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Journal Abstract Search

96 related items for PubMed ID: 16230405

  • 1. Lysophosphatidic acid acyltransferase-beta is a prognostic marker and therapeutic target in gynecologic malignancies.
    Springett GM, Bonham L, Hummer A, Linkov I, Misra D, Ma C, Pezzoni G, Di Giovine S, Singer J, Kawasaki H, Spriggs D, Soslow R, Dupont J.
    Cancer Res; 2005 Oct 15; 65(20):9415-25. PubMed ID: 16230405
    [Abstract] [Full Text] [Related]

  • 2. Induction of apoptosis using inhibitors of lysophosphatidic acid acyltransferase-beta and anti-CD20 monoclonal antibodies for treatment of human non-Hodgkin's lymphomas.
    Pagel JM, Laugen C, Bonham L, Hackman RC, Hockenbery DM, Bhatt R, Hollenback D, Carew H, Singer JW, Press OW.
    Clin Cancer Res; 2005 Jul 01; 11(13):4857-66. PubMed ID: 16000584
    [Abstract] [Full Text] [Related]

  • 3. Antileukemic activity of lysophosphatidic acid acyltransferase-beta inhibitor CT32228 in chronic myelogenous leukemia sensitive and resistant to imatinib.
    La Rosée P, Jia T, Demehri S, Härtel N, de Vries P, Bonham L, Hollenback D, Singer JW, Melo JV, Druker BJ, Deininger MW.
    Clin Cancer Res; 2006 Nov 01; 12(21):6540-6. PubMed ID: 17085669
    [Abstract] [Full Text] [Related]

  • 4. Effect of lysophosphatidic acid acyltransferase-beta inhibition in acute leukemia.
    Douvas MG, Hogan KN, Ji Y, Hollenback D, Bonham L, Singer JW, Mitchell BS.
    Leuk Res; 2006 Aug 01; 30(8):1027-36. PubMed ID: 16488473
    [Abstract] [Full Text] [Related]

  • 5. Lysophosphatidic acid acyltransferase-beta (LPAAT-beta) is highly expressed in advanced ovarian cancer and is associated with aggressive histology and poor survival.
    Diefenbach CS, Soslow RA, Iasonos A, Linkov I, Hedvat C, Bonham L, Singer J, Barakat RR, Aghajanian C, Dupont J.
    Cancer; 2006 Oct 01; 107(7):1511-9. PubMed ID: 16944535
    [Abstract] [Full Text] [Related]

  • 6. Lysophosphatidic acid acyltransferase-beta: a novel target for induction of tumour cell apoptosis.
    Bonham L, Leung DW, White T, Hollenback D, Klein P, Tulinsky J, Coon M, de Vries P, Singer JW.
    Expert Opin Ther Targets; 2003 Oct 01; 7(5):643-61. PubMed ID: 14498826
    [Abstract] [Full Text] [Related]

  • 7. Role of nongenomic activation of phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase 1/2 pathways in 1,25D3-mediated apoptosis in squamous cell carcinoma cells.
    Ma Y, Yu WD, Kong RX, Trump DL, Johnson CS.
    Cancer Res; 2006 Aug 15; 66(16):8131-8. PubMed ID: 16912191
    [Abstract] [Full Text] [Related]

  • 8. Expression of lysophosphatidic acid acyltransferase beta (LPAAT-beta) in ovarian carcinoma: correlation with tumour grading and prognosis.
    Niesporek S, Denkert C, Weichert W, Köbel M, Noske A, Sehouli J, Singer JW, Dietel M, Hauptmann S.
    Br J Cancer; 2005 May 09; 92(9):1729-36. PubMed ID: 15841084
    [Abstract] [Full Text] [Related]

  • 9. Estrogen and progestin regulate metastasis through the PI3K/AKT pathway in human ovarian cancer.
    Hua K, Feng W, Cao Q, Zhou X, Lu X, Feng Y.
    Int J Oncol; 2008 Nov 09; 33(5):959-67. PubMed ID: 18949358
    [Abstract] [Full Text] [Related]

