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329 related items for PubMed ID: 16222339

  • 1. The translesion DNA polymerase theta plays a dominant role in immunoglobulin gene somatic hypermutation.
    Zan H, Shima N, Xu Z, Al-Qahtani A, Evinger Iii AJ, Zhong Y, Schimenti JC, Casali P.
    EMBO J; 2005 Nov 02; 24(21):3757-69. PubMed ID: 16222339
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  • 2. DNA polymerases β and λ do not directly affect Ig variable region somatic hypermutation although their absence reduces the frequency of mutations.
    Schrader CE, Linehan EK, Ucher AJ, Bertocci B, Stavnezer J.
    DNA Repair (Amst); 2013 Dec 02; 12(12):1087-93. PubMed ID: 24084171
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  • 3. Biased dA/dT somatic hypermutation as regulated by the heavy chain intronic iEmu enhancer and 3'Ealpha enhancers in human lymphoblastoid B cells.
    Komori A, Xu Z, Wu X, Zan H, Casali P.
    Mol Immunol; 2006 Apr 02; 43(11):1817-26. PubMed ID: 16412510
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  • 4. DNA polymerase theta contributes to the generation of C/G mutations during somatic hypermutation of Ig genes.
    Masuda K, Ouchida R, Takeuchi A, Saito T, Koseki H, Kawamura K, Tagawa M, Tokuhisa T, Azuma T, O-Wang J.
    Proc Natl Acad Sci U S A; 2005 Sep 27; 102(39):13986-91. PubMed ID: 16172387
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  • 5. The translesion DNA polymerase zeta plays a major role in Ig and bcl-6 somatic hypermutation.
    Zan H, Komori A, Li Z, Cerutti A, Schaffer A, Flajnik MF, Diaz M, Casali P.
    Immunity; 2001 May 27; 14(5):643-53. PubMed ID: 11371365
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  • 6. Intricate targeting of immunoglobulin somatic hypermutation maximizes the efficiency of affinity maturation.
    Zheng NY, Wilson K, Jared M, Wilson PC.
    J Exp Med; 2005 May 02; 201(9):1467-78. PubMed ID: 15867095
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  • 7. Lupus-prone MRL/faslpr/lpr mice display increased AID expression and extensive DNA lesions, comprising deletions and insertions, in the immunoglobulin locus: concurrent upregulation of somatic hypermutation and class switch DNA recombination.
    Zan H, Zhang J, Ardeshna S, Xu Z, Park SR, Casali P.
    Autoimmunity; 2009 Feb 02; 42(2):89-103. PubMed ID: 19156553
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  • 10. Strand-biased spreading of mutations during somatic hypermutation.
    Unniraman S, Schatz DG.
    Science; 2007 Aug 31; 317(5842):1227-30. PubMed ID: 17761884
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  • 14. Integrity of immunoglobulin variable regions is supported by GANP during AID-induced somatic hypermutation in germinal center B cells.
    Eid MMA, Shimoda M, Singh SK, Almofty SA, Pham P, Goodman MF, Maeda K, Sakaguchi N.
    Int Immunol; 2017 May 01; 29(5):211-220. PubMed ID: 28541550
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  • 17. Analysis of Ig gene hypermutation in Ung(-/-)Polh(-/-) mice suggests that UNG and A:T mutagenesis pathway target different U:G lesions.
    Li S, Zhao Y, Wang JY.
    Mol Immunol; 2013 Mar 01; 53(3):214-7. PubMed ID: 22960197
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