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485 related items for PubMed ID: 16239721

  • 21. Crystal structure of the ternary complex of E. coli purine nucleoside phosphorylase with formycin B, a structural analogue of the substrate inosine, and phosphate (Sulphate) at 2.1 A resolution.
    Koellner G, Luić M, Shugar D, Saenger W, Bzowska A.
    J Mol Biol; 1998 Jul 03; 280(1):153-66. PubMed ID: 9653038
    [Abstract] [Full Text] [Related]

  • 22. Crystal structure of Schistosoma purine nucleoside phosphorylase complexed with a novel monocyclic inhibitor.
    Pereira HM, Berdini V, Ferri MR, Cleasby A, Garratt RC.
    Acta Trop; 2010 May 03; 114(2):97-102. PubMed ID: 20122887
    [Abstract] [Full Text] [Related]

  • 23. Exploring structure-activity relationships of transition state analogues of human purine nucleoside phosphorylase.
    Evans GB, Furneaux RH, Lewandowicz A, Schramm VL, Tyler PC.
    J Med Chem; 2003 Jul 17; 46(15):3412-23. PubMed ID: 12852771
    [Abstract] [Full Text] [Related]

  • 24. Adenosine binding to low-molecular-weight purine nucleoside phosphorylase: the structural basis for recognition based on its complex with the enzyme from Schistosoma mansoni.
    Pereira HM, Rezende MM, Castilho MS, Oliva G, Garratt RC.
    Acta Crystallogr D Biol Crystallogr; 2010 Jan 17; 66(Pt 1):73-9. PubMed ID: 20057051
    [Abstract] [Full Text] [Related]

  • 25. Structure of human PNP complexed with ligands.
    Canduri F, Silva RG, dos Santos DM, Palma MS, Basso LA, Santos DS, de Azevedo WF.
    Acta Crystallogr D Biol Crystallogr; 2005 Jul 17; 61(Pt 7):856-62. PubMed ID: 15983407
    [Abstract] [Full Text] [Related]

  • 26. Synthesis and biological evaluation of 9-deazaguanine derivatives connected by a linker to difluoromethylene phosphonic acid as multi-substrate analogue inhibitors of PNP.
    Hikishima S, Hashimoto M, Magnowska L, Bzowska A, Yokomatsu T.
    Bioorg Med Chem Lett; 2007 Aug 01; 17(15):4173-7. PubMed ID: 17544667
    [Abstract] [Full Text] [Related]

  • 27. [Tight binding transition state analogues of purine nucleoside phosphorylase--meaning, design and properties].
    Lewandowicz A.
    Postepy Biochem; 2004 Aug 01; 50(3):218-27. PubMed ID: 15822751
    [No Abstract] [Full Text] [Related]

  • 28. New phosphate binding sites in the crystal structure of Escherichia coli purine nucleoside phosphorylase complexed with phosphate and formycin A.
    Štefanić Z, Narczyk M, Mikleušević G, Wielgus-Kutrowska B, Bzowska A, Luić M.
    FEBS Lett; 2012 Apr 05; 586(7):967-71. PubMed ID: 22569248
    [Abstract] [Full Text] [Related]

  • 29. Fluorophosphonylated nucleoside derivatives as new series of thymidine phosphorylase multisubstrate inhibitors.
    Diab SA, De Schutter C, Muzard M, Plantier-Royon R, Pfund E, Lequeux T.
    J Med Chem; 2012 Mar 22; 55(6):2758-68. PubMed ID: 22372816
    [Abstract] [Full Text] [Related]

  • 30. Mechanism of thiol-supported arsenate reduction mediated by phosphorolytic-arsenolytic enzymes: II. Enzymatic formation of arsenylated products susceptible for reduction to arsenite by thiols.
    Gregus Z, Roos G, Geerlings P, Németi B.
    Toxicol Sci; 2009 Aug 22; 110(2):282-92. PubMed ID: 19478237
    [Abstract] [Full Text] [Related]

