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Journal Abstract Search

217 related items for PubMed ID: 16220066

  • 1. Aortic smooth muscle relaxants KMUP-3 and KMUP-4, two nitrophenylpiperazine derivatives of xanthine, display cGMP-enhancing activity: roles of endothelium, phosphodiesterase, and K+ channel.
    Wu BN, Chen IC, Lin RJ, Chiu CC, An LM, Chen IJ.
    J Cardiovasc Pharmacol; 2005 Nov; 46(5):600-8. PubMed ID: 16220066
    [Abstract] [Full Text] [Related]

  • 2. A xanthine-based KMUP-1 with cyclic GMP enhancing and K(+) channels opening activities in rat aortic smooth muscle.
    Wu BN, Lin RJ, Lin CY, Shen KP, Chiang LC, Chen IJ.
    Br J Pharmacol; 2001 Sep; 134(2):265-74. PubMed ID: 11564644
    [Abstract] [Full Text] [Related]

  • 3. KMUP-1 relaxes rabbit corpus cavernosum smooth muscle in vitro and in vivo: involvement of cyclic GMP and K(+) channels.
    Lin RJ, Wu BN, Lo YC, Shen KP, Lin YT, Huang CH, Chen IJ.
    Br J Pharmacol; 2002 Mar; 135(5):1159-66. PubMed ID: 11877322
    [Abstract] [Full Text] [Related]

  • 4. KMUP-1, a xanthine derivative, induces relaxation of guinea-pig isolated trachea: the role of the epithelium, cyclic nucleotides and K+ channels.
    Wu BN, Lin RJ, Lo YC, Shen KP, Wang CC, Lin YT, Chen IJ.
    Br J Pharmacol; 2004 Aug; 142(7):1105-14. PubMed ID: 15237094
    [Abstract] [Full Text] [Related]

  • 5. A xanthine-based epithelium-dependent airway relaxant KMUP-3 (7-[2-[4-(4-nitrobenzene)piperazinyl]ethyl]-1,3-dimethylxanthine) increases respiratory performance and protects against tumor necrosis factor-alpha-induced tracheal contraction, involving nitric oxide release and expression of cGMP and protein kinase G.
    Lin RJ, Wu BN, Lo YC, An LM, Dai ZK, Lin YT, Tang CS, Chen IJ.
    J Pharmacol Exp Ther; 2006 Feb; 316(2):709-17. PubMed ID: 16234412
    [Abstract] [Full Text] [Related]

  • 6. Endothelium-dependent and -independent vasorelaxation by a theophylline derivative MCPT: roles of cyclic nucleotides, potassium channel opening and phosphodiesterase inhibition.
    Lo YC, Tsou HH, Lin RJ, Wu DC, Wu BN, Lin YT, Chen IJ.
    Life Sci; 2005 Jan 07; 76(8):931-44. PubMed ID: 15589969
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of proinflammatory tumor necrosis factor-{alpha}-induced inducible nitric-oxide synthase by xanthine-based 7-[2-[4-(2-chlorobenzene)piperazinyl]ethyl]-1,3-dimethylxanthine (KMUP-1) and 7-[2-[4-(4-nitrobenzene)piperazinyl]ethyl]-1, 3-dimethylxanthine (KMUP-3) in rat trachea: The involvement of soluble guanylate cyclase and protein kinase G.
    Wu BN, Chen CW, Liou SF, Yeh JL, Chung HH, Chen IJ.
    Mol Pharmacol; 2006 Sep 07; 70(3):977-85. PubMed ID: 16754782
    [Abstract] [Full Text] [Related]

  • 8. Endothelium-dependent relaxation of rat aorta by butein, a novel cyclic AMP-specific phosphodiesterase inhibitor.
    Yu SM, Cheng ZJ, Kuo SC.
    Eur J Pharmacol; 1995 Jun 23; 280(1):69-77. PubMed ID: 7498256
    [Abstract] [Full Text] [Related]

  • 9. Endothelium-dependent and independent relaxation of the rat aorta by cyclic nucleotide phosphodiesterase inhibitors.
    Komas N, Lugnier C, Stoclet JC.
    Br J Pharmacol; 1991 Oct 23; 104(2):495-503. PubMed ID: 1665741
    [Abstract] [Full Text] [Related]

