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Journal Abstract Search

155 related items for PubMed ID: 16218577

  • 1. Enzyme redesign: two mutations cooperate to convert cycloartenol synthase into an accurate lanosterol synthase.
    Lodeiro S, Schulz-Gasch T, Matsuda SP.
    J Am Chem Soc; 2005 Oct 19; 127(41):14132-3. PubMed ID: 16218577
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  • 5. Mechanistic insights into oxidosqualene cyclizations through homology modeling.
    Schulz-Gasch T, Stahl M.
    J Comput Chem; 2003 Apr 30; 24(6):741-53. PubMed ID: 12666166
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  • 6. Protein engineering of Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase into parkeol synthase.
    Liu YT, Hu TC, Chang CH, Shie WS, Wu TK.
    Org Lett; 2012 Oct 19; 14(20):5222-5. PubMed ID: 23043506
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  • 7. Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase.
    Thoma R, Schulz-Gasch T, D'Arcy B, Benz J, Aebi J, Dehmlow H, Hennig M, Stihle M, Ruf A.
    Nature; 2004 Nov 04; 432(7013):118-22. PubMed ID: 15525992
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  • 9. Catalytic mechanism and product specificity of oxidosqualene-lanosterol cyclase: a QM/MM study.
    Tian BX, Eriksson LA.
    J Phys Chem B; 2012 Nov 29; 116(47):13857-62. PubMed ID: 23130825
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  • 10. Directed evolution to generate cycloartenol synthase mutants that produce lanosterol.
    Meyer MM, Xu R, Matsuda SP.
    Org Lett; 2002 Apr 18; 4(8):1395-8. PubMed ID: 11950371
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  • 11. Lanosterol synthase in dicotyledonous plants.
    Suzuki M, Xiang T, Ohyama K, Seki H, Saito K, Muranaka T, Hayashi H, Katsube Y, Kushiro T, Shibuya M, Ebizuka Y.
    Plant Cell Physiol; 2006 May 18; 47(5):565-71. PubMed ID: 16531458
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  • 13. A putative precursor of isomalabaricane triterpenoids from lanosterol synthase mutants.
    Lodeiro S, Wilson WK, Shan H, Matsuda SP.
    Org Lett; 2006 Feb 02; 8(3):439-42. PubMed ID: 16435854
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  • 14. Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase: a chemistry-biology interdisciplinary study of the protein's structure-function-reaction mechanism relationships.
    Wu TK, Chang CH, Liu YT, Wang TT.
    Chem Rec; 2008 Feb 02; 8(5):302-25. PubMed ID: 18956480
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  • 15. Oryza sativa Parkeol Cyclase: Changes in the Substrate-Folding Conformation and the Deprotonation Sites on Mutation at Tyr257: Importance of the Hydroxy Group and Steric Bulk.
    Suzuki A, Aikawa Y, Ito R, Hoshino T.
    Chembiochem; 2019 Nov 18; 20(22):2862-2875. PubMed ID: 31180162
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  • 16. Tryptophan 232 within oxidosqualene-lanosterol cyclase from Saccharomyces cerevisiae influences rearrangement and deprotonation but not cyclization reactions.
    Wu TK, Yu MT, Liu YT, Chang CH, Wang HJ, Diau EW.
    Org Lett; 2006 Mar 30; 8(7):1319-22. PubMed ID: 16562881
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  • 17. Protostadienol synthase from Aspergillus fumigatus: functional conversion into lanosterol synthase.
    Kimura M, Kushiro T, Shibuya M, Ebizuka Y, Abe I.
    Biochem Biophys Res Commun; 2010 Jan 01; 391(1):899-902. PubMed ID: 19951700
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  • 18. Plant oxidosqualene metabolism: cycloartenol synthase-dependent sterol biosynthesis in Nicotiana benthamiana.
    Gas-Pascual E, Berna A, Bach TJ, Schaller H.
    PLoS One; 2014 Jan 01; 9(10):e109156. PubMed ID: 25343375
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  • 19. Phenylalanine 445 within oxidosqualene-lanosterol cyclase from Saccharomyces cerevisiae influences C-Ring cyclization and deprotonation reactions.
    Wu TK, Liu YT, Chiu FH, Chang CH.
    Org Lett; 2006 Oct 12; 8(21):4691-4. PubMed ID: 17020279
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  • 20. Site-saturated mutagenesis of histidine 234 of Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase demonstrates dual functions in cyclization and rearrangement reactions.
    Wu TK, Liu YT, Chang CH, Yu MT, Wang HJ.
    J Am Chem Soc; 2006 May 17; 128(19):6414-9. PubMed ID: 16683806
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