  • 31. Purine nucleoside phosphorylase. 2. Catalytic mechanism.
    Erion MD, Stoeckler JD, Guida WC, Walter RL, Ealick SE.
    Biochemistry; 1997 Sep 30; 36(39):11735-48. PubMed ID: 9305963
    [Abstract] [Full Text] [Related]

  • 32. Kinetics and crystal structure of human purine nucleoside phosphorylase in complex with 7-methyl-6-thio-guanosine.
    Silva RG, Pereira JH, Canduri F, de Azevedo WF, Basso LA, Santos DS.
    Arch Biochem Biophys; 2005 Oct 01; 442(1):49-58. PubMed ID: 16154528
    [Abstract] [Full Text] [Related]

  • 33. Two- and three-dimensional quantitative structure-activity relationships for a series of purine nucleoside phosphorylase inhibitors.
    Castilho MS, Postigo MP, de Paula CB, Montanari CA, Oliva G, Andricopulo AD.
    Bioorg Med Chem; 2006 Jan 15; 14(2):516-27. PubMed ID: 16203153
    [Abstract] [Full Text] [Related]

  • 34. Transition state structure of purine nucleoside phosphorylase and principles of atomic motion in enzymatic catalysis.
    Fedorov A, Shi W, Kicska G, Fedorov E, Tyler PC, Furneaux RH, Hanson JC, Gainsford GJ, Larese JZ, Schramm VL, Almo SC.
    Biochemistry; 2001 Jan 30; 40(4):853-60. PubMed ID: 11170405
    [Abstract] [Full Text] [Related]

  • 35. Structural basis for selective inhibition of purine nucleoside phosphorylase from Schistosoma mansoni: kinetic and structural studies.
    Castilho MS, Postigo MP, Pereira HM, Oliva G, Andricopulo AD.
    Bioorg Med Chem; 2010 Feb 15; 18(4):1421-7. PubMed ID: 20129792
    [Abstract] [Full Text] [Related]

  • 36. Nucleoside phosphonic acids in thymidine phosphorylase inhibition: structure-activity relationship.
    Panova N, Kosiová I, Petrová M, Vanĕk V, Liboska R, Kovacková S, Kocalka P, Králíková S, Tocík Z, Páv O, Paces O, Rejman D, Rosenberg I.
    Nucleic Acids Symp Ser (Oxf); 2008 Feb 15; (52):665-6. PubMed ID: 18776555
    [Abstract] [Full Text] [Related]

  • 37. Structure-activity relationships for a class of inhibitors of purine nucleoside phosphorylase.
    Farutin V, Masterson L, Andricopulo AD, Cheng J, Riley B, Hakimi R, Frazer JW, Cordes EH.
    J Med Chem; 1999 Jul 01; 42(13):2422-31. PubMed ID: 10395483
    [Abstract] [Full Text] [Related]

  • 38. Calf spleen purine nucleoside phosphorylase complexed with substrates and substrate analogues.
    Mao C, Cook WJ, Zhou M, Federov AA, Almo SC, Ealick SE.
    Biochemistry; 1998 May 19; 37(20):7135-46. PubMed ID: 9585525
    [Abstract] [Full Text] [Related]

  • 39. Design of purine nucleoside phosphorylase inhibitors.
    Stoeckler JD, Ealick SE, Bugg CE, Parks RE.
    Fed Proc; 1986 Nov 19; 45(12):2773-8. PubMed ID: 3095150
    [Abstract] [Full Text] [Related]

  • 40. Syntheses of pyrimidine acyclic nucleoside phosphonates as potent inhibitors of thymidine phosphorylase (PD-ECGF) from SD-lymphoma.
    Pomeisl K, Votruba I, Holý A, Pohl R.
    Nucleosides Nucleotides Nucleic Acids; 2007 Nov 19; 26(8-9):1025-8. PubMed ID: 18058530
    [Abstract] [Full Text] [Related]

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