  • 10. KMUP-1 activates BKCa channels in basilar artery myocytes via cyclic nucleotide-dependent protein kinases.
    Wu BN, Tu HF, Welsh DG, Chen IJ.
    Br J Pharmacol; 2005 Nov 23; 146(6):862-71. PubMed ID: 16151435
    [Abstract] [Full Text] [Related]

  • 11. Effects of cyclic GMP elevation on isoprenaline-induced increase in cyclic AMP and relaxation in rat aortic smooth muscle: role of phosphodiesterase 3.
    Delpy E, Coste H, Gouville AC.
    Br J Pharmacol; 1996 Oct 23; 119(3):471-8. PubMed ID: 8894166
    [Abstract] [Full Text] [Related]

  • 12. The xanthine derivative KMUP-1 inhibits models of pulmonary artery hypertension via increased NO and cGMP-dependent inhibition of RhoA/Rho kinase.
    Chung HH, Dai ZK, Wu BN, Yeh JL, Chai CY, Chu KS, Liu CP, Chen IJ.
    Br J Pharmacol; 2010 Jun 23; 160(4):971-86. PubMed ID: 20590592
    [Abstract] [Full Text] [Related]

  • 13. Contribution of K+ channels and ouabain-sensitive mechanisms to the endothelium-dependent relaxations of horse penile small arteries.
    Prieto D, Simonsen U, Hernández M, García-Sacristán A.
    Br J Pharmacol; 1998 Apr 23; 123(8):1609-20. PubMed ID: 9605568
    [Abstract] [Full Text] [Related]

  • 14. Vasorelaxant effect of isoliquiritigenin, a novel soluble guanylate cyclase activator, in rat aorta.
    Yu SM, Kuo SC.
    Br J Pharmacol; 1995 Apr 23; 114(8):1587-94. PubMed ID: 7599926
    [Abstract] [Full Text] [Related]

  • 15. Evidence that potassium channels make a major contribution to SIN-1-evoked relaxation of rat isolated mesenteric artery.
    Plane F, Hurrell A, Jeremy JY, Garland CJ.
    Br J Pharmacol; 1996 Dec 23; 119(8):1557-62. PubMed ID: 8982501
    [Abstract] [Full Text] [Related]

  • 16. The role of NO-cGMP pathway and potassium channels on the relaxation induced by clonidine in the rat mesenteric arterial bed.
    Pimentel AM, Costa CA, Carvalho LC, Brandão RM, Rangel BM, Tano T, Soares de Moura R, Resende AC.
    Vascul Pharmacol; 2007 May 23; 46(5):353-9. PubMed ID: 17258511
    [Abstract] [Full Text] [Related]

  • 17. The anti-diabetic drug repaglinide induces vasorelaxation via activation of PKA and PKG in aortic smooth muscle.
    Kim HW, Li H, Kim HS, Shin SE, Jung WK, Ha KS, Han ET, Hong SH, Choi IW, Firth AL, Bang H, Park WS.
    Vascul Pharmacol; 2016 Sep 23; 84():38-46. PubMed ID: 27435474
    [Abstract] [Full Text] [Related]

  • 18. Role of phosphodiesterases III and IV in the modulation of vascular cyclic AMP content by the NO/cyclic GMP pathway.
    Eckly AE, Lugnier C.
    Br J Pharmacol; 1994 Oct 23; 113(2):445-50. PubMed ID: 7834194
    [Abstract] [Full Text] [Related]

  • 19. Labedipinedilol-C: a third-generation dihydropyridine-type calcium channel antagonist displaying K+ channel opening, NO-dependent and adrenergic antagonist activities.
    Yeh JL, Liou SF, Liang JC, Lee CH, Chiu CC, Lin YT, Chen IJ.
    J Cardiovasc Pharmacol; 2005 Aug 23; 46(2):130-40. PubMed ID: 16044023
    [Abstract] [Full Text] [Related]

  • 20. Roles of calcium-activated and voltage-gated delayed rectifier potassium channels in endothelium-dependent vasorelaxation of the rabbit middle cerebral artery.
    Dong H, Waldron GJ, Cole WC, Triggle CR.
    Br J Pharmacol; 1998 Mar 23; 123(5):821-32. PubMed ID: 9535009
    [Abstract] [Full Text] [Related]

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