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Journal Abstract Search

782 related items for PubMed ID: 16222725

  • 1. Enantiomeric 1,2,4-trioxanes display equivalent in vitro antimalarial activity versus Plasmodium falciparum malaria parasites: implications for the molecular mechanism of action of the artemisinins.
    O'Neill PM, Rawe SL, Borstnik K, Miller A, Ward SA, Bray PG, Davies J, Oh CH, Posner GH.
    Chembiochem; 2005 Nov; 6(11):2048-54. PubMed ID: 16222725
    [Abstract] [Full Text] [Related]

  • 2. Novel bis- and tris-1,2,4-trioxanes: synthesis and antimalarial activity against multidrug-resistant Plasmodium yoelii in Swiss mice.
    Singh C, Verma VP, Naikade NK, Singh AS, Hassam M, Puri SK.
    J Med Chem; 2008 Dec 11; 51(23):7581-92. PubMed ID: 19006381
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  • 3. Design, synthesis, derivatization, and structure-activity relationships of simplified, tricyclic, 1,2,4-trioxane alcohol analogues of the antimalarial artemisinin.
    Cumming JN, Wang D, Park SB, Shapiro TA, Posner GH.
    J Med Chem; 1998 Mar 12; 41(6):952-64. PubMed ID: 9526569
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  • 4. Trioxaferroquines as new hybrid antimalarial drugs.
    Bellot F, Coslédan F, Vendier L, Brocard J, Meunier B, Robert A.
    J Med Chem; 2010 May 27; 53(10):4103-9. PubMed ID: 20443628
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  • 5. Potentiation of antimalarial drug action by chlorpheniramine against multidrug-resistant Plasmodium falciparum in vitro.
    Nakornchai S, Konthiang P.
    Parasitol Int; 2006 Sep 27; 55(3):195-9. PubMed ID: 16750932
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  • 6. In vitro activity of artemisone compared with artesunate against Plasmodium falciparum.
    Ramharter M, Burkhardt D, Nemeth J, Adegnika AA, Kremsner PG.
    Am J Trop Med Hyg; 2006 Oct 27; 75(4):637-9. PubMed ID: 17038685
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  • 8. Novel spiroanellated 1,2,4-trioxanes with high in vitro antimalarial activities.
    Griesbeck AG, El-Idreesy TT, Höinck LO, Lex J, Brun R.
    Bioorg Med Chem Lett; 2005 Feb 01; 15(3):595-7. PubMed ID: 15664819
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  • 9. Design, Synthesis, and Biological Evaluation of Novel 1,2,4-Trioxanes as Potential Antimalarial Agents.
    Gupta AK, Varshney K, Kumar V, Srivastava K, Pant AB, Puri SK, Saxena AK.
    Arch Pharm (Weinheim); 2017 Apr 01; 350(3-4):. PubMed ID: 28207169
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  • 10. Synthesis and biological evaluation of extraordinarily potent C-10 carba artemisinin dimers against P. falciparum malaria parasites and HL-60 cancer cells.
    Chadwick J, Mercer AE, Park BK, Cosstick R, O'Neill PM.
    Bioorg Med Chem; 2009 Feb 01; 17(3):1325-38. PubMed ID: 19136263
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  • 12. Rationale design of biotinylated antimalarial endoperoxide carbon centered radical prodrugs for applications in proteomics.
    Barton V, Ward SA, Chadwick J, Hill A, O'Neill PM.
    J Med Chem; 2010 Jun 10; 53(11):4555-9. PubMed ID: 20476788
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  • 13. Modular synthesis and in vitro and in vivo antimalarial assessment of C-10 pyrrole mannich base derivatives of artemisinin.
    Pacorel B, Leung SC, Stachulski AV, Davies J, Vivas L, Lander H, Ward SA, Kaiser M, Brun R, O'Neill PM.
    J Med Chem; 2010 Jan 28; 53(2):633-40. PubMed ID: 19957999
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  • 15. Synthesis, in vitro and in vivo antimalarial assessment of sulfide, sulfone and vinyl amide-substituted 1,2,4-trioxanes prepared via thiol-olefin co-oxygenation (TOCO) of allylic alcohols.
    Amewu R, Gibbons P, Mukhtar A, Stachulski AV, Ward SA, Hall C, Rimmer K, Davies J, Vivas L, Bacsa J, Mercer AE, Nixon G, Stocks PA, O'Neill PM.
    Org Biomol Chem; 2010 May 07; 8(9):2068-77. PubMed ID: 20401383
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  • 18. Synthesis of N1-arylidene-N2-quinolyl- and N2-acrydinylhydrazones as potent antimalarial agents active against CQ-resistant P. falciparum strains.
    Gemma S, Kukreja G, Fattorusso C, Persico M, Romano MP, Altarelli M, Savini L, Campiani G, Fattorusso E, Basilico N, Taramelli D, Yardley V, Butini S.
    Bioorg Med Chem Lett; 2006 Oct 15; 16(20):5384-8. PubMed ID: 16890433
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  • 19. Novel series of 1,2,4-trioxane derivatives as antimalarial agents.
    Rudrapal M, Chetia D, Singh V.
    J Enzyme Inhib Med Chem; 2017 Dec 15; 32(1):1159-1173. PubMed ID: 28870093
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  • 20. Pharmacophore modeling of substituted 1,2,4-Trioxanes for quantitative prediction of their antimalarial activity.
    Gupta AK, Chakroborty S, Srivastava K, Puri SK, Saxena AK.
    J Chem Inf Model; 2010 Aug 23; 50(8):1510-20. PubMed ID: 20726605
    [Abstract] [Full Text] [Related]

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