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197 related items for PubMed ID: 16229088

  • 1. A novel mutation in the juxtamembrane intracellular sequence of the granulocyte colony-stimulating factor (G-CSF) receptor gene in a patient with severe congenital neutropenia augments GCSF proliferation activity but not through the MAP kinase cascade.
    Yokoyama T, Okamura S, Asano Y, Kamezaki K, Numata A, Kakumitsu H, Shide K, Nakashima H, Taisuke K, Sekine Y, Mizuno Y, Okamura J, Matsuda T, Harada M, Yoshiyuki N, Shimoda K.
    Int J Hematol; 2005 Jul; 82(1):28-34. PubMed ID: 16229088
    [Abstract] [Full Text] [Related]

  • 2. Mutations in the gene for the granulocyte colony-stimulating-factor receptor in patients with acute myeloid leukemia preceded by severe congenital neutropenia.
    Dong F, Brynes RK, Tidow N, Welte K, Löwenberg B, Touw IP.
    N Engl J Med; 1995 Aug 24; 333(8):487-93. PubMed ID: 7542747
    [Abstract] [Full Text] [Related]

  • 3. Sustained receptor activation and hyperproliferation in response to granulocyte colony-stimulating factor (G-CSF) in mice with a severe congenital neutropenia/acute myeloid leukemia-derived mutation in the G-CSF receptor gene.
    Hermans MH, Antonissen C, Ward AC, Mayen AE, Ploemacher RE, Touw IP.
    J Exp Med; 1999 Feb 15; 189(4):683-92. PubMed ID: 9989983
    [Abstract] [Full Text] [Related]

  • 4. Combined corticosteroid/granulocyte colony-stimulating factor (G-CSF) therapy in the treatment of severe congenital neutropenia unresponsive to G-CSF: Activated glucocorticoid receptors synergize with G-CSF signals.
    Dror Y, Ward AC, Touw IP, Freedman MH.
    Exp Hematol; 2000 Dec 15; 28(12):1381-9. PubMed ID: 11146160
    [Abstract] [Full Text] [Related]

  • 5. Novel point mutation in the extracellular domain of the granulocyte colony-stimulating factor (G-CSF) receptor in a case of severe congenital neutropenia hyporesponsive to G-CSF treatment.
    Ward AC, van Aesch YM, Gits J, Schelen AM, de Koning JP, van Leeuwen D, Freedman MH, Touw IP.
    J Exp Med; 1999 Aug 16; 190(4):497-507. PubMed ID: 10449521
    [Abstract] [Full Text] [Related]

  • 6. The carboxyl terminus of the granulocyte colony-stimulating factor receptor, truncated in patients with severe congenital neutropenia/acute myeloid leukemia, is required for SH2-containing phosphatase-1 suppression of Stat activation.
    Dong F, Qiu Y, Yi T, Touw IP, Larner AC.
    J Immunol; 2001 Dec 01; 167(11):6447-52. PubMed ID: 11714811
    [Abstract] [Full Text] [Related]

  • 7. Increased granulocyte colony-stimulating factor responsiveness but normal resting granulopoiesis in mice carrying a targeted granulocyte colony-stimulating factor receptor mutation derived from a patient with severe congenital neutropenia.
    McLemore ML, Poursine-Laurent J, Link DC.
    J Clin Invest; 1998 Aug 01; 102(3):483-92. PubMed ID: 9691084
    [Abstract] [Full Text] [Related]

  • 8. Clinical relevance of point mutations in the cytoplasmic domain of the granulocyte colony-stimulating factor receptor gene in patients with severe congenital neutropenia.
    Tidow N, Pilz C, Teichmann B, Müller-Brechlin A, Germeshausen M, Kasper B, Rauprich P, Sykora KW, Welte K.
    Blood; 1997 Apr 01; 89(7):2369-75. PubMed ID: 9116280
    [Abstract] [Full Text] [Related]

  • 9. Structural abnormalities in the G-CSF receptor in severe congenital neutropenia.
    Deshpande RV, Lalezari P, Pergolizzi RG, Moore MA.
    J Hematother Stem Cell Res; 1999 Aug 01; 8(4):411-20. PubMed ID: 10634179
    [Abstract] [Full Text] [Related]

