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Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

127 related items for PubMed ID: 16213716

  • 1. 3-(5-Chloro-2,4-dihydroxyphenyl)-pyrazole-4-carboxamides as inhibitors of the Hsp90 molecular chaperone.
    Brough PA, Barril X, Beswick M, Dymock BW, Drysdale MJ, Wright L, Grant K, Massey A, Surgenor A, Workman P.
    Bioorg Med Chem Lett; 2005 Dec 01; 15(23):5197-201. PubMed ID: 16213716
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  • 2. Dihydroxylphenyl amides as inhibitors of the Hsp90 molecular chaperone.
    Kung PP, Funk L, Meng J, Collins M, Zhou JZ, Johnson MC, Ekker A, Wang J, Mehta P, Yin MJ, Rodgers C, Davies JF, Bayman E, Smeal T, Maegley KA, Gehring MR.
    Bioorg Med Chem Lett; 2008 Dec 01; 18(23):6273-8. PubMed ID: 18929486
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  • 3. Novel, potent small-molecule inhibitors of the molecular chaperone Hsp90 discovered through structure-based design.
    Dymock BW, Barril X, Brough PA, Cansfield JE, Massey A, McDonald E, Hubbard RE, Surgenor A, Roughley SD, Webb P, Workman P, Wright L, Drysdale MJ.
    J Med Chem; 2005 Jun 30; 48(13):4212-5. PubMed ID: 15974572
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  • 8. Discovery and design of novel HSP90 inhibitors using multiple fragment-based design strategies.
    Huth JR, Park C, Petros AM, Kunzer AR, Wendt MD, Wang X, Lynch CL, Mack JC, Swift KM, Judge RA, Chen J, Richardson PL, Jin S, Tahir SK, Matayoshi ED, Dorwin SA, Ladror US, Severin JM, Walter KA, Bartley DM, Fesik SW, Elmore SW, Hajduk PJ.
    Chem Biol Drug Des; 2007 Jul 30; 70(1):1-12. PubMed ID: 17630989
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  • 9. Fragment-based discovery of hydroxy-indazole-carboxamides as novel small molecule inhibitors of Hsp90.
    Buchstaller HP, Eggenweiler HM, Sirrenberg C, Grädler U, Musil D, Hoppe E, Zimmermann A, Schwartz H, März J, Bomke J, Wegener A, Wolf M.
    Bioorg Med Chem Lett; 2012 Jul 01; 22(13):4396-403. PubMed ID: 22632933
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  • 13. Inside the Hsp90 inhibitors binding mode through induced fit docking.
    Lauria A, Ippolito M, Almerico AM.
    J Mol Graph Model; 2009 Feb 01; 27(6):712-22. PubMed ID: 19084447
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  • 14. In vitro biological characterization of a novel, synthetic diaryl pyrazole resorcinol class of heat shock protein 90 inhibitors.
    Sharp SY, Boxall K, Rowlands M, Prodromou C, Roe SM, Maloney A, Powers M, Clarke PA, Box G, Sanderson S, Patterson L, Matthews TP, Cheung KM, Ball K, Hayes A, Raynaud F, Marais R, Pearl L, Eccles S, Aherne W, McDonald E, Workman P.
    Cancer Res; 2007 Mar 01; 67(5):2206-16. PubMed ID: 17332351
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  • 15. Discovery and development of pyrazole-scaffold Hsp90 inhibitors.
    McDonald E, Jones K, Brough PA, Drysdale MJ, Workman P.
    Curr Top Med Chem; 2006 Mar 01; 6(11):1193-203. PubMed ID: 16842156
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  • 17. Molecular modelling and docking studies on heat shock protein 90 (Hsp90) inhibitors.
    Saxena AK, Saxena S, Chaudhaery SS.
    SAR QSAR Environ Res; 2010 Jan 01; 21(1):1-20. PubMed ID: 20373211
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  • 19. N-(3-(phenylcarbamoyl)arylpyrimidine)-5-carboxamides as potent and selective inhibitors of Lck: structure, synthesis and SAR.
    Deak HL, Newcomb JR, Nunes JJ, Boucher C, Cheng AC, DiMauro EF, Epstein LF, Gallant P, Hodous BL, Huang X, Lee JH, Patel VF, Schneider S, Turci SM, Zhu X.
    Bioorg Med Chem Lett; 2008 Feb 01; 18(3):1172-6. PubMed ID: 18083554
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