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Journal Abstract Search

485 related items for PubMed ID: 16239721

  • 41. Kinetics of binding of multisubstrate analogue inhibitor (2-amino-9-[2-(phosphonomethoxy)ethyl]-6-sulfanylpurine) with trimeric purine nucleoside phosphorylase.
    Antosiewicz J, Wielgus-Kutrowska B, Długosz M, Holy A, Bzowska A.
    Nucleosides Nucleotides Nucleic Acids; 2007; 26(8-9):969-74. PubMed ID: 18058519
    [Abstract] [Full Text] [Related]

  • 42. Synthesis and biological activity of a novel class of purine nucleoside phosphorylase inhibitors.
    Morris PE, Elliott AJ, Walton SP, Williams CH, Montgomery JA.
    Nucleosides Nucleotides Nucleic Acids; 2000; 19(1-2):379-404. PubMed ID: 10772722
    [No Abstract] [Full Text] [Related]

  • 43. Interactions of potent multisubstrate analogue inhibitors with purine nucleoside phosphorylase from calf spleen--kinetic and spectrofluorimetric studies.
    Iwanow M, Magnowska L, Yokomatsu T, Shibuya S, Bzowska A.
    Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):1567-70. PubMed ID: 14565467
    [Abstract] [Full Text] [Related]

  • 44. N-phosphonocarbonylpyrrolidine derivatives of guanine: a new class of bi-substrate inhibitors of human purine nucleoside phosphorylase.
    Rejman D, Panova N, Klener P, Maswabi B, Pohl R, Rosenberg I.
    J Med Chem; 2012 Feb 23; 55(4):1612-21. PubMed ID: 22264015
    [Abstract] [Full Text] [Related]

  • 45. Exploring new inhibitors of Plasmodium falciparum purine nucleoside phosphorylase.
    Cui H, Ruda GF, Carrero-Lérida J, Ruiz-Pérez LM, Gilbert IH, González-Pacanowska D.
    Eur J Med Chem; 2010 Nov 23; 45(11):5140-9. PubMed ID: 20817362
    [Abstract] [Full Text] [Related]

  • 46. Synthesis, anti-HIV activity, and resistance profiles of ribose modified nucleoside phosphonates.
    Mackman RL, Boojamra CG, Prasad V, Zhang L, Lin KY, Petrakovsky O, Babusis D, Chen J, Douglas J, Grant D, Hui HC, Kim CU, Markevitch DY, Vela J, Ray A, Cihlar T.
    Bioorg Med Chem Lett; 2007 Dec 15; 17(24):6785-9. PubMed ID: 18029175
    [Abstract] [Full Text] [Related]

  • 47. 6-Methylpurine derived sugar modified nucleosides: Synthesis and in vivo antitumor activity in D54 tumor expressing M64V-Escherichia coli purine nucleoside phosphorylase.
    Hassan AEA, Abou-Elkhair RAI, Parker WB, Allan PW, Secrist JA.
    Eur J Med Chem; 2016 Jan 27; 108():616-622. PubMed ID: 26724729
    [Abstract] [Full Text] [Related]

  • 48. Design and evaluation of dihydroxytetrahydro-1H-pyrrolo[2,1-c]- [1,4]benzothiazines as conformationally restricted transition-state inhibitors of beta-ribosidases.
    Gao L, Hollingsworth RI.
    J Org Chem; 2005 Oct 28; 70(22):9013-6. PubMed ID: 16238341
    [Abstract] [Full Text] [Related]

  • 49. Structures of Plasmodium falciparum purine nucleoside phosphorylase complexed with sulfate and its natural substrate inosine.
    Schnick C, Robien MA, Brzozowski AM, Dodson EJ, Murshudov GN, Anderson L, Luft JR, Mehlin C, Hol WG, Brannigan JA, Wilkinson AJ.
    Acta Crystallogr D Biol Crystallogr; 2005 Sep 28; 61(Pt 9):1245-54. PubMed ID: 16131758
    [Abstract] [Full Text] [Related]

