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167 related items for PubMed ID: 16230379

  • 1. Ku86 modulates DNA topoisomerase I-mediated radiosensitization, but not cytotoxicity, in mammalian cells.
    Shih SJ, Erbele T, Chen AY.
    Cancer Res; 2005 Oct 15; 65(20):9194-9. PubMed ID: 16230379
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  • 2. Analysis of the DNA replication competence of the xrs-5 mutant cells defective in Ku86.
    Matheos D, Novac O, Price GB, Zannis-Hadjopoulos M.
    J Cell Sci; 2003 Jan 01; 116(Pt 1):111-24. PubMed ID: 12456721
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  • 3. Differential requirement of DNA replication for the cytotoxicity of DNA topoisomerase I and II inhibitors in Chinese hamster DC3F cells.
    Holm C, Covey JM, Kerrigan D, Pommier Y.
    Cancer Res; 1989 Nov 15; 49(22):6365-8. PubMed ID: 2553254
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  • 4. Mammalian DNA topoisomerase I mediates the enhancement of radiation cytotoxicity by camptothecin derivatives.
    Chen AY, Okunieff P, Pommier Y, Mitchell JB.
    Cancer Res; 1997 Apr 15; 57(8):1529-36. PubMed ID: 9108456
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  • 5. Silatecan DB-67 is a novel DNA topoisomerase I-targeted radiation sensitizer.
    Chen AY, Shih SJ, Garriques LN, Rothenberg ML, Hsiao M, Curran DP.
    Mol Cancer Ther; 2005 Feb 15; 4(2):317-24. PubMed ID: 15713902
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  • 9. An antisense oligonucleotide targeted to human Ku86 messenger RNA sensitizes M059K malignant glioma cells to ionizing radiation, bleomycin, and etoposide but not DNA cross-linking agents.
    Belenkov AI, Paiement JP, Panasci LC, Monia BP, Chow TY.
    Cancer Res; 2002 Oct 15; 62(20):5888-96. PubMed ID: 12384553
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  • 12. DNA repair enzyme, O6-methylguanine DNA methyltransferase, modulates cytotoxicity of camptothecin-derived topoisomerase I inhibitors.
    Kuo CC, Liu JF, Chang JY.
    J Pharmacol Exp Ther; 2006 Feb 15; 316(2):946-54. PubMed ID: 16258022
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  • 13. Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA:DNA-PK complexes.
    Shao RG, Cao CX, Zhang H, Kohn KW, Wold MS, Pommier Y.
    EMBO J; 1999 Mar 01; 18(5):1397-406. PubMed ID: 10064605
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  • 14. The CHO XRCC1 mutant, EM9, deficient in DNA ligase III activity, exhibits hypersensitivity to camptothecin independent of DNA replication.
    Barrows LR, Holden JA, Anderson M, D'Arpa P.
    Mutat Res; 1998 Aug 07; 408(2):103-10. PubMed ID: 9739812
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  • 15. Differential cytotoxic pathways of topoisomerase I and II anticancer agents after overexpression of the E2F-1/DP-1 transcription factor complex.
    Hofland K, Petersen BO, Falck J, Helin K, Jensen PB, Sehested M.
    Clin Cancer Res; 2000 Apr 07; 6(4):1488-97. PubMed ID: 10778981
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  • 16. End-joining deficiency and radiosensitization induced by gemcitabine.
    van Putten JWG, Groen HJM, Smid K, Peters GJ, Kampinga HH.
    Cancer Res; 2001 Feb 15; 61(4):1585-91. PubMed ID: 11245469
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  • 19. DNA strand break rejoining defect in xrs-6 is complemented by transfection with the human Ku80 gene.
    Ross GM, Eady JJ, Mithal NP, Bush C, Steel GG, Jeggo PA, McMillan TJ.
    Cancer Res; 1995 Mar 15; 55(6):1235-8. PubMed ID: 7882315
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  • 20. The role of the DNA mismatch repair system in the cytotoxicity of the topoisomerase inhibitors camptothecin and etoposide to human colorectal cancer cells.
    Jacob S, Aguado M, Fallik D, Praz F.
    Cancer Res; 2001 Sep 01; 61(17):6555-62. PubMed ID: 11522654
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