  • 10. Antimyeloma activity of the orally bioavailable dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235.
    McMillin DW, Ooi M, Delmore J, Negri J, Hayden P, Mitsiades N, Jakubikova J, Maira SM, Garcia-Echeverria C, Schlossman R, Munshi NC, Richardson PG, Anderson KC, Mitsiades CS.
    Cancer Res; 2009 Jul 15; 69(14):5835-42. PubMed ID: 19584292
    [Abstract] [Full Text] [Related]

  • 11. Mammalian target of rapamycin, a molecular target in squamous cell carcinomas of the head and neck.
    Amornphimoltham P, Patel V, Sodhi A, Nikitakis NG, Sauk JJ, Sausville EA, Molinolo AA, Gutkind JS.
    Cancer Res; 2005 Nov 01; 65(21):9953-61. PubMed ID: 16267020
    [Abstract] [Full Text] [Related]

  • 12. Enzastaurin, a protein kinase C beta inhibitor, suppresses signaling through the ribosomal S6 kinase and bad pathways and induces apoptosis in human gastric cancer cells.
    Lee KW, Kim SG, Kim HP, Kwon E, You J, Choi HJ, Park JH, Kang BC, Im SA, Kim TY, Kim WH, Bang YJ.
    Cancer Res; 2008 Mar 15; 68(6):1916-26. PubMed ID: 18339873
    [Abstract] [Full Text] [Related]

  • 13. Nitric oxide in physiologic concentrations targets the translational machinery to increase the proliferation of human breast cancer cells: involvement of mammalian target of rapamycin/eIF4E pathway.
    Pervin S, Singh R, Hernandez E, Wu G, Chaudhuri G.
    Cancer Res; 2007 Jan 01; 67(1):289-99. PubMed ID: 17210710
    [Abstract] [Full Text] [Related]

  • 14. Semaphorin SEMA3F affects multiple signaling pathways in lung cancer cells.
    Potiron VA, Sharma G, Nasarre P, Clarhaut JA, Augustin HG, Gemmill RM, Roche J, Drabkin HA.
    Cancer Res; 2007 Sep 15; 67(18):8708-15. PubMed ID: 17875711
    [Abstract] [Full Text] [Related]

  • 15. Lysophosphatidic acid acyltransferase beta regulates mTOR signaling.
    Blaskovich MA, Yendluri V, Lawrence HR, Lawrence NJ, Sebti SM, Springett GM.
    PLoS One; 2013 Sep 15; 8(10):e78632. PubMed ID: 24205284
    [Abstract] [Full Text] [Related]

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  • 17. Loss of beta4 integrin subunit reduces the tumorigenicity of MCF7 mammary cells and causes apoptosis upon hormone deprivation.
    Bon G, Folgiero V, Bossi G, Felicioni L, Marchetti A, Sacchi A, Falcioni R.
    Clin Cancer Res; 2006 Jun 01; 12(11 Pt 1):3280-7. PubMed ID: 16740748
    [Abstract] [Full Text] [Related]

  • 18. Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.
    Ou YC, Yang CR, Cheng CL, Raung SL, Hung YY, Chen CJ.
    Eur J Pharmacol; 2007 Jun 01; 563(1-3):49-60. PubMed ID: 17341418
    [Abstract] [Full Text] [Related]

  • 19. ErbB2 increases vascular endothelial growth factor protein synthesis via activation of mammalian target of rapamycin/p70S6K leading to increased angiogenesis and spontaneous metastasis of human breast cancer cells.
    Klos KS, Wyszomierski SL, Sun M, Tan M, Zhou X, Li P, Yang W, Yin G, Hittelman WN, Yu D.
    Cancer Res; 2006 Feb 15; 66(4):2028-37. PubMed ID: 16489002
    [Abstract] [Full Text] [Related]

  • 20. RNA interference-mediated silencing of the phosphatidylinositol 3-kinase catalytic subunit attenuates growth of human ovarian cancer cells in vitroand in vivo.
    Zhang X, Deng HX, Zhao X, Su D, Chen XC, Chen LJ, Wei YQ, Zhong Q, Li ZY, He X, Yi T.
    Oncology; 2009 Feb 15; 77(1):22-32. PubMed ID: 19440000
    [Abstract] [Full Text] [Related]

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