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Journal Abstract Search

387 related items for PubMed ID: 16218994

  • 1. Development of highly potent and selective dynorphin A analogues as new medicines.
    Lung FD, Chen CH, Liu JH.
    J Pept Res; 2005 Nov; 66(5):263-76. PubMed ID: 16218994
    [Abstract] [Full Text] [Related]

  • 2. Design, synthesis, and biological activities of cyclic lactam peptide analogues of dynorphine A(1-11)-NH2.
    Lung FD, Collins N, Stropova D, Davis P, Yamamura HI, Porreca F, Hruby VJ.
    J Med Chem; 1996 Mar 01; 39(5):1136-41. PubMed ID: 8676350
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  • 3. Synthesis and opioid activity of conformationally constrained dynorphin A analogues. 2. Conformational constraint in the "address" sequence.
    Arttamangkul S, Ishmael JE, Murray TF, Grandy DK, DeLander GE, Kieffer BL, Aldrich JV.
    J Med Chem; 1997 Apr 11; 40(8):1211-8. PubMed ID: 9111295
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  • 4. Design, synthesis, and biological properties of highly potent cyclic dynorphin A analogues. Analogues cyclized between positions 5 and 11.
    Meyer JP, Collins N, Lung FD, Davis P, Zalewska T, Porreca F, Yamamura HI, Hruby VJ.
    J Med Chem; 1994 Nov 11; 37(23):3910-7. PubMed ID: 7966152
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and opioid activity of side-chain-to-side-chain cyclic dynorphin A-(1-11) amide analogues cyclized between positions 2 and 5. 1. Substitutions in position 3.
    Vig BS, Murray TF, Aldrich JV.
    J Med Chem; 2004 Jan 15; 47(2):446-55. PubMed ID: 14711314
    [Abstract] [Full Text] [Related]

  • 6. Effects of the substitution of Phe4 in the opioid peptide [D-Ala8]dynorphin A-(1-11)NH2.
    Vig BS, Zheng MQ, Murray TF, Aldrich JV.
    J Med Chem; 2003 Sep 11; 46(19):4002-8. PubMed ID: 12954053
    [Abstract] [Full Text] [Related]

  • 7. Structure-activity relationships of arodyn, a novel acetylated kappa opioid receptor antagonist.
    Bennett MA, Murray TF, Aldrich JV.
    J Pept Res; 2005 Mar 11; 65(3):322-32. PubMed ID: 15787962
    [Abstract] [Full Text] [Related]

  • 8. Dynorphin A analogs containing a conformationally constrained phenylalanine derivative in position 4: reversal of preferred stereochemistry for opioid receptor affinity and discrimination of kappa vs. delta receptors.
    Aldrich JV, Zheng QI, Murray TF.
    Chirality; 2001 Mar 11; 13(3):125-9. PubMed ID: 11270320
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and opioid activity of [D-Pro10]dynorphin A-(1-11) analogues with N-terminal alkyl substitution.
    Choi H, Murray TF, DeLander GE, Schmidt WK, Aldrich JV.
    J Med Chem; 1997 Aug 15; 40(17):2733-9. PubMed ID: 9276018
    [Abstract] [Full Text] [Related]

  • 10. Design and synthesis of highly potent and selective cyclic dynorphin A analogues.
    Kawasaki AM, Knapp RJ, Kramer TH, Wire WS, Vasquez OS, Yamamura HI, Burks TF, Hruby VJ.
    J Med Chem; 1990 Jul 15; 33(7):1874-9. PubMed ID: 1972964
    [Abstract] [Full Text] [Related]

  • 11. De novo design, synthesis, and biological activities of high-affinity and selective non-peptide agonists of the delta-opioid receptor.
    Liao S, Alfaro-Lopez J, Shenderovich MD, Hosohata K, Lin J, Li X, Stropova D, Davis P, Jernigan KA, Porreca F, Yamamura HI, Hruby VJ.
    J Med Chem; 1998 Nov 19; 41(24):4767-76. PubMed ID: 9822547
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  • 15. [2',6'-Dimethyltyrosine]dynorphin A(1-11)-NH2 analogues lacking an N-terminal amino group: potent and selective kappa opioid antagonists.
    Lu Y, Nguyen TM, Weltrowska G, Berezowska I, Lemieux C, Chung NN, Schiller PW.
    J Med Chem; 2001 Sep 13; 44(19):3048-53. PubMed ID: 11543672
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  • 20. Prediction of the conformational requirements for binding to the kappa-opioid receptor and its subtypes. I. Novel alpha-helical cyclic peptides and their role in receptor selectivity.
    Collins N, Hruby VJ.
    Biopolymers; 1994 Sep 13; 34(9):1231-41. PubMed ID: 7948735
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