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PUBMED FOR HANDHELDS

Journal Abstract Search


94 related items for PubMed ID: 16246052

  • 1. Protein lipidation of BACE.
    Parsons RB, Austen BM.
    Biochem Soc Trans; 2005 Nov; 33(Pt 5):1091-3. PubMed ID: 16246052
    [Abstract] [Full Text] [Related]

  • 2. Protein-protein interactions in the assembly and subcellular trafficking of the BACE (beta-site amyloid precursor protein-cleaving enzyme) complex of Alzheimer's disease.
    Parsons RB, Austen BM.
    Biochem Soc Trans; 2007 Nov; 35(Pt 5):974-9. PubMed ID: 17956258
    [Abstract] [Full Text] [Related]

  • 3. Expression and activity of beta-site amyloid precursor protein cleaving enzyme in Alzheimer's disease.
    Johnston JA, Liu WW, Todd SA, Coulson DT, Murphy S, Irvine GB, Passmore AP.
    Biochem Soc Trans; 2005 Nov; 33(Pt 5):1096-100. PubMed ID: 16246054
    [Abstract] [Full Text] [Related]

  • 4. Regulation of the lipidation of beta-secretase by statins.
    Parsons RB, Farrant JK, Price GC, Subramaniam D, Austen BM.
    Biochem Soc Trans; 2007 Jun; 35(Pt 3):577-82. PubMed ID: 17511656
    [Abstract] [Full Text] [Related]

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  • 7. Novel heparan sulphate analogues: inhibition of beta-secretase cleavage of amyloid precursor protein.
    Patey SJ, Yates EA, Turnbull JE.
    Biochem Soc Trans; 2005 Nov; 33(Pt 5):1116-8. PubMed ID: 16246059
    [Abstract] [Full Text] [Related]

  • 8. The novel beta-secretase inhibitor KMI-429 reduces amyloid beta peptide production in amyloid precursor protein transgenic and wild-type mice.
    Asai M, Hattori C, Iwata N, Saido TC, Sasagawa N, Szabó B, Hashimoto Y, Maruyama K, Tanuma S, Kiso Y, Ishiura S.
    J Neurochem; 2006 Jan; 96(2):533-40. PubMed ID: 16336629
    [Abstract] [Full Text] [Related]

  • 9. Caspase-3 cleavage of GGA3 stabilizes BACE: implications for Alzheimer's disease.
    Vassar R.
    Neuron; 2007 Jun 07; 54(5):671-3. PubMed ID: 17553417
    [Abstract] [Full Text] [Related]

  • 10. Macrocyclic peptidomimetic inhibitors of beta-secretase (BACE): first X-ray structure of a macrocyclic peptidomimetic-BACE complex.
    Rojo I, Martín JA, Broughton H, Timm D, Erickson J, Yang HC, McCarthy JR.
    Bioorg Med Chem Lett; 2006 Jan 01; 16(1):191-5. PubMed ID: 16249081
    [Abstract] [Full Text] [Related]

  • 11. [Secretases as targets for the treatment of Alzheimer's disease].
    Luo HM, Gu F.
    Sheng Li Ke Xue Jin Zhan; 2003 Apr 01; 34(2):189-92. PubMed ID: 12889164
    [No Abstract] [Full Text] [Related]

  • 12. The metabolism of beta-amyloid converting enzyme and beta-amyloid precursor protein processing.
    Benjannet S, Cromlish JA, Diallo K, Chrétien M, Seidah NG.
    Biochem Biophys Res Commun; 2004 Dec 03; 325(1):235-42. PubMed ID: 15522224
    [Abstract] [Full Text] [Related]

  • 13. The carboxyl-terminus of BACE contains a sorting signal that regulates BACE trafficking but not the formation of total A(beta).
    Pastorino L, Ikin AF, Nairn AC, Pursnani A, Buxbaum JD.
    Mol Cell Neurosci; 2002 Feb 03; 19(2):175-85. PubMed ID: 11860271
    [Abstract] [Full Text] [Related]

  • 14. Design and development of BACE-1 inhibitors.
    Cumming JN, Iserloh U, Kennedy ME.
    Curr Opin Drug Discov Devel; 2004 Jul 03; 7(4):536-56. PubMed ID: 15338962
    [Abstract] [Full Text] [Related]

  • 15. Specific enzyme identified that snips APP into beta-amyloid.
    Senior K.
    Drug Discov Today; 2005 Nov 01; 10(21):1408. PubMed ID: 16243255
    [No Abstract] [Full Text] [Related]

  • 16. The proteins BACE1 and BACE2 and beta-secretase activity in normal and Alzheimer's disease brain.
    Stockley JH, O'Neill C.
    Biochem Soc Trans; 2007 Jun 01; 35(Pt 3):574-6. PubMed ID: 17511655
    [Abstract] [Full Text] [Related]

  • 17. Inhibition of amyloid beta-peptide production by blockage of beta-secretase cleavage site of amyloid precursor protein.
    Na CH, Jeon SH, Zhang G, Olson GL, Chae CB.
    J Neurochem; 2007 Jun 01; 101(6):1583-95. PubMed ID: 17542811
    [Abstract] [Full Text] [Related]

  • 18. APPepsilon, the epsilon-secretase-derived N-terminal product of the beta-amyloid precursor protein, behaves as a type I protein and undergoes alpha-, beta-, and gamma-secretase cleavages.
    Lefranc-Jullien S, Sunyach C, Checler F.
    J Neurochem; 2006 May 01; 97(3):807-17. PubMed ID: 16524370
    [Abstract] [Full Text] [Related]

  • 19. BACE1 interacts with lipid raft proteins.
    Hattori C, Asai M, Onishi H, Sasagawa N, Hashimoto Y, Saido TC, Maruyama K, Mizutani S, Ishiura S.
    J Neurosci Res; 2006 Sep 01; 84(4):912-7. PubMed ID: 16823808
    [Abstract] [Full Text] [Related]

  • 20. Amyloid precursor protein and Notch intracellular domains are generated after transport of their precursors to the cell surface.
    Kaether C, Schmitt S, Willem M, Haass C.
    Traffic; 2006 Apr 01; 7(4):408-15. PubMed ID: 16536739
    [Abstract] [Full Text] [Related]


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