  • 10. Identification of a nonsense mutation in the granulocyte-colony-stimulating factor receptor in severe congenital neutropenia.
    Dong F, Hoefsloot LH, Schelen AM, Broeders CA, Meijer Y, Veerman AJ, Touw IP, Löwenberg B.
    Proc Natl Acad Sci U S A; 1994 May 10; 91(10):4480-4. PubMed ID: 7514305
    [Abstract] [Full Text] [Related]

  • 11. Novel variant isoform of G-CSF receptor involved in induction of proliferation of FDCP-2 cells: relevance to the pathogenesis of myelodysplastic syndrome.
    Awaya N, Uchida H, Miyakawa Y, Kinjo K, Matsushita H, Nakajima H, Ikeda Y, Kizaki M.
    J Cell Physiol; 2002 Jun 10; 191(3):327-35. PubMed ID: 12012328
    [Abstract] [Full Text] [Related]

  • 12. Neutrophil elastase and granulocyte colony-stimulating factor receptor mutation analyses and leukemia evolution in severe congenital neutropenia patients belonging to the original Kostmann family in northern Sweden.
    Carlsson G, Aprikyan AA, Ericson KG, Stein S, Makaryan V, Dale DC, Nordenskjöld M, Fadeel B, Palmblad J, Hentera JI.
    Haematologica; 2006 May 10; 91(5):589-95. PubMed ID: 16670064
    [Abstract] [Full Text] [Related]

  • 13. Spontaneous remission of granulocyte colony-stimulating factor-associated leukemia in a child with severe congenital neutropenia.
    Jeha S, Chan KW, Aprikyan AG, Hoots WK, Culbert S, Zietz H, Dale DC, Albitar M.
    Blood; 2000 Nov 15; 96(10):3647-9. PubMed ID: 11071667
    [Abstract] [Full Text] [Related]

  • 14. Frequency of point mutations in the gene for the G-CSF receptor in patients with chronic neutropenia undergoing G-CSF therapy.
    Tidow N, Pilz C, Kasper B, Welte K.
    Stem Cells; 1997 Nov 15; 15 Suppl 1():113-9; discussion 120. PubMed ID: 9368331
    [Abstract] [Full Text] [Related]

  • 15. G-CSF receptor mutations in patients with severe congenital neutropenia do not abrogate Jak2 activation and stat1/stat3 translocation.
    Herbst A, Koester M, Wirth D, Hauser H, Welte K.
    Ann N Y Acad Sci; 1999 Apr 30; 872():320-5; discussion 325-7. PubMed ID: 10372134
    [Abstract] [Full Text] [Related]

  • 16. Severe congenital neutropenia terminating in acute myeloid leukemia: disease progression associated with mutations in the granulocyte-colony stimulating factor receptor gene.
    Touw IP, Dong F.
    Leuk Res; 1996 Aug 30; 20(8):629-31. PubMed ID: 8913314
    [Abstract] [Full Text] [Related]

  • 17. Granulocyte colony-stimulating factor receptor signaling: implications for G-CSF responses and leukemic progression in severe congenital neutropenia.
    Touw IP, Palande K, Beekman R.
    Hematol Oncol Clin North Am; 2013 Feb 30; 27(1):61-73, viii. PubMed ID: 23351988
    [Abstract] [Full Text] [Related]

  • 18. Mutations in the granulocyte colony-stimulating factor receptor gene in patients with severe congenital neutropenia.
    Dong F, Dale DC, Bonilla MA, Freedman M, Fasth A, Neijens HJ, Palmblad J, Briars GL, Carlsson G, Veerman AJ, Welte K, Löwenberg B, Touw IP.
    Leukemia; 1997 Jan 30; 11(1):120-5. PubMed ID: 9001427
    [Abstract] [Full Text] [Related]

  • 19. Impaired neutrophil maturation in truncated murine G-CSF receptor-transgenic mice.
    Mitsui T, Watanabe S, Taniguchi Y, Hanada S, Ebihara Y, Sato T, Heike T, Mitsuyama M, Nakahata T, Tsuji K.
    Blood; 2003 Apr 15; 101(8):2990-5. PubMed ID: 12672695
    [Abstract] [Full Text] [Related]

  • 20. Granulocyte colony-stimulating factor receptor mutations in severe congenital neutropenia transforming to acute myelogenous leukemia confer resistance to apoptosis and enhance cell survival.
    Hunter MG, Avalos BR.
    Blood; 2000 Mar 15; 95(6):2132-7. PubMed ID: 10706885
    [Abstract] [Full Text] [Related]

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