel-Lindau disease.
    Zatyka M, da Silva NF, Clifford SC, Morris MR, Wiesener MS, Eckardt KU, Houlston RS, Richards FM, Latif F, Maher ER.
    Cancer Res; 2002 Jul 01; 62(13):3803-11. PubMed ID: 12097293
    [Abstract] [Full Text] [Related]

  • 5. Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway.
    Carroll VA, Ashcroft M.
    Cancer Res; 2006 Jun 15; 66(12):6264-70. PubMed ID: 16778202
    [Abstract] [Full Text] [Related]

  • 6. Mutations of the von Hippel-Lindau gene confer increased susceptibility to natural killer cells of clear-cell renal cell carcinoma.
    Perier A, Fregni G, Wittnebel S, Gad S, Allard M, Gervois N, Escudier B, Azzarone B, Caignard A.
    Oncogene; 2011 Jun 09; 30(23):2622-32. PubMed ID: 21258414
    [Abstract] [Full Text] [Related]

  • 7. Estrogen receptor α is a novel target of the Von Hippel-Lindau protein and is responsible for the proliferation of VHL-deficient cells under hypoxic conditions.
    Jung YS, Lee SJ, Yoon MH, Ha NC, Park BJ.
    Cell Cycle; 2012 Dec 01; 11(23):4462-73. PubMed ID: 23159849
    [Abstract] [Full Text] [Related]

  • 8. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
    Krieg M, Haas R, Brauch H, Acker T, Flamme I, Plate KH.
    Oncogene; 2000 Nov 16; 19(48):5435-43. PubMed ID: 11114720
    [Abstract] [Full Text] [Related]

  • 9. Antisense-thioredoxin inhibits angiogenesis via pVHL-mediated hypoxia-inducible factor-1alpha degradation.
    Kim WJ, Cho H, Lee SW, Kim YJ, Kim KW.
    Int J Oncol; 2005 Apr 16; 26(4):1049-52. PubMed ID: 15754001
    [Abstract] [Full Text] [Related]

  • 10. The von Hippel-Lindau tumor suppressor gene and kidney cancer.
    Kaelin WG.
    Clin Cancer Res; 2004 Sep 15; 10(18 Pt 2):6290S-5S. PubMed ID: 15448019
    [Abstract] [Full Text] [Related]

  • 11. Antiangiogenic activity of phthalides-enriched Angelica Sinensis extract by suppressing WSB-1/pVHL/HIF-1α/VEGF signaling in bladder cancer.
    Chen MC, Hsu WL, Chang WL, Chou TC.
    Sci Rep; 2017 Jul 14; 7(1):5376. PubMed ID: 28710377
    [Abstract] [Full Text] [Related]

  • 12. Expression of hypoxia-inducible factor 1alpha, hypoxia-inducible factor 2alpha, and von Hippel-Lindau protein in epithelial ovarian neoplasms and allelic loss of von Hippel-Lindau gene: nuclear expression of hypoxia-inducible factor 1alpha is an independent prognostic factor in ovarian carcinoma.
    Osada R, Horiuchi A, Kikuchi N, Yoshida J, Hayashi A, Ota M, Katsuyama Y, Melillo G, Konishi I.
    Hum Pathol; 2007 Sep 14; 38(9):1310-20. PubMed ID: 17555795
    [Abstract] [Full Text] [Related]

  • 13. Renal cyst development in mice with conditional inactivation of the von Hippel-Lindau tumor suppressor.
    Rankin EB, Tomaszewski JE, Haase VH.
    Cancer Res; 2006 Mar 01; 66(5):2576-83. PubMed ID: 16510575
    [Abstract] [Full Text] [Related]

  • 14. Runx2 protein stabilizes hypoxia-inducible factor-1α through competition with von Hippel-Lindau protein (pVHL) and stimulates angiogenesis in growth plate hypertrophic chondrocytes.
    Lee SH, Che X, Jeong JH, Choi JY, Lee YJ, Lee YH, Bae SC, Lee YM.
    J Biol Chem; 2012 Apr 27; 287(18):14760-71. PubMed ID: 22351759
    [Abstract] [Full Text] [Related]

  • 15. EAF2 loss enhances angiogenic effects of Von Hippel-Lindau heterozygosity on the murine liver and prostate.
    Pascal LE, Ai J, Rigatti LH, Lipton AK, Xiao W, Gnarra JR, Wang Z.
    Angiogenesis; 2011 Sep 27; 14(3):331-43. PubMed ID: 21638067
    [Abstract] [Full Text] [Related]

  • 16. Stromal cell-derived factor-1alpha and CXCR4 expression in hemangioblastoma and clear cell-renal cell carcinoma: von Hippel-Lindau loss-of-function induces expression of a ligand and its receptor.
    Zagzag D, Krishnamachary B, Yee H, Okuyama H, Chiriboga L, Ali MA, Melamed J, Semenza GL.
    Cancer Res; 2005 Jul 15; 65(14):6178-88. PubMed ID: 16024619
    [Abstract] [Full Text] [Related]

  • 17. The von Hippel-Lindau tumor suppressor protein and clear cell renal carcinoma.
    Kaelin WG.
    Clin Cancer Res; 2007 Jan 15; 13(2 Pt 2):680s-684s. PubMed ID: 17255293
    [Abstract] [Full Text] [Related]

  • 18. In vitro and in vivo models analyzing von Hippel-Lindau disease-specific mutations.
    Rathmell WK, Hickey MM, Bezman NA, Chmielecki CA, Carraway NC, Simon MC.
    Cancer Res; 2004 Dec 01; 64(23):8595-603. PubMed ID: 15574766
    [Abstract] [Full Text] [Related]

  • 19. Endolymphatic sac tumors in patients with and without von Hippel-Lindau disease: the role of genetic mutation, von Hippel-Lindau protein, and hypoxia inducible factor-1alpha expression.
    Jensen RL, Gillespie D, House P, Layfield L, Shelton C.
    J Neurosurg; 2004 Mar 01; 100(3):488-97. PubMed ID: 15035285
    [Abstract] [Full Text] [Related]

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