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158 related items for PubMed ID: 16221533
21. Effects of aripiprazole and its active metabolite dehydroaripiprazole on the activities of drug efflux transporters expressed both in the intestine and at the blood-brain barrier. Nagasaka Y, Oda K, Iwatsubo T, Kawamura A, Usui T. Biopharm Drug Dispos; 2012 Sep; 33(6):304-15. PubMed ID: 22847220 [Abstract] [Full Text] [Related]
22. Improvement of the oral drug absorption of topotecan through the inhibition of intestinal xenobiotic efflux transporter, breast cancer resistance protein, by excipients. Yamagata T, Kusuhara H, Morishita M, Takayama K, Benameur H, Sugiyama Y. Drug Metab Dispos; 2007 Jul; 35(7):1142-8. PubMed ID: 17446265 [Abstract] [Full Text] [Related]
23. Interplay between MRP inhibition and metabolism of MRP inhibitors: the case of curcumin. Wortelboer HM, Usta M, van der Velde AE, Boersma MG, Spenkelink B, van Zanden JJ, Rietjens IM, van Bladeren PJ, Cnubben NH. Chem Res Toxicol; 2003 Dec; 16(12):1642-51. PubMed ID: 14680379 [Abstract] [Full Text] [Related]
24. Zinc finger nuclease-mediated gene knockout results in loss of transport activity for P-glycoprotein, BCRP, and MRP2 in Caco-2 cells. Sampson KE, Brinker A, Pratt J, Venkatraman N, Xiao Y, Blasberg J, Steiner T, Bourner M, Thompson DC. Drug Metab Dispos; 2015 Feb; 43(2):199-207. PubMed ID: 25388687 [Abstract] [Full Text] [Related]
25. 5-Fluorouracil treatment alters the expression of intestinal transporters in rats. Yotsumoto K, Akiyoshi T, Wada N, Imaoka A, Ohtani H. Biopharm Drug Dispos; 2017 Dec; 38(9):509-516. PubMed ID: 28849584 [Abstract] [Full Text] [Related]
26. Closing the gaps: a full scan of the intestinal expression of p-glycoprotein, breast cancer resistance protein, and multidrug resistance-associated protein 2 in male and female rats. MacLean C, Moenning U, Reichel A, Fricker G. Drug Metab Dispos; 2008 Jul; 36(7):1249-54. PubMed ID: 18378562 [Abstract] [Full Text] [Related]
27. Role of ATP-binding cassette drug transporters in the intestinal absorption of tanshinone IIB, one of the major active diterpenoids from the root of Salvia miltiorrhiza. Yu XY, Zhou ZW, Lin SG, Chen X, Yu XQ, Liang J, Duan W, Wen JY, Li XT, Zhou SF. Xenobiotica; 2007 Apr; 37(4):375-415. PubMed ID: 17455112 [Abstract] [Full Text] [Related]
28. Expression and function of efflux drug transporters in the intestine. Takano M, Yumoto R, Murakami T. Pharmacol Ther; 2006 Jan; 109(1-2):137-61. PubMed ID: 16209890 [Abstract] [Full Text] [Related]
29. Characterization of efflux transport of the PDE5 inhibitors, vardenafil and sildenafil. Choi MK, Song IS. J Pharm Pharmacol; 2012 Aug; 64(8):1074-83. PubMed ID: 22775210 [Abstract] [Full Text] [Related]
30. Development and characterization of LLC-PK1 cells containing Sprague-Dawley rat Abcb1a (Mdr1a): comparison of rat P-glycoprotein transport to human and mouse. Booth-Genthe CL, Louie SW, Carlini EJ, Li B, Leake BF, Eisenhandler R, Hochman JH, Mei Q, Kim RB, Rushmore TH, Yamazaki M. J Pharmacol Toxicol Methods; 2006 Aug; 54(1):78-89. PubMed ID: 16545584 [Abstract] [Full Text] [Related]
31. High-activity p-glycoprotein, multidrug resistance protein 2, and breast cancer resistance protein membrane vesicles prepared from transiently transfected human embryonic kidney 293-epstein-barr virus nuclear antigen cells. Karlsson JE, Heddle C, Rozkov A, Rotticci-Mulder J, Tuvesson O, Hilgendorf C, Andersson TB. Drug Metab Dispos; 2010 Apr; 38(4):705-14. PubMed ID: 20071452 [Abstract] [Full Text] [Related]
32. Evidence of Oatp and Mdr1 in cryopreserved rat hepatocytes. Jørgensen L, Van Beek J, Lund S, Schousboe A, Badolo L. Eur J Pharm Sci; 2007 Feb; 30(2):181-9. PubMed ID: 17174077 [Abstract] [Full Text] [Related]
33. P-glycoprotein (MDR1/ABCB1) and breast cancer resistance protein (BCRP/ABCG2) restrict brain accumulation of the JAK1/2 inhibitor, CYT387. Durmus S, Xu N, Sparidans RW, Wagenaar E, Beijnen JH, Schinkel AH. Pharmacol Res; 2013 Oct; 76():9-16. PubMed ID: 23827160 [Abstract] [Full Text] [Related]
34. Modulation of mdr1a and CYP3A gene expression in the intestine and liver as possible cause of changes in the cyclosporin A disposition kinetics by dexamethasone. Yokogawa K, Shimada T, Higashi Y, Itoh Y, Masue T, Ishizaki J, Asahi M, Miyamoto K. Biochem Pharmacol; 2002 Feb 15; 63(4):777-83. PubMed ID: 11992648 [Abstract] [Full Text] [Related]
35. Interaction Studies of Resolvin E1 Analog (RX-10045) with Efflux Transporters. Cholkar K, Trinh HM, Vadlapudi AD, Wang Z, Pal D, Mitra AK. J Ocul Pharmacol Ther; 2015 May 15; 31(4):248-55. PubMed ID: 25844889 [Abstract] [Full Text] [Related]
37. The effect of rifampin treatment on intestinal expression of human MRP transporters. Fromm MF, Kauffmann HM, Fritz P, Burk O, Kroemer HK, Warzok RW, Eichelbaum M, Siegmund W, Schrenk D. Am J Pathol; 2000 Nov 15; 157(5):1575-80. PubMed ID: 11073816 [Abstract] [Full Text] [Related]
38. Morphological and functional changes in p-glycoprotein during dexamethasone-induced hepatomegaly. Micuda S, Fuksa L, Mundlova L, Osterreicher J, Mokry J, Cermanova J, Brcakova E, Staud F, Pokorna P, Martinkova J. Clin Exp Pharmacol Physiol; 2007 Apr 15; 34(4):296-303. PubMed ID: 17324141 [Abstract] [Full Text] [Related]