  • 50. Phosphate activation in the ground state of purine nucleoside phosphorylase.
    Deng H, Murkin AS, Schramm VL.
    J Am Chem Soc; 2006 Jun 21; 128(24):7765-71. PubMed ID: 16771490
    [Abstract] [Full Text] [Related]

  • 51. 9-Deazaguanine derivatives connected by a linker to difluoromethylene phosphonic acid are slow-binding picomolar inhibitors of trimeric purine nucleoside phosphorylase.
    Breer K, Glavas-Obrovac L, Suver M, Hikishima S, Hashimoto M, Yokomatsu T, Wielgus-Kutrowska B, Magnowska L, Bzowska A.
    FEBS J; 2010 Apr 21; 277(7):1747-60. PubMed ID: 20193043
    [Abstract] [Full Text] [Related]

  • 52. 7-Deazapurine 2'-deoxyribofuranosides are noncleavable competitive inhibitors of Escherichia coli purine nucleoside phosphorylase (PNP).
    Bzowska A, Kazimierczuk Z, Seela F.
    Acta Biochim Pol; 1998 Apr 21; 45(3):755-68. PubMed ID: 9918502
    [Abstract] [Full Text] [Related]

  • 53. Purine nucleoside phosphorylase. 3. Reversal of purine base specificity by site-directed mutagenesis.
    Stoeckler JD, Poirot AF, Smith RM, Parks RE, Ealick SE, Takabayashi K, Erion MD.
    Biochemistry; 1997 Sep 30; 36(39):11749-56. PubMed ID: 9305964
    [Abstract] [Full Text] [Related]

  • 54. Purine nucleoside phosphorylase as a cytosolic arsenate reductase.
    Gregus Z, Németi B.
    Toxicol Sci; 2002 Nov 30; 70(1):13-9. PubMed ID: 12388830
    [Abstract] [Full Text] [Related]

  • 55. Escherichia coli purine nucleoside phosphorylase II, the product of the xapA gene.
    Dandanell G, Szczepanowski RH, Kierdaszuk B, Shugar D, Bochtler M.
    J Mol Biol; 2005 Apr 22; 348(1):113-25. PubMed ID: 15808857
    [Abstract] [Full Text] [Related]

  • 56. Synthesis of second-generation transition state analogues of human purine nucleoside phosphorylase.
    Evans GB, Furneaux RH, Lewandowicz A, Schramm VL, Tyler PC.
    J Med Chem; 2003 Nov 20; 46(24):5271-6. PubMed ID: 14613329
    [Abstract] [Full Text] [Related]

  • 57. Molecular modeling, dynamics and docking studies of purine nucleoside phosphorylase from Streptococcus pyogenes.
    Timmers LF, Caceres RA, Dias R, Basso LA, Santos DS, de Azevedo WF.
    Biophys Chem; 2009 Jun 20; 142(1-3):7-16. PubMed ID: 19282092
    [Abstract] [Full Text] [Related]

  • 58. Structural diversity of nucleoside phosphonic acids as a key factor in the discovery of potent inhibitors of rat T-cell lymphoma thymidine phosphorylase.
    Kocalka P, Rejman D, Vanek V, Rinnová M, Tomecková I, Králíková S, Petrová M, Páv O, Pohl R, Budesínský M, Liboska R, Tocík Z, Panova N, Votruba I, Rosenberg I.
    Bioorg Med Chem Lett; 2010 Feb 01; 20(3):862-5. PubMed ID: 20053558
    [Abstract] [Full Text] [Related]

  • 59. Crystal structure of calf spleen purine nucleoside phosphorylase in a complex with hypoxanthine at 2.15 A resolution.
    Koellner G, Luić M, Shugar D, Saenger W, Bzowska A.
    J Mol Biol; 1997 Jan 17; 265(2):202-16. PubMed ID: 9020983
    [Abstract] [Full Text] [Related]

  • 60. The most potent organophosphorus inhibitors of leucine aminopeptidase. Structure-based design, chemistry, and activity.
    Grembecka J, Mucha A, Cierpicki T, Kafarski P.
    J Med Chem; 2003 Jun 19; 46(13):2641-55. PubMed ID: 12801228
    [Abstract] [Full Text] [Related]

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