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146 related items for PubMed ID: 16219767

  • 1. Cooperative dimerization of fibroblast growth factor 1 (FGF1) upon a single heparin saccharide may drive the formation of 2:2:1 FGF1.FGFR2c.heparin ternary complexes.
    Robinson CJ, Harmer NJ, Goodger SJ, Blundell TL, Gallagher JT.
    J Biol Chem; 2005 Dec 23; 280(51):42274-82. PubMed ID: 16219767
    [Abstract] [Full Text] [Related]

  • 2. Multimers of the fibroblast growth factor (FGF)-FGF receptor-saccharide complex are formed on long oligomers of heparin.
    Harmer NJ, Robinson CJ, Adam LE, Ilag LL, Robinson CV, Gallagher JT, Blundell TL.
    Biochem J; 2006 Feb 01; 393(Pt 3):741-8. PubMed ID: 16223363
    [Abstract] [Full Text] [Related]

  • 3. Control of fibroblast growth factor (FGF) 7- and FGF1-induced mitogenesis and downstream signaling by distinct heparin octasaccharide motifs.
    Luo Y, Ye S, Kan M, McKeehan WL.
    J Biol Chem; 2006 Jul 28; 281(30):21052-21061. PubMed ID: 16728399
    [Abstract] [Full Text] [Related]

  • 4. Cooperative heparin-mediated oligomerization of fibroblast growth factor-1 (FGF1) precedes recruitment of FGFR2 to ternary complexes.
    Brown A, Robinson CJ, Gallagher JT, Blundell TL.
    Biophys J; 2013 Apr 16; 104(8):1720-30. PubMed ID: 23601319
    [Abstract] [Full Text] [Related]

  • 5. Minimal heparin/heparan sulfate sequences for binding to fibroblast growth factor-1.
    Guerrini M, Agulles T, Bisio A, Hricovini M, Lay L, Naggi A, Poletti L, Sturiale L, Torri G, Casu B.
    Biochem Biophys Res Commun; 2002 Mar 22; 292(1):222-30. PubMed ID: 11890696
    [Abstract] [Full Text] [Related]

  • 6. Heparin modulates the mitogenic activity of fibroblast growth factor by inducing dimerization of its receptor. a 3D view by using NMR.
    Nieto L, Canales Á, Fernández IS, Santillana E, González-Corrochano R, Redondo-Horcajo M, Cañada FJ, Nieto P, Martín-Lomas M, Giménez-Gallego G, Jiménez-Barbero J.
    Chembiochem; 2013 Sep 23; 14(14):1732-44. PubMed ID: 23940086
    [Abstract] [Full Text] [Related]

  • 7. Differential effects of heparin saccharides on the formation of specific fibroblast growth factor (FGF) and FGF receptor complexes.
    Ostrovsky O, Berman B, Gallagher J, Mulloy B, Fernig DG, Delehedde M, Ron D.
    J Biol Chem; 2002 Jan 25; 277(4):2444-53. PubMed ID: 11714710
    [Abstract] [Full Text] [Related]

  • 8. Heparan sulfate-related oligosaccharides in ternary complex formation with fibroblast growth factors 1 and 2 and their receptors.
    Jastrebova N, Vanwildemeersch M, Rapraeger AC, Giménez-Gallego G, Lindahl U, Spillmann D.
    J Biol Chem; 2006 Sep 15; 281(37):26884-92. PubMed ID: 16807244
    [Abstract] [Full Text] [Related]

  • 9. Influence of heparin mimetics on assembly of the FGF.FGFR4 signaling complex.
    Saxena K, Schieborr U, Anderka O, Duchardt-Ferner E, Elshorst B, Gande SL, Janzon J, Kudlinzki D, Sreeramulu S, Dreyer MK, Wendt KU, Herbert C, Duchaussoy P, Bianciotto M, Driguez PA, Lassalle G, Savi P, Mohammadi M, Bono F, Schwalbe H.
    J Biol Chem; 2010 Aug 20; 285(34):26628-40. PubMed ID: 20547770
    [Abstract] [Full Text] [Related]

  • 10. Activating and inhibitory heparin sequences for FGF-2 (basic FGF). Distinct requirements for FGF-1, FGF-2, and FGF-4.
    Guimond S, Maccarana M, Olwin BB, Lindahl U, Rapraeger AC.
    J Biol Chem; 1993 Nov 15; 268(32):23906-14. PubMed ID: 7693696
    [Abstract] [Full Text] [Related]

  • 11. Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin.
    Pellegrini L, Burke DF, von Delft F, Mulloy B, Blundell TL.
    Nature; 2000 Oct 26; 407(6807):1029-34. PubMed ID: 11069186
    [Abstract] [Full Text] [Related]

  • 12. Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuity.
    Olsen SK, Ibrahimi OA, Raucci A, Zhang F, Eliseenkova AV, Yayon A, Basilico C, Linhardt RJ, Schlessinger J, Mohammadi M.
    Proc Natl Acad Sci U S A; 2004 Jan 27; 101(4):935-40. PubMed ID: 14732692
    [Abstract] [Full Text] [Related]

  • 13. Dimerization effect of sucrose octasulfate on rat FGF1.
    Kulahin N, Kiselyov V, Kochoyan A, Kristensen O, Kastrup JS, Berezin V, Bock E, Gajhede M.
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2008 Jun 01; 64(Pt 6):448-52. PubMed ID: 18540049
    [Abstract] [Full Text] [Related]

  • 14. Solution NMR structure of a human FGF-1 monomer, activated by a hexasaccharide heparin-analogue.
    Canales A, Lozano R, López-Méndez B, Angulo J, Ojeda R, Nieto PM, Martín-Lomas M, Giménez-Gallego G, Jiménez-Barbero J.
    FEBS J; 2006 Oct 01; 273(20):4716-27. PubMed ID: 16995857
    [Abstract] [Full Text] [Related]

  • 15. Gas-Phase Analysis of the Complex of Fibroblast GrowthFactor 1 with Heparan Sulfate: A Traveling Wave Ion Mobility Spectrometry (TWIMS) and Molecular Modeling Study.
    Zhao Y, Singh A, Xu Y, Zong C, Zhang F, Boons GJ, Liu J, Linhardt RJ, Woods RJ, Amster IJ.
    J Am Soc Mass Spectrom; 2017 Jan 01; 28(1):96-109. PubMed ID: 27663556
    [Abstract] [Full Text] [Related]

  • 16. Similarities and differences between the effects of heparin and glypican-1 on the bioactivity of acidic fibroblast growth factor and the keratinocyte growth factor.
    Berman B, Ostrovsky O, Shlissel M, Lang T, Regan D, Vlodavsky I, Ishai-Michaeli R, Ron D.
    J Biol Chem; 1999 Dec 17; 274(51):36132-8. PubMed ID: 10593896
    [Abstract] [Full Text] [Related]

  • 17. Binding of heparin/heparan sulfate to fibroblast growth factor receptor 4.
    Loo BM, Kreuger J, Jalkanen M, Lindahl U, Salmivirta M.
    J Biol Chem; 2001 May 18; 276(20):16868-76. PubMed ID: 11278860
    [Abstract] [Full Text] [Related]

  • 18. Biosynthetic oligosaccharide libraries for identification of protein-binding heparan sulfate motifs. Exploring the structural diversity by screening for fibroblast growth factor (FGF)1 and FGF2 binding.
    Jemth P, Kreuger J, Kusche-Gullberg M, Sturiale L, Giménez-Gallego G, Lindahl U.
    J Biol Chem; 2002 Aug 23; 277(34):30567-73. PubMed ID: 12058038
    [Abstract] [Full Text] [Related]

  • 19. Uncoupling the Mitogenic and Metabolic Functions of FGF1 by Tuning FGF1-FGF Receptor Dimer Stability.
    Huang Z, Tan Y, Gu J, Liu Y, Song L, Niu J, Zhao L, Srinivasan L, Lin Q, Deng J, Li Y, Conklin DJ, Neubert TA, Cai L, Li X, Mohammadi M.
    Cell Rep; 2017 Aug 15; 20(7):1717-1728. PubMed ID: 28813681
    [Abstract] [Full Text] [Related]

  • 20. FGF2-Heparin co-crystal complex-assisted design of mutants FGF1 and FGF7 with predictable heparin affinities.
    Wong P, Burgess WH.
    J Biol Chem; 1998 Jul 17; 273(29):18617-22. PubMed ID: 9660835
    [Abstract] [Full Text] [